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Treatment Resistant Depression Clinical Trials

Reviewed by TrialFinderData Editorial Team · Updated

7 recruiting trials for Treatment Resistant Depression. Eligibility criteria explained in plain English.

TrialFinderData lists 7 Treatment Resistant Depression clinical trials drawn from ClinicalTrials.gov, all of which are currently recruiting participants.

Across the trials that carry a phase, Phase 2 is the largest group at 50% (1 studies); the largest phase groups are Phase 2: 1, Phase 1: 1.

Research is led by Centre for Addiction and Mental Health (2), Stanford University (1), Mark Niciu (1), among the most active sponsors registered for these trials.

The most frequently studied intervention is Psilocybin 25 mg (drug, 1 trial), followed by Risperidone 1 MG, Active Comparator: Active aiTBS.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
7
Total Trials
7
Recruiting Now
0
Phase 3 Trials
6
Sponsors

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Recruiting Trials

Clinical trial data sourced from the ClinicalTrials.gov registry, maintained by the National Library of Medicine. Always consult your doctor before considering any clinical trial.

RECRUITINGPhase 2NCT06512220

Imaging the Effects of Serotonin 2A Receptor Modulation on Synaptic Density in Treatment-resistant Depression (SYNVEST)

Limit: 5000 characters. Psilocybin, the chemical component of "magic mushrooms", has been administered with psychotherapy in several randomized clinical trials (RCTs) showing...

Sponsor: Centre for Addiction and Mental HealthEnrolling: 121 location
RECRUITINGNCT05849402

Accelerated Intermittent Theta-Burst Stimulation (aiTBS) in Treatment-Resistant Depression of Bipolar II Disorder

The purpose of this study is to investigate the effectiveness of accelerated intermittent theta-burst transcranial magnetic stimulation (aiTBS) in inducing anti-depressant...

Sponsor: Stanford UniversityEnrolling: 601 location
RECRUITINGNCT04480918

University of Iowa Interventional Psychiatry Service Patient Registry

The purpose of this study is to examine the effects of interventional/procedural therapies for treatment-resistant depression (TRD) and Obsessive-Compulsive Disorder (OCD). These...

Sponsor: Mark NiciuEnrolling: 10001 location
RECRUITINGPhase 1NCT06731621

Psilocybin for Treatment-Resistant Depression in Autism

We propose a first-of-its-kind open-label clinical trial to investigate the feasibility, tolerability, and safety of administering psilocybin in autistic adults with...

Sponsor: Centre for Addiction and Mental HealthEnrolling: 201 location
RECRUITINGNCT06423430

Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)

The goal of this clinical trial is to evaluate the effectiveness and safety of bilateral stimulation of the subcallosal cingulate white matter (SCCwm) using Deep Brain Stimulation...

Sponsor: Abbott Medical DevicesEnrolling: 10020 locations
RECRUITINGNCT07108257

Magnetic Resonance-Guided Focused Ultrasound Bilateral Capsulotomy for the Treatment of Refractory Bipolar Depression

The goal of this clinical trial is to evaluate the safety and initial effectiveness of MR-guided focused ultrasound (MRgFUS) bilateral capsulotomy in patients with...

Sponsor: Sunnybrook Health Sciences CentreEnrolling: 101 location
RECRUITINGNCT06462196

Natural History of Depression, Bipolar Disorder and Suicide Risk

Mood disorders, such as depression and bipolar disorder, are difficult to treat. One reason is that there are no objective ways to measure how these disorders affect the body and...

Sponsor: National Institute of Mental Health (NIMH)Enrolling: 5001 location

Frequently Asked Questions

There are currently 7 clinical trials for Treatment Resistant Depression, with 7 actively recruiting participants. These include trials across all phases from early-stage Phase 1 to late-stage Phase 3.

To join a clinical trial for Treatment Resistant Depression, review the eligibility criteria on the trial detail pages, then talk to your doctor about whether a trial is right for you. Your doctor can help you evaluate the potential benefits and risks.

Phase 3 trials are large-scale studies that test whether a treatment is effective and monitor side effects. There are 0 Phase 3 trials for Treatment Resistant Depression, representing treatments closest to potential FDA approval.

Clinical trials follow strict safety protocols overseen by Institutional Review Boards (IRBs) and the FDA. Participants are monitored closely and can withdraw at any time. Always discuss risks and benefits with your healthcare provider before enrolling.

Sources: ClinicalTrials.gov, FDA
Last updated:

Trial data sourced from the ClinicalTrials.gov API. This site does not provide medical advice, always talk to your doctor about clinical trial participation.