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Updated June 2026 · ClinicalTrials.gov

Bristol-Myers Squibb

Reviewed by TrialFinderData Editorial Team · Updated

27 clinical trials · 27 recruiting · INDUSTRY

Bristol-Myers Squibb has 27 clinical trials registered on ClinicalTrials.gov, with 27 actively recruiting participants. The trials listed below cover 20 conditions across the phases listed in the sidebar. Always discuss any specific trial with your physician before contacting a study site.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About Bristol-Myers Squibb\'s Trial Portfolio

Bristol-Myers Squibb is an industry sponsor — typically a pharmaceutical, biotechnology, or medical device company. Industry sponsors fund and run the largest share of registered trials in the United States and are subject to FDA registration requirements under the FDA Amendments Act (FDAAA 801) for most drug and device studies.

27 of Bristol-Myers Squibb's 27 registered trials are currently recruiting — roughly 100% of the portfolio. A high recruiting share usually points to an active research pipeline with multiple programs at the enrollment stage.

Bristol-Myers Squibb's research footprint spans Schizophrenia (4 trials), Plaque Psoriasis (4), and Alzheimer Disease (2) as the top three conditions. The full condition list, sorted by trial count, is in the sidebar.

Bristol-Myers Squibb's portfolio is weighted toward later-stage research — Phase 3 accounts for 33% of registered trials. Later-stage trials are the ones most likely to lead directly to FDA approval decisions, and they typically enroll the largest patient cohorts.

Trials by Bristol-Myers Squibb

RECRUITINGPhase 1 / Phase 2NCT06618287

A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult...

The purpose of this study is to evaluate the safety, tolerability, drug levels, and preliminary efficacy of BMS-986507 combinations in adult participants with advanced solid...

Sponsor: Bristol-Myers SquibbEnrolling: 41620 locations
Lung CancerBreast Cancer
RECRUITINGPhase 1NCT06764771

A Study of BMS-986488 as Monotherapy and Combination Therapy in Participants With Advanced Malignant Tumors

This purpose of this study is to determine if experimental treatment with BMS-986488, alone, or in combinations is safe, tolerable, and has anti-cancer activity in patients with...

Sponsor: Bristol-Myers SquibbEnrolling: 4378 locations
Advanced Malignant Tumors
RECRUITINGPhase 2NCT06855771

A Study of Navlimetostat (BMS-986504) in Participants With Pre-treated Advanced or Metastatic Non-small Cell Lung...

The purpose of this study is to evaluate the safety and efficacy of Navlimetostat (BMS-986504) monotherapy in participants with advanced or metastatic Non-small Cell Lung Cancer...

Sponsor: Bristol-Myers SquibbEnrolling: 13020 locations
Carcinoma, Non-Small-Cell Lung
RECRUITINGPhase 1 / Phase 2NCT07293351

A Study to Evaluate the Safety, Tolerability, and Efficacy of Pumitamig Alone or in Combination With Ipilimumab or...

The purpose of this study is to evaluate the safety, tolerability, and efficacy of Pumitamig alone or in combination with Ipilimumab or Cabozantinib in participants with advanced...

Sponsor: Bristol-Myers SquibbEnrolling: 25420 locations
Advanced Renal Cell Carcinoma (RCC)
RECRUITINGPhase 1 / Phase 2NCT06730750

A Study of BMS-986490 With or Without Bevacizumab in Advanced Solid Tumors

This is a study of BMS-986490 as a monotherapy and in combination with bevacizumab in participants with select advanced solid tumors known to express CEACAM5.

Sponsor: Bristol-Myers SquibbEnrolling: 3606 locations
Advanced Solid Tumors
RECRUITINGPhase 3NCT05827016

A Study to Compare Iberdomide Maintenance Versus Lenalidomide Maintenance Therapy Following Autologous Stem Cell...

The purpose of this study is to compare the effectiveness of iberdomide maintenance to lenalidomide maintenance therapy after autologous stem cell transplantation (ASCT) in...

