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Cancer Institute and Hospital, Chinese Academy of Medical Sciences

15 clinical trials · 15 recruiting · OTHER

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

Trials by Cancer Institute and Hospital, Chinese Academy of Medical Sciences

RECRUITINGNCT07478809

A Retrospective Real-World Study Based on RATIONALE-307

The study aims to retrospectively collect long-term survival data from patients who received first-line tislelizumab combined with chemotherapy in the RATIONALE-307 trial, in...

Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical SciencesEnrolling: 1091 location
NSCLC (Advanced Non-small Cell Lung Cancer)
RECRUITINGNCT07026669

A Multi-omics Sequencing-based Model for Predicting Efficacy and Dynamic Monitoring of Treatment in Small Cell Lung...

Lung cancer is one of the malignant tumors with the highest incidence and mortality rates globally, with small cell lung cancer (SCLC) accounting for approximately 15%. SCLC is...

Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical SciencesEnrolling: 401 location
Small Cell Lung Cancer
RECRUITINGPhase 2NCT06793813

Cadonilimab in Patients (Pts) with Advanced Non-small Cell Lung Cancer (NSCLC)

This phase II trial studies how well cadonilimab combined with Bevacizumab and docetaxel work in treating patients with non-squamous and stage IV non-small cell lung cancer....

Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical SciencesEnrolling: 441 location
Stage IVB Lung CancerNon-Squamous
RECRUITINGEarly Phase 1NCT07298239

An Exploratory Clinical Study Evaluating the Safety and Efficacy of Allogeneic CAR-NK Cell Therapy for Metastatic...

This study introduces a new treatment approach for metastatic castration-resistant prostate cancer, a stage of disease that remains difficult to manage with current therapies....

Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical SciencesEnrolling: 151 location
Prostate Cancer Castration-resistant Prostate Cancer
RECRUITINGNCT06277180

68Ga-TCR-FAPI PET/CT Guided Precision Surgery for MTC

This is a phase II clinical trial to evaluate the capability of 68Ga-labeled targeted covalent radiopharmaceutical (TCR) fibroblast activation protein inhibitor (FAPI) PET/CT to...

Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical SciencesEnrolling: 501 location
Medullary Thyroid CancerPrositron Emission TomographyFibroblast Activation Protein Inhibitor+1
RECRUITINGPhase 3NCT06082180

A Prospective, Open-label, Multicenter, Randomized Controlled Phase III Study of Prophylactic Central Neck Dissection...

papillary thyroid carcinoma (PTC) is the most common thyroid cancer and has a good prognosis. Surgery is the primary treatment for PTC, and occult lymph node metastasis is not...

Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical SciencesEnrolling: 11991 location
Thyroid CancerRecurrence
RECRUITINGPhase 3NCT07383246

CTR-FAPI-guided Precision Surgery for Newly Diagnosed MTC

This is a multicenter, randomized, open-label, non-inferiority Phase III clinical trial, aims to compare 68Ga-CTR-FAPI PET-CT-guided surgery to investigator-chosen surgical...

Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical SciencesEnrolling: 1501 location
Medullary Thyroid Carcinoma
RECRUITINGNCT06417892

Fruquintinib and Albumin-paclitaxel Combined With or Without PD-1 Antibody in 2nd-line Treatment of G/GEJ Adenocarcinoma

To explore the efficacy and safety of fruquintinib and albumin-paclitaxel combined with or without PD-1 antibody in the second-line treatment of advanced gastric/gastroesophageal...

Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical SciencesEnrolling: 601 location
Gastric Cancer
RECRUITINGPhase 2NCT06421376

Induction Chemoimmunotherapy Combined With Chemoradiotherapy in Esophageal Cancer

Although unprecedented advances have been made in the field of esophageal cancer in recent decades, the prognosis for patients with locally advanced esophageal squamous cell...

Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical SciencesEnrolling: 603 locations
Esophageal CancerImmunotherapyInduction Therapy+2
RECRUITINGPhase 2 / Phase 3NCT05504265

Perioperative Analgesia Modes in Minimally Invasive Esophagectomy

This study was designed to compare analgesic efficacy and safety of different perioperative analgesic modes in minimally invasive esophagectomy for esophageal cancer.

Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical SciencesEnrolling: 1021 location
Esophageal CancerPerioperative AnalgesiaNSAIDs+2
RECRUITINGPhase 3NCT06086457

PD-1 Inhibitor Plus Chemotherapy With or Without Radiotherapy in Patients With Metastatic Esophageal Cancer

The treatment efficacy for stage IVb esophageal cancer has been improved through chemotherapy combined with immunotherapy recently. On this basis, the investigators intend to...

Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical SciencesEnrolling: 4361 location
Esophageal Neoplasms
RECRUITINGPhase 2NCT06170710

Postoperative CCRT Followed by Immunotherapy in High-Risk LA HNSCC

This trial aims to evaluate whether the addition of anti-PD-1 antibody to adjuvant postoperative chemoradiotherapy could improve disease free survival in patients with high-risk...

Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical SciencesEnrolling: 1731 location
Head and Neck Squamous Cell Carcinoma
RECRUITINGPhase 2NCT06543069

Sintilimab, Bevacizumab, Pemetrexed, and Cisplatin for Unresectable MPeM

To explore the efficacy and safety of sintilimab, bevacizumab combined with pemetrexed and cisplatin in the treatment of malignant peritoneal mesothelioma, and to explore the...

Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical SciencesEnrolling: 281 location
Malignant Peritoneal Mesothelioma, Advanced
RECRUITINGPhase 2NCT05188859

First Line Sintilimab Combined With Anlotinib and Platinum Doublet Chemotherapy in Malignant Pleural Mesothelioma

This study is a single-arm, open-lable, single-center phase II clinical trial for patients with advanced or metastatic pleural mesothelioma. The aim of this study was to observe...

Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical SciencesEnrolling: 292 locations
Mesothelioma, MalignantMesothelioma, Malignant PleuralMesothelioma Malignant Advanced
RECRUITINGPhase 2NCT07187193

Efficacy and Safety of Low-Dose Cytarabine Combined With Thalidomide in Adult Patients With Untreated LCH

Treatment of Adult Patients with Newly Diagnosed Langerhans Cell Histiocytosis (LCH) Using a Low-Dose Cytarabine Combined with Thalidomide Regimen.

Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical SciencesEnrolling: 501 location
Langerhans Cell Histiocytosis