Clinical Trials in Pennsylvania

Pennsylvania has 606 clinical trials currently recruiting participants, ranking #6 among all states. The most-studied condition is Cystic Fibrosis with 11 active trials.

606

Total Trials

606

Recruiting

National Rank

Conditions

Trials by Phase

265

Not Applicable

Phase 1 / Phase 2

Phase 2 / Phase 3

Early Phase 1

Phase 1

109

Phase 2

Phase 3

Phase 4

Top Conditions in Pennsylvania

#	Condition	Trials
1	Cystic Fibrosis	11
2	Sickle Cell Disease	9
3	Duchenne Muscular Dystrophy	8
4	Alzheimer Disease	8
5	Stroke	8
6	Esophageal Cancer	7
7	Colorectal Cancer	7
8	Psoriatic Arthritis	7
9	Melanoma	7
10	Ovarian Cancer	7
11	Bipolar Disorder	7
12	Autism Spectrum Disorder	7
13	NSCLC	6
14	Schizophrenia	6
15	Mesothelioma	6
16	Renal Cell Carcinoma	6
17	Advanced Solid Tumor	6
18	Traumatic Brain Injury	6
19	Obesity	6
20	Ulcerative Colitis	6

Top Sponsors in Pennsylvania

#	Sponsor	Trials
1	University of Pennsylvania	54
2	University of Pittsburgh	40
3	Children's Hospital of Philadelphia	16
4	Abramson Cancer Center at Penn Medicine	15
5	Thomas Jefferson University	11
6	Milton S. Hershey Medical Center	9
7	Merck Sharp & Dohme LLC	9
8	Hoffmann-La Roche	9
9	Eli Lilly and Company	8
10	Penn State University	8
11	National Institute of Allergy and Infectious Diseases (NIAID)	7
12	National Cancer Institute (NCI)	7
13	Paul Szabolcs	6
14	Massachusetts General Hospital	6
15	Memorial Sloan Kettering Cancer Center	5

Cities With Most Trials in Pennsylvania

#	City	Trials
1	Philadelphia	357
2	Pittsburgh	223
3	Hershey	26
4	Erie	12
5	Duncansville	10
6	Allentown	6
7	Lancaster	6
8	Bethlehem	6
9	University Park	6
10	Wynnewood	4
11	Harrisburg	4
12	York	3
13	Easton	3
14	Elkins Park	3
15	DuBois	3

Important: This information is for research purposes only. Always talk to your doctor about whether a clinical trial is right for you.

Frequently Asked Questions

Pennsylvania currently has 606 clinical trials actively recruiting participants, making it #6 nationally by total trial count.

The most-studied conditions in Pennsylvania are Cystic Fibrosis (11 trials), Sickle Cell Disease (9 trials), Duchenne Muscular Dystrophy (8 trials).

Browse the conditions listed on this page to find trials recruiting in Pennsylvania. Each condition page shows trial details, eligibility criteria in plain English, and contact information. Always talk to your doctor about whether a trial is right for you.

Sources: ClinicalTrials.gov

Trial counts reflect currently recruiting studies listed on ClinicalTrials.gov with locations in this state.

Pennsylvania Trial Details →All State Statistics →

The this entity category groups every U.S. clinical trials and research registries entity sharing this attribute. The list above is the data; the paragraphs below explain what the grouping means against the broader the NIH ClinicalTrials.gov registry distribution and how to read the relative rankings within the category.

For readers using this category as a starting point, the per-entity detail pages linked from the table above carry the underlying the NIH ClinicalTrials.gov registry data in full. The category-level view is the filter; the per-entity pages are the actual answer.

Source: ClinicalTrials.gov, 2026.