Sponsor: Bristol-Myers SquibbEnrolling: 121620 locations
Multiple Myeloma
RECRUITINGPhase 1NCT05245500

Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion

This is a Phase 1, open-label, multicenter, study of the safety, tolerability, PK, PD, and anti-tumor activity of MRTX1719 patients with advanced, unresectable or metastatic solid...

Sponsor: Bristol-Myers SquibbEnrolling: 33620 locations
MesotheliomaNon Small Cell Lung CancerMalignant Peripheral Nerve Sheath Tumors+3
RECRUITINGPhase 3NCT06937229

A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)

The purpose of this study is to evaluate the long-term efficacy and safety of combined formulation of xanomeline tartrate/trospium chloride in an immediate release (IR) capsule...

Sponsor: Bristol-Myers SquibbEnrolling: 60020 locations
Alzheimer DiseaseAgitation
RECRUITINGPhase 3NCT06947941

A Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis Associated With Alzheimer's...

The purpose of this study is to evaluate KarXT + KarX-EC as a treatment for psychosis associated with Alzheimer's disease.

Sponsor: Bristol-Myers SquibbEnrolling: 32520 locations
Alzheimer DiseasePsychosis
RECRUITINGNCT07361289

A Study to Assess the Real-World Effectiveness of Mavacamten in Adult Patients With Obstructive Hypertrophic...

The purpose of this study is to assess the effectiveness of mavacamten treatment in Chinese adults with symptomatic obstructive hypertrophic cardiomyopathy (HCM) in real-world...

Sponsor: Bristol-Myers SquibbEnrolling: 50015 locations
Hypertrophic Cardiomyopathy
RECRUITINGNCT06551129

Real-world Patient Reported Outcomes Among Patients Treated With Camzyos

This real-world study will assess changes in health status among participants with symptomatic obstructive hypertrophic cardiomyopathy who are treated with mavacamten in the real...

Sponsor: Bristol-Myers SquibbEnrolling: 1181 location
Obstructive Hypertrophic Cardiomyopathy
RECRUITINGNCT07383025

Mavacamten Post-marketing Surveillance in Patients With Obstructive Hypertrophic Cardiomyopathy in Japan

The purpose of this study is to assess the real-world effectiveness and safety of mavacamten in patients with obstructive hypertrophic cardiomyopathy (HCM) receiving mavacamten in...

Sponsor: Bristol-Myers SquibbEnrolling: 2001 location
Obstructive Hypertrophic Cardiomyopathy (oHCM)
RECRUITINGNCT05489705

A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal...

This registry evaluates patient characteristics, real-world treatment patterns, and short- and long-term outcomes in a population of patients in the United States and Europe with...

Sponsor: Bristol-Myers SquibbEnrolling: 170020 locations
Obstructive Hypertrophic Cardiomyopathy
RECRUITINGPhase 3NCT06951698

A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder

The purpose of this study is to evaluate the efficacy and safety of KarXT for the treatment of manic episodes in Bipolar-I Disorder

Sponsor: Bristol-Myers SquibbEnrolling: 27420 locations
Bipolar-I Disorder With Mania or Mania With Mixed Features
RECRUITINGPhase 3NCT06929273

A Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-3)

This is a phase 3, open-label extension study to assess the long-term safety of KarXT for the treatment of mania or mania with mixed features in Bipolar-I disorder (BP-I) The...

Sponsor: Bristol-Myers SquibbEnrolling: 45020 locations
Bipolar Disorder Type I With Mania
RECRUITINGPhase 3NCT07288567

A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Schizophrenia in Adolescents (EMERGENT TEEN)

The purpose of this study is to evaluate the efficacy and safety of KarXT for treatment of Schizophrenia in adolescents.

Sponsor: Bristol-Myers SquibbEnrolling: 16620 locations
Schizophrenia
RECRUITINGPhase 4NCT07221877

A Study to Evaluate the Effect of KarXT on Urological Safety

The purpose of this study is to characterize the effect of KarXT on voiding dynamics and urological safety in participants with DSM-5 schizophrenia.

