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Solid Tumor, Adult Clinical Trials

Reviewed by TrialFinderData Editorial Team · Updated

13 recruiting trials for Solid Tumor, Adult. Eligibility criteria explained in plain English.

TrialFinderData lists 13 Solid Tumor, Adult clinical trials drawn from ClinicalTrials.gov, all of which are currently recruiting participants.

Across the trials that carry a phase, Phase 1 / Phase 2 is the largest group at 50% (6 studies); the largest phase groups are Phase 1 / Phase 2: 6, Phase 1: 4, Phase 2: 2.

Research is led by A2 Biotherapeutics Inc. (2), Krystal Biotech, Inc. (1), TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics) (1), among the most active sponsors registered for these trials.

The most frequently studied intervention is Pembrolizumab (KEYTRUDA®) (drug, 2 trials), followed by Apheresis, Next Generation Sequencing (NGS).

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
13
Total Trials
13
Recruiting Now
0
Phase 3 Trials
10
Sponsors

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Recruiting Trials

Clinical trial data sourced from the ClinicalTrials.gov registry, maintained by the National Library of Medicine. Always consult your doctor before considering any clinical trial.

RECRUITINGNCT04981119

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

Objective: To collect information on how often a solid tumor cancer might lose the Human Leukocyte Antigen (HLA) by next generation sequencing and perform apheresis to collect...

Sponsor: A2 Biotherapeutics Inc.Enrolling: 20016 locations
RECRUITINGPhase 1 / Phase 2NCT06228326

A Study Assessing KB707 for the Treatment of Advanced Solid Tumor Malignancies Affecting the Lungs

The Sponsor is developing KB707, a replication-defective, non-integrating herpes simplex virus type 1 (HSV-1)-derived vector designed to stimulate an anti-tumor immune response...

Sponsor: Krystal Biotech, Inc.Enrolling: 25014 locations
RECRUITINGPhase 1NCT06625775

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

First in human study to evaluate the safety, tolerability, and pharmacokinetics (PK) of BBO-10203, a PI3Kα:RAS breaker, alone and in combination with other anti-cancer agents in...

Sponsor: TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)Enrolling: 39220 locations
RECRUITINGPhase 2NCT04165772

Study of Induction PD-1 Blockade in Subjects With Locally Advanced Mismatch Repair Deficient Solid Tumors

The purpose of this study is to find out whether the study drug, TSR-042, followed by standard chemoradiotherapy (the chemotherapy drug capecitabine + radiation therapy) and...

Sponsor: Memorial Sloan Kettering Cancer CenterEnrolling: 21210 locations
RECRUITINGPhase 1 / Phase 2NCT03919292

Neratinib + Valproate in Advanced Solid Tumors, w/Expansion Cohort in Ras-Mutated Ca

To determine the recommended phase 2 dose (RP2D) of the combination of neratinib and sodium valproate when given to patients with advanced solid tumors. Then to explore the...

Sponsor: Virginia Commonwealth UniversityEnrolling: 831 location
RECRUITINGPhase 1NCT06196294

GPC3/Mesothelin-CAR-γδT Cells Against Cancers

The third generation of GPC3/mesothelin targeted CAR-γδT cells have been constructed and their anti-cancer function has been verified by multiple in vitro and in vivo studies....

Sponsor: Second Affiliated Hospital of Guangzhou Medical UniversityEnrolling: 301 location
RECRUITINGPhase 1 / Phase 2NCT03686124

ACTengine® IMA203/IMA203CD8 as Monotherapy or in Combination With Nivolumab in Recurrent and/or Refractory Solid Tumors

The study's purpose is to establish the safety and tolerability of IMA203/IMA203CD8 products with or without combination with nivolumab in patients with solid tumors that express...

Sponsor: Immatics US, Inc.Enrolling: 37520 locations
RECRUITINGPhase 1NCT06398418

R-5780-01 In Combination With PD-1 Checkpoint Inhibitors (Checkpoint Protein on Immune Cells Called T Cells) in...

The goal of this study is determine the safety and tolerability of orally taken probiotic (R-5780) in patients currently on a PD-1 Pathway Checkpoint Inhibitor (checkpoint protein...

Sponsor: Rise Therapeutics LLCEnrolling: 331 location
RECRUITINGPhase 1NCT06444815

A Study of VET3-TGI in Patients With Solid Tumors

VET3-TGI is an oncolytic immunotherapy designed to treat advanced cancers. VET3-TGI has not been given to human patients yet, and the current study is designed to find a safe and...

Sponsor: KaliVir ImmunotherapeuticsEnrolling: 607 locations
RECRUITINGPhase 2NCT04673942

A Study of AdAPT-001 in Subjects With Sarcoma and Refractory Solid Tumors

AdAPT-001 is an oncolytic virus that is injected directly into the tumor or via intraarterial administration. The purpose of this study is to find out if AdAPT-001 is safe and...

Sponsor: EpicentRx, Inc.Enrolling: 1406 locations
RECRUITINGPhase 1 / Phase 2NCT04665206

Study to Evaluate VT3989 in Patients With Metastatic Solid Tumors

This is an open-label, dose escalation and expansion study to evaluate the safety, tolerability, PK, and biological activity of VT3989 administered, alone or in combination, once...

Sponsor: Vivace Therapeutics, IncEnrolling: 43412 locations
RECRUITINGPhase 1 / Phase 2NCT05086692

A Beta-only IL-2 ImmunoTherapY Study

This is a Phase 1/2, multi-center, open-label, dose-escalation and expansion study to evaluate safety and tolerability, PK, pharmacodynamic, and early signal of anti-tumor...

Sponsor: Medicenna Therapeutics, Inc.Enrolling: 11520 locations
RECRUITINGPhase 1 / Phase 2NCT06051695

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid...

The goal of this study is to test autologous logic-gated Tmod™ CAR T-cell products in subjects with solid tumors including colorectal cancer (CRC), pancreatic cancer (PANC),...

Sponsor: A2 Biotherapeutics Inc.Enrolling: 47412 locations

Frequently Asked Questions

There are currently 13 clinical trials for Solid Tumor, Adult, with 13 actively recruiting participants. These include trials across all phases from early-stage Phase 1 to late-stage Phase 3.

To join a clinical trial for Solid Tumor, Adult, review the eligibility criteria on the trial detail pages, then talk to your doctor about whether a trial is right for you. Your doctor can help you evaluate the potential benefits and risks.

Phase 3 trials are large-scale studies that test whether a treatment is effective and monitor side effects. There are 0 Phase 3 trials for Solid Tumor, Adult, representing treatments closest to potential FDA approval.

Clinical trials follow strict safety protocols overseen by Institutional Review Boards (IRBs) and the FDA. Participants are monitored closely and can withdraw at any time. Always discuss risks and benefits with your healthcare provider before enrolling.

Sources: ClinicalTrials.gov, FDA
Last updated:

Trial data sourced from the ClinicalTrials.gov API. This site does not provide medical advice, always talk to your doctor about clinical trial participation.