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TrialFinderData is for informational purposes only and does not provide medical advice. Always talk to your doctor.

Updated June 2026 · ClinicalTrials.gov

Centre for Addiction and Mental Health

Reviewed by TrialFinderData Editorial Team · Updated

7 clinical trials · 7 recruiting · OTHER

Centre for Addiction and Mental Health has 7 clinical trials registered on ClinicalTrials.gov, with 7 actively recruiting participants. The trials listed below cover 9 conditions across the phases listed in the sidebar. Always discuss any specific trial with your physician before contacting a study site.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About Centre for Addiction and Mental Health\'s Trial Portfolio

Centre for Addiction and Mental Health is a non-industry sponsor (academic medical center, hospital, foundation, or research network). Non-industry sponsors often investigate novel approaches, rare conditions, and behavioral or surgical interventions that commercial sponsors may not prioritize.

7 of Centre for Addiction and Mental Health's 7 registered trials are currently recruiting — roughly 100% of the portfolio. A high recruiting share usually points to an active research pipeline with multiple programs at the enrollment stage.

Centre for Addiction and Mental Health's research footprint spans Treatment Resistant Depression (2 trials), Schizophrenia (2), and Autism Spectrum Disorder (1) as the top three conditions. The full condition list, sorted by trial count, is in the sidebar.

Not Applicable is the largest single phase in Centre for Addiction and Mental Health's portfolio at 57% of registered trials. The full phase breakdown appears in the sidebar.

Trials by Centre for Addiction and Mental Health

RECRUITINGPhase 2NCT06512220

Imaging the Effects of Serotonin 2A Receptor Modulation on Synaptic Density in Treatment-resistant Depression (SYNVEST)

Limit: 5000 characters. Psilocybin, the chemical component of "magic mushrooms", has been administered with psychotherapy in several randomized clinical trials (RCTs) showing...

Sponsor: Centre for Addiction and Mental HealthEnrolling: 121 location
Treatment Resistant Depression
RECRUITINGPhase 1NCT06731621

Psilocybin for Treatment-Resistant Depression in Autism

We propose a first-of-its-kind open-label clinical trial to investigate the feasibility, tolerability, and safety of administering psilocybin in autistic adults with...

Sponsor: Centre for Addiction and Mental HealthEnrolling: 201 location
Treatment Resistant DepressionAutism Spectrum Disorder
RECRUITINGNCT05153369

Three-level Model of DBT-informed Care for Youth With and/or at Familial Risk for Bipolar Disorder (DB3)

This study seeks to bridge the knowledge-to-action gap regarding psychosocial treatment "dosing" for youth with and/or at familial risk for bipolar disorder (BD). In psychiatry,...

Sponsor: Centre for Addiction and Mental HealthEnrolling: 601 location
Bipolar Disorder
RECRUITINGPhase 4NCT02639702

Switching From Twice-Daily to Once-Daily Clozapine Dosing in Schizophrenia

Plasma half-life has routinely been used to establish the dosing schedule of antipsychotics; for example, it is recommended that agents with a short plasma half-life be...

Sponsor: Centre for Addiction and Mental HealthEnrolling: 301 location
SchizophreniaSchizoaffective Disorder
RECRUITINGNCT05748990

Does Abnormal Insulin Action in the Brain Underlie Cognitive and Metabolic Dysfunction in Schizophrenia

Cognitive impairment (such as challenges in thinking and memory) is a core aspect of schizophrenia (SCZ), contributing to disability and poor functional outcomes. Additionally,...

Sponsor: Centre for Addiction and Mental HealthEnrolling: 201 location
SchizophreniaHealthy
RECRUITINGNCT04033679

The Effects of Non-invasive Brain Stimulation on Treatment Adherence in Schizophrenia

This study seeks to explore the effects of transcranial direct current stimulation (tDCS), a non-invasive method of brain stimulation, as an adjunctive treatment to improve...

Sponsor: Centre for Addiction and Mental HealthEnrolling: 1061 location
Schizophrenia;Schizoaffective
RECRUITINGNCT06942559

Brain-Oscillation Synchronized Stimulation of the DMPFC

This trial aims to obtain initial evidence about the clinical efficacy and modulation of neurophysiological markers in obsessive compulsive disorder (OCD) using personalized...