Sponsor: Bristol-Myers SquibbEnrolling: 6013 locations
Schizophrenia
RECRUITINGPhase 1NCT07061288

A Study to Evaluate the Safety, Tolerability, and PK of an Injectable Form of KarXT

A study to evaluate the safety, tolerability, and PK of an injectable form of KarXT in participants with schizophrenia

Sponsor: Bristol-Myers SquibbEnrolling: 1168 locations
Schizophrenia
RECRUITINGNCT07379827

Effectiveness and Adverse-effect Switch Evaluation of Xanomeline and Trospium Chloride (KarXT)

The purpose of this study is to describe real-world treatment patterns, effectiveness and adverse events of adults diagnosed with schizophrenia that have initiated xanomeline and...

Sponsor: Bristol-Myers SquibbEnrolling: 150020 locations
Schizophrenia
RECRUITINGPhase 1NCT07171983

A Study to Evaluate the Safety, Tolerability, and Drug Levels of BMS-986454 in Participants With Rheumatoid Arthritis

The purpose of this study is to evaluate the safety, tolerability, and drug levels of BMS-986454 in participants with Rheumatoid Arthritis

Sponsor: Bristol-Myers SquibbEnrolling: 469 locations
Rheumatoid Arthritis
RECRUITINGNCT07271069

Effectiveness of Ozanimod in Patients With Steroid-Dependent Ulcerative Colitis

The purpose of this study is to evaluate the effectiveness and safety of ozanimod vs azathioprine for the treatment of ulcerative colitis (UC) in real-world clinical practice in...

Sponsor: Bristol-Myers SquibbEnrolling: 15018 locations
Ulcerative Colitis (UC)
RECRUITINGPhase 3NCT06979453

A Study to Evaluate the Efficacy, Safety, and Drug Levels of Deucravacitinib (BMS-986165) in Adolescent Participants...

The purpose of this study is to evaluate the efficacy, safety, and drug levels of Deucravacitinib (BMS-986165) in adolescent participants with moderate to severe plaque psoriasis

Sponsor: Bristol-Myers SquibbEnrolling: 36620 locations
Plaque Psoriasis
RECRUITINGNCT06382987

A Study of the Comparative Effectiveness of Deucravacitinib in Adults With Plaque Psoriasis in Japan (RePhlect)

This is a prospective, observational, real-world study of adult participants in Japan with physician-reported diagnosis of plaque psoriasis treated with deucravacitinib or...

Sponsor: Bristol-Myers SquibbEnrolling: 6002 locations
Plaque Psoriasis
RECRUITINGPhase 3NCT04772079

A Study to Evaluate the Drug Levels, Efficacy and Safety of Deucravacitinib in Children and Adolescent Participants...

The purpose of this pediatric study is to evaluate the drug levels, efficacy and safety of Deucravacitinib in children and adolescent participants aged 4 to \<18 years with...

Sponsor: Bristol-Myers SquibbEnrolling: 15320 locations
Plaque Psoriasis
RECRUITINGNCT05744466

A Real-world Observational Study to Compare Effectiveness of Deucravacitinib Vs Apremilast in Adults With Plaque...

The purpose of this study is to understand the comparative effectiveness of deucravacitinib versus apremilast in adults with plaque psoriasis.

Sponsor: Bristol-Myers SquibbEnrolling: 15001 location
Psoriasis
RECRUITINGPhase 3NCT07116967

Long-Term Safety Study of Deucravacitinib Versus Ustekinumab in Participants With Psoriasis (PRAGMATYK)

A study to evaluate the long-term safety of Deucravacitinib versus Ustekinumab in participants with psoriasis

Sponsor: Bristol-Myers SquibbEnrolling: 304020 locations
Plaque Psoriasis
RECRUITINGPhase 1 / Phase 2NCT06481306

A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease

The purpose of this study is to evaluate the safety and tolerability, pharmacokinetics and pharmacodynamics, pH and food effect, and preliminary efficacy of BMS-986470 in healthy...

