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City of Hope Medical Center

13 clinical trials · 13 recruiting · OTHER

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

Trials by City of Hope Medical Center

RECRUITINGPhase 2NCT05672355

A Vaccine Booster (GEO-CM04S1) for the Prevention of COVID-19 in Patients With Chronic Lymphocytic Leukemia

This phase II trial compares the effect of the GEO-CM04S1 vaccine with the current standard of care vaccine in preventing COVID-19 infections in patients with chronic lymphocytic...

Sponsor: City of Hope Medical CenterEnrolling: 801 location
Chronic Lymphocytic LeukemiaCOVID-19 Infection
RECRUITINGNCT06388967

Pancreatic Cancer Detection Consortium

This study aims to prospective validate an exosome-based miRNA signature for noninvasive and early detection of pancreatic ductal adenocarcinoma.

Sponsor: City of Hope Medical CenterEnrolling: 200011 locations
Pancreatic CancerPancreatic CarcinomaPancreatic Adenocarcinoma+10
RECRUITINGPhase 2NCT06059391

CMV-MVA Triplex Vaccination in HLA-Matched Related Stem Cell Donors for the Prevention of CMV Infection in Patients...

This phase II clinical trial tests how well the cytomegalovirus-modified vaccinica Ankara (CMV-MVA) Triplex vaccine given to human leukocyte antigens (HLA) matched related stem...

Sponsor: City of Hope Medical CenterEnrolling: 2163 locations
Acute Lymphoblastic LeukemiaAcute Myeloid LeukemiaChronic Lymphocytic Leukemia+7
RECRUITINGNCT04670874

Quality of Life in Cutaneous Lymphoma Patients Using the Skindex29

This study assesses the quality of life in patients with cutaneous lymphoma diagnosis as it relates to their personal, clinical, and therapeutic information using the Skindex29...

Sponsor: City of Hope Medical CenterEnrolling: 12501 location
Cutaneous Lymphoma
RECRUITINGPhase 2NCT04484012

Modified Immune Cells (CD19 CAR T Cells) and Acalabrutinib for the Treatment of Relapsed or Refractory Mantle Cell...

This phase II trial investigates the side effects of CD19 chimeric antigen receptor (CAR) T cells and acalabrutinib, and to see how well they work in treating patients with mantle...

Sponsor: City of Hope Medical CenterEnrolling: 361 location
Recurrent Mantle Cell LymphomaRefractory Mantle Cell Lymphoma
RECRUITINGPhase 2NCT06440850

Vemurafenib and Cobimetinib for the Treatment of Patients With High Risk Differentiated Thyroid Carcinoma With...

This phase II trial tests how well vemurafenib and cobimetinib work in treating patients with high risk differentiated thyroid carcinoma with BRAFV600E mutation, in preparation...

Sponsor: City of Hope Medical CenterEnrolling: 211 location
Thyroid Gland Follicular CarcinomaThyroid Gland Oncocytic CarcinomaThyroid Gland Papillary Carcinoma
RECRUITINGNCT06490003

Predicting Postoperative Chemotherapy Efficacy in Patients With Esophageal Squamous Cell Carcinoma

Esophageal cancer remains a disease with a poor prognosis. Chemotherapy is an important part of its treatment, but there are cases in which chemotherapy is ineffective. The...

Sponsor: City of Hope Medical CenterEnrolling: 1501 location
Esophageal Squamous Cell CarcinomaChemotherapy EffectDNA Methylation
RECRUITINGPhase 1NCT05363111

Radioimmunotherapy (111Indium/225Actinium-DOTA-daratumumab) for the Treatment of Relapsed/Refractory Multiple Myeloma

This phase I trial tests the safety, side effects, and best dose of actinium Ac 225-DOTA-daratumumab (225Ac-DOTA-daratumumab) in combination with daratumumab and indium In...

Sponsor: City of Hope Medical CenterEnrolling: 151 location
Recurrent Plasma Cell MyelomaRefractory Plasma Cell Myeloma
RECRUITINGPhase 2NCT04508790

Leflunomide, Pomalidomide, and Dexamethasone for the Treatment of Relapsed or Refractory Multiple Myeloma

This phase II trial studies how well leflunomide, pomalidomide, and dexamethasone work for the treatment of multiple myeloma that has come back (relapsed) or does not respond to...

Sponsor: City of Hope Medical CenterEnrolling: 291 location
Recurrent Plasma Cell MyelomaRefractory Plasma Cell Myeloma
RECRUITINGPhase 2NCT05672108

Phase II Trial of Lung Chemoemobolization

This phase II trial evaluates how well transarterial chemoembolization (TACE) works for treating patients with non-small cell lung cancer or lung metastases. TACE is a minimally...

Sponsor: City of Hope Medical CenterEnrolling: 302 locations
Lung Non-Small Cell CarcinomaMediastinal NeoplasmPleural Neoplasm+4
RECRUITINGPhase 2NCT05722288

Time-Restricted Eating Versus Nutritional Counseling for the Reduction of Radiation or Chemoradiation Tx Side Effects...

This phase II trial studies how well time-restricted eating works in reducing side effects of radiation or chemoradiation side effects when compared to nutritional counseling...

Sponsor: City of Hope Medical CenterEnrolling: 601 location
Localized Prostate CarcinomaLocally Advanced Cervical CarcinomaLocally Advanced Rectal Carcinoma+15
RECRUITINGPhase 1 / Phase 2NCT07061574

A Randomized Phase 1/2 Trial of Low Dose Anti-thymocyte Globulin (ATG) With Subsequent Adalimumab or Verapamil in New...

This multi-center randomized controlled trial will assess the safety and efficacy of ATG followed by either adalimumab or verapamil in preserving insulin secretion 2 years from...

Sponsor: City of Hope Medical CenterEnrolling: 12011 locations
Type 1 DiabetesNew Onset
RECRUITINGEarly Phase 1NCT04380831

TBI Using IMRT and Cyclophosphamide Prior to Stem Cell Transplant for the Treatment of Severe Systemic Sclerosis

This early phase I trial studies the side effects and feasibility of total body irradiation using intensity modulation radiation therapy (IMRT) when given in combination with...

Sponsor: City of Hope Medical CenterEnrolling: 151 location
Systemic Scleroderma