Sponsor: Centre for Addiction and Mental HealthEnrolling: 481 location
Obsessive Compulsive Disorder (OCD)Treatment Resistant Obsessive Compulsive Disorder

How to Approach a Trial Listing

Each trial card above links to a dedicated page with the official ClinicalTrials.gov data plus a plain-English translation of the eligibility criteria. We translate technical terminology (ECOG performance status, hepatic function values, exclusionary lab thresholds) into language that a patient or caregiver can understand, but the original clinical text and the live ClinicalTrials.gov record always govern any actual eligibility decision.

Before contacting a trial site, write down questions for your treating physician using the framework on our 25 Questions guide. Discuss whether the trial fits your treatment plan, what the time commitment looks like, and whether your insurance will cover the standard-of-care portions. Trials are not a substitute for a treatment plan — they are an addition that needs medical guidance to evaluate.

Authoritative Resources

Verify any trial registration directly on ClinicalTrials.gov. For background on the FDA approval pathway that Phase 3 trials feed into, see the FDA drug approval process. For cancer-specific trial guidance, the National Cancer Institute publishes patient-oriented overviews. For global trial registrations beyond the U.S., the WHO ICTRP aggregates registries from around the world.

Frequently Asked Questions

How many clinical trials does Centre for Addiction and Mental Health have on ClinicalTrials.gov?

Centre for Addiction and Mental Health has 7 clinical trials registered on the federal ClinicalTrials.gov registry, of which 7 are actively recruiting participants right now. These counts come directly from the ClinicalTrials.gov API and are updated as the registry changes.

What conditions does Centre for Addiction and Mental Health study?

Centre for Addiction and Mental Health's registered trials cover 9 conditions on ClinicalTrials.gov, led by Treatment Resistant Depression (2 trials), Schizophrenia (2 trials), Autism Spectrum Disorder (1 trial), Bipolar Disorder (1 trial), Schizoaffective Disorder (1 trial). The complete condition list appears in the sidebar of this page; each condition links to a page listing every recruiting trial in that area, regardless of sponsor.

How do I join a Centre for Addiction and Mental Health clinical trial?

Joining a clinical trial is a medical decision that should always involve your treating physician. Each trial page on this site includes the eligibility criteria translated into plain English alongside the official clinical text, plus the contact information that the sponsor has registered with ClinicalTrials.gov. Bring the trial information to your doctor before reaching out — they can review the full inclusion and exclusion criteria against your medical history and help you decide whether to pursue screening.

What does the trial phase mean?

Phase 1 trials test safety and dosing in small groups (often 20–80 healthy volunteers or patients). Phase 2 trials evaluate efficacy and side effects in larger groups (100–300 patients with the target condition). Phase 3 trials confirm efficacy and monitor safety in the largest groups (300–3,000+ patients) and form the basis of an FDA approval submission. Phase 4 studies happen after a treatment is approved, monitoring long-term safety and effectiveness in real-world use. Some trials register without a phase — common for device, behavioral, or observational studies.

Where does this trial data come from?

All trial data is pulled directly from the ClinicalTrials.gov API v2, the official federal trial registry maintained by the National Library of Medicine at NIH. Under FDAAA 801, most U.S. drug and device trials are required to register, making ClinicalTrials.gov the most comprehensive source. Sponsors are responsible for keeping their listings current; trial status can shift between data refreshes.

How This Sponsor Page Is Built

Every count on this page is derived directly from ClinicalTrials.gov API v2 records. Trial counts include all trials currently registered to this sponsor; the recruiting count reflects trials with status "Recruiting" or equivalent. Plain-English eligibility translations on each linked trial page preserve the original clinical text alongside an accessible version. Read the full methodology for the data pipeline and limitations.

Source: ClinicalTrials.gov API v2, maintained by the National Library of Medicine at NIH. Public domain. Cite as: "TrialFinderData. Data: ClinicalTrials.gov."

Medical disclaimer: This page is informational, not medical advice. Talk to your doctor about whether a clinical trial is right for you.

Last updated 2026-06-26 · 7 trials tracked for Centre for Addiction and Mental Health.