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Severe Hemophilia A Clinical Trials

Reviewed by TrialFinderData Editorial Team · Updated

5 recruiting trials for Severe Hemophilia A. Eligibility criteria explained in plain English.

TrialFinderData lists 5 Severe Hemophilia A clinical trials drawn from ClinicalTrials.gov, all of which are currently recruiting participants.

Across the trials that carry a phase, Phase 3 is the largest group at 50% (2 studies); the largest phase groups are Phase 3: 2, Phase 1: 1, Phase 4: 1.

Research is led by Hangzhou Gensciences Biopharmaceutical Co., Ltd. (2), Pfizer (1), Octapharma (1), among the most active sponsors registered for these trials.

The most frequently studied intervention is MARSTACIMAB (drug, 1 trial), followed by FRSW117, Nuwiq.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
5
Total Trials
5
Recruiting Now
2
Phase 3 Trials
4
Sponsors

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Recruiting Trials

Clinical trial data sourced from the ClinicalTrials.gov registry, maintained by the National Library of Medicine. Always consult your doctor before considering any clinical trial.

RECRUITINGPhase 1NCT06703606

A Study to Learn About How Changing Therapy From Emicizumab to Marstacimab Affects People With the Severe Hemophilia A.

The purpose of the study is to learn about safety, how the body processes marstacimab and how it works in patients with severe hemophilia A without inhibitors. Hemophilia A is...

Sponsor: PfizerEnrolling: 157 locations
RECRUITINGPhase 3NCT06142552

Phase 3 Clinical Project of Pegylated Recombinant Human Coagulation Factor VIII-Fc Fusion Protein

To evaluate the prophylactic efficacy of recombinant human coagulation factor Ⅷ-Fc fusion protein (FRSW117) for injection in patients with severe hemophilia A. To evaluate the...

Sponsor: Hangzhou Gensciences Biopharmaceutical Co., Ltd.Enrolling: 12020 locations
RECRUITINGPhase 4NCT05935358

Nuwiq for Perioperative Management Of Patients With Haemophilia A on Emicizumab Regular Prophylaxis Study

Recombinant factor VIII for the prevention of bleeding in patients with severe haemophilia A undergoing major surgery while receiving emicizumab prophylaxis

Sponsor: OctapharmaEnrolling: 2818 locations
RECRUITINGPhase 3NCT07663903

Study of Recombinant Human Coagulation Factor VIII-Fc Fusion Protein (FRSW107) On-Demand Treatment

The indication for this product is to control bleeding in patients with hemophilia A (congenital deficiency of factor VIII). The primary objective: Evaluation of the efficacy of...

Sponsor: Hangzhou Gensciences Biopharmaceutical Co., Ltd.Enrolling: 6020 locations
RECRUITINGNCT05802836

Dynamics of the Anti-factor VIII Antibody Signature During Treatment With Emicizumab

The goal of this observational study is to learn about the changes of antibodies and inhibitors against the coagulation factor VIII in patients with severe hemophilia A receiving...

Sponsor: Christoph KönigsEnrolling: 1001 location

Frequently Asked Questions

There are currently 5 clinical trials for Severe Hemophilia A, with 5 actively recruiting participants. These include trials across all phases from early-stage Phase 1 to late-stage Phase 3.

To join a clinical trial for Severe Hemophilia A, review the eligibility criteria on the trial detail pages, then talk to your doctor about whether a trial is right for you. Your doctor can help you evaluate the potential benefits and risks.

Phase 3 trials are large-scale studies that test whether a treatment is effective and monitor side effects. There are 2 Phase 3 trials for Severe Hemophilia A, representing treatments closest to potential FDA approval.

Clinical trials follow strict safety protocols overseen by Institutional Review Boards (IRBs) and the FDA. Participants are monitored closely and can withdraw at any time. Always discuss risks and benefits with your healthcare provider before enrolling.

Sources: ClinicalTrials.gov, FDA
Last updated:

Trial data sourced from the ClinicalTrials.gov API. This site does not provide medical advice, always talk to your doctor about clinical trial participation.