Sponsor: Bristol-Myers SquibbEnrolling: 18420 locations
Anemia, Sickle CellHealthy Volunteers

How to Approach a Trial Listing

Each trial card above links to a dedicated page with the official ClinicalTrials.gov data plus a plain-English translation of the eligibility criteria. We translate technical terminology (ECOG performance status, hepatic function values, exclusionary lab thresholds) into language that a patient or caregiver can understand, but the original clinical text and the live ClinicalTrials.gov record always govern any actual eligibility decision.

Before contacting a trial site, write down questions for your treating physician using the framework on our 25 Questions guide. Discuss whether the trial fits your treatment plan, what the time commitment looks like, and whether your insurance will cover the standard-of-care portions. Trials are not a substitute for a treatment plan — they are an addition that needs medical guidance to evaluate.

Authoritative Resources

Verify any trial registration directly on ClinicalTrials.gov. For background on the FDA approval pathway that Phase 3 trials feed into, see the FDA drug approval process. For cancer-specific trial guidance, the National Cancer Institute publishes patient-oriented overviews. For global trial registrations beyond the U.S., the WHO ICTRP aggregates registries from around the world.

Frequently Asked Questions

How many clinical trials does Bristol-Myers Squibb have on ClinicalTrials.gov?

Bristol-Myers Squibb has 27 clinical trials registered on the federal ClinicalTrials.gov registry, of which 27 are actively recruiting participants right now. These counts come directly from the ClinicalTrials.gov API and are updated as the registry changes.

What conditions does Bristol-Myers Squibb study?

Bristol-Myers Squibb's registered trials cover 20 conditions on ClinicalTrials.gov, led by Schizophrenia (4 trials), Plaque Psoriasis (4 trials), Alzheimer Disease (2 trials), Obstructive Hypertrophic Cardiomyopathy (2 trials), Lung Cancer (1 trial). The complete condition list appears in the sidebar of this page; each condition links to a page listing every recruiting trial in that area, regardless of sponsor.

How do I join a Bristol-Myers Squibb clinical trial?

Joining a clinical trial is a medical decision that should always involve your treating physician. Each trial page on this site includes the eligibility criteria translated into plain English alongside the official clinical text, plus the contact information that the sponsor has registered with ClinicalTrials.gov. Bring the trial information to your doctor before reaching out — they can review the full inclusion and exclusion criteria against your medical history and help you decide whether to pursue screening.

What does the trial phase mean?

Phase 1 trials test safety and dosing in small groups (often 20–80 healthy volunteers or patients). Phase 2 trials evaluate efficacy and side effects in larger groups (100–300 patients with the target condition). Phase 3 trials confirm efficacy and monitor safety in the largest groups (300–3,000+ patients) and form the basis of an FDA approval submission. Phase 4 studies happen after a treatment is approved, monitoring long-term safety and effectiveness in real-world use. Some trials register without a phase — common for device, behavioral, or observational studies.

Where does this trial data come from?

All trial data is pulled directly from the ClinicalTrials.gov API v2, the official federal trial registry maintained by the National Library of Medicine at NIH. Under FDAAA 801, most U.S. drug and device trials are required to register, making ClinicalTrials.gov the most comprehensive source. Sponsors are responsible for keeping their listings current; trial status can shift between data refreshes.

How This Sponsor Page Is Built

Every count on this page is derived directly from ClinicalTrials.gov API v2 records. Trial counts include all trials currently registered to this sponsor; the recruiting count reflects trials with status "Recruiting" or equivalent. Plain-English eligibility translations on each linked trial page preserve the original clinical text alongside an accessible version. Read the full methodology for the data pipeline and limitations.

Source: ClinicalTrials.gov API v2, maintained by the National Library of Medicine at NIH. Public domain. Cite as: "TrialFinderData. Data: ClinicalTrials.gov."

Medical disclaimer: This page is informational, not medical advice. Talk to your doctor about whether a clinical trial is right for you.

Last updated 2026-06-26 · 27 trials tracked for Bristol-Myers Squibb.