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Shanghai Changzheng Hospital

8 clinical trials · 8 recruiting · OTHER

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

Trials by Shanghai Changzheng Hospital

RECRUITINGEarly Phase 1NCT07050394

A Dose-Expansion Trial of Intravenous HNF4α srRNA for Unresectable or Metastatic Colorectal Cancer

This study is a single-arm, open-label, exploratory clinical trial. Building on the previous dose-escalation trial, this dose-expansion trial aims to evaluate the safety and...

Sponsor: Shanghai Changzheng HospitalEnrolling: 201 location
Colorectal Cancer MetastaticColorectal Cancer RecurrentColorectal Cancer Stage IV
RECRUITINGNCT06373081

Anti-CD19-CD3E-CAR-T Cells in Relapsed/Refractory Autoimmune Disease

This is an investigator-initiated trial to evaluate the safety and efficacy of anti-CD19-CD3E-CAR-T cells in the relapse or refractory autoimmune diseases.

Sponsor: Shanghai Changzheng HospitalEnrolling: 61 location
Systemic Lupus Erythematosus (SLE)Sjogren's SyndromeSystemic Sclerosis+3
RECRUITINGEarly Phase 1NCT07185932

Efficacy and Safety of Rifaximin in Treating MAFLD

Study Objective: to evaluate the efficacy and safety of rifaximin in the treatment of metabolic-associated fatty liver disease (MAFLD), and investigate the underlying mechanisms...

Sponsor: Shanghai Changzheng HospitalEnrolling: 401 location
Metabolic-associated Fatty Liver Disease
RECRUITINGNCT07381413

Eye Tracking Study on Eye Movement Function and Visual Attention Patterns in Patients With Thyroid-Associated...

This study focuses on eye health and visual function in patients with Thyroid-Associated Ophthalmopathy (TAO), a condition that often causes bulging eyes and restricted eye...

Sponsor: Shanghai Changzheng HospitalEnrolling: 1001 location
Thyroid Associated OphthalmopathiesEye Tracking
RECRUITINGPhase 4NCT07152340

The Safety and Efficacy of Sequential Hormone Therapy and IBI311 Therapy in Patients With Active Moderate to Severe TAO...

Thyroid-associated ophthalmopathy (TAO) is an organ-specific autoimmune disease closely related to thyroid disease, which leads the incidence of orbital disease in adults and is...

Sponsor: Shanghai Changzheng HospitalEnrolling: 642 locations
Thyroid Associated Ophthalmopathies
RECRUITINGPhase 4NCT07152366

Efficacy and Safety of Sequential Hormone Therapy and Tetuzumab Therapy in Patients With Moderate to Severe TAO in the...

Thyroid-associated ophthalmopathy (TAO) is an organ-specific autoimmune disease closely related to thyroid disease, which leads the incidence of orbital disease in adults and is...

Sponsor: Shanghai Changzheng HospitalEnrolling: 961 location
Thyroid Associated Ophthalmopathies
RECRUITINGPhase 2NCT06078969

Oral Prednisone in Treating LCH of Bone in Childhood and Adolescence

Langerhans cell histiocytosis (LCH) of bone is a benign-tumor-like osteolytic lesion in childhood and adolescence, which is characterized by the aberrant activation of antigen...

Sponsor: Shanghai Changzheng HospitalEnrolling: 1181 location
Langerhans Cell Histiocytosis of Bone
RECRUITINGNCT07363824

A Study on the Correlation Between Tear Iron Levels and the Severity of Dry Eye Disease.

This study aims to see if the amount of iron in tears is linked to how severe dry eye disease is. We hope this can lead to a new way to help diagnose and understand dry eye. This...

Sponsor: Shanghai Changzheng HospitalEnrolling: 521 location
Dry Eye DiseaseIron