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Sickle Cell Anemia Clinical Trials

Reviewed by TrialFinderData Editorial Team · Updated

7 recruiting trials for Sickle Cell Anemia. Eligibility criteria explained in plain English.

TrialFinderData lists 7 Sickle Cell Anemia clinical trials drawn from ClinicalTrials.gov, all of which are currently recruiting participants.

Across the trials that carry a phase, Phase 1 / Phase 2 is the largest group at 33% (1 studies); the largest phase groups are Phase 1 / Phase 2: 1, Phase 2: 1, Phase 3: 1.

Research is led by Children's Hospital Medical Center, Cincinnati (3), Adly A Adam (1), Paul Szabolcs (1), among the most active sponsors registered for these trials.

The most frequently studied intervention is Pressure pain tolerance measurement using Digital Pressure Algometer (other, 1 trial), followed by Balance assessment using HUMAC balance system, Lower limb muscular strength using Lafayette hand held dynamometer.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
7
Total Trials
7
Recruiting Now
1
Phase 3 Trials
5
Sponsors

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Recruiting Trials

Clinical trial data sourced from the ClinicalTrials.gov registry, maintained by the National Library of Medicine. Always consult your doctor before considering any clinical trial.

RECRUITINGNCT07116772

Serial Assessment of Fertility Experiences

The SAFE study is a long-term research project that watches people with sickle cell anemia (SCA) over time. The main goal is to see how a medicine called hydroxyurea affects their...

Sponsor: Children's Hospital Medical Center, CincinnatiEnrolling: 2503 locations
RECRUITINGNCT07356050

Verifying Antibodies After Live Immunization Delivery (VALID): A Study of Measles Vaccine Immunogenicity in Children...

The goal of this study is to learn if infants with sickle cell disease (SCD) develop adequate protection after measles vaccines. (not looking at any prolonged duration)

Sponsor: Children's Hospital Medical Center, CincinnatiEnrolling: 1303 locations
RECRUITINGNCT06529874

Pressure Pain Tolerance in Relation to Balance and Strength in Children

Sickle cell disease (SCD) is the most frequent life-threatening genetic hemoglobinopathy in the world and occurs due to the synthesis of abnormal hemoglobin S (HbS).Cells with...

Sponsor: Adly A AdamEnrolling: 801 location
RECRUITINGPhase 1 / Phase 2NCT03653338

T-Cell Depleted Alternative Donor Bone Marrow Transplant for Sickle Cell Disease (SCD) and Other Anemias

The purpose of this study is to evaluate what effect, if any, mismatched unrelated volunteer donor and/or haploidentical related donor stem cell transplant may have on severe...

Sponsor: Paul SzabolcsEnrolling: 51 location
RECRUITINGPhase 2NCT06016634

Alendronate for Osteonecrosis in Adults With Sickle Cell Disease

A prospective, single-arm, intervention study of oral alendronate in adults with sickle cell disease and osteonecrosis

Sponsor: University of California, DavisEnrolling: 301 location
RECRUITINGPhase 3NCT05477563

Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia...

This is a single-dose, open-label study in participants with transfusion-dependent β-thalassemia (TDT) or severe sickle cell disease (SCD). The study will evaluate the safety and...

Sponsor: Vertex Pharmaceuticals IncorporatedEnrolling: 266 locations
RECRUITINGNCT04093986

Hydroxyurea Exposure Limiting Pregnancy and Follow-Up Lactation

The purpose of this research study is to document and understand the effects of hydroxyurea exposure for women with SCD and their babies, during both gestation and lactation.

Sponsor: Children's Hospital Medical Center, CincinnatiEnrolling: 2001 location

Frequently Asked Questions

There are currently 7 clinical trials for Sickle Cell Anemia, with 7 actively recruiting participants. These include trials across all phases from early-stage Phase 1 to late-stage Phase 3.

To join a clinical trial for Sickle Cell Anemia, review the eligibility criteria on the trial detail pages, then talk to your doctor about whether a trial is right for you. Your doctor can help you evaluate the potential benefits and risks.

Phase 3 trials are large-scale studies that test whether a treatment is effective and monitor side effects. There are 1 Phase 3 trials for Sickle Cell Anemia, representing treatments closest to potential FDA approval.

Clinical trials follow strict safety protocols overseen by Institutional Review Boards (IRBs) and the FDA. Participants are monitored closely and can withdraw at any time. Always discuss risks and benefits with your healthcare provider before enrolling.

Sources: ClinicalTrials.gov, FDA
Last updated:

Trial data sourced from the ClinicalTrials.gov API. This site does not provide medical advice, always talk to your doctor about clinical trial participation.