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Updated May 2026 · ClinicalTrials.gov

Hospices Civils de Lyon

43 clinical trials · 43 recruiting · OTHER

Hospices Civils de Lyon has 43 clinical trials registered on ClinicalTrials.gov, with 43 actively recruiting participants. The trials listed below cover 20 conditions across the phases listed in the sidebar. Always discuss any specific trial with your physician before contacting a study site.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About Hospices Civils de Lyon\'s Trial Portfolio

Hospices Civils de Lyon is a non-industry sponsor (academic medical center, hospital, foundation, or research network). Non-industry sponsors often investigate novel approaches, rare conditions, and behavioral or surgical interventions that commercial sponsors may not prioritize.

43 of Hospices Civils de Lyon's 43 registered trials are currently recruiting — roughly 100% of the portfolio. A high recruiting share usually points to an active research pipeline with multiple programs at the enrollment stage.

Hospices Civils de Lyon's research footprint spans Cystic Fibrosis (3 trials), Epilepsy (2), and pancreatic-ductal-adenocarcinoma-mpdac (1) as the top three conditions. The full condition list, sorted by trial count, is in the sidebar.

is the largest single phase in Hospices Civils de Lyon's portfolio at 63% of registered trials. The full phase breakdown appears in the sidebar.

Trials by Hospices Civils de Lyon

RECRUITINGNCT07144917

Immunoparalysis After Pancreaticoduodenectomy

By 2030, pancreatic adenocarcinoma could become the second leading cause of cancer-related death in France. To date, Pancreaticoduodenectomy (PD) is the standard treatment for...

Sponsor: Hospices Civils de LyonEnrolling: 1004 locations
Pancreatic Ductal Adenocarcinoma (mPDAC)Pancreatic Head TumourPancreatic Fistula
RECRUITINGNCT04714957

PITCHER (Peritoneal Carcinomatosis Heterogeneity)

How epigenetic deregulation affects gene expression patterns in subclones of the same tumor is poorly known. Peritoneal Carcinomatosis (PC) is a condition in which multiple...

Sponsor: Hospices Civils de LyonEnrolling: 201 location
Secondary Peritoneal CancersColorectal CancerOvarian Cancer
RECRUITINGPhase 2NCT06790706

IMMUNORARE5: A National Platform of 5 Academic Phase II Trials Coordinated by Lyon University Hospital to Assess the...

Immune checkpoint inhibitors (ICI) have revolutionized the management of advanced cancers. However, most rare cancers have been excluded from this progress due to the lack of...

Sponsor: Hospices Civils de LyonEnrolling: 15415 locations
Peritoneal MesotheliomaGestational Trophoblastic TumorThymoma and Thymic Carcinoma+3
RECRUITINGNCT06884722

Brain Mechanisms of Social Perception in Parkinson's Disease

Social cognition is a complex process that enables humans to interpret social information and behave appropriately in a social environment. Social cognition can be impaired in...

Sponsor: Hospices Civils de LyonEnrolling: 831 location
Social Perception in Parkinson's Disease
RECRUITINGNCT06967935

Sleep and Rehearsal-Driven Memory in Epilepsy

Memory consolidation transforms unstable memory traces into lasting representations, a process enhanced by both sleep and rehearsal during learning. Rehearsal is thought to...

Sponsor: Hospices Civils de LyonEnrolling: 201 location
EpilepsyMemory Consolidation
RECRUITINGNCT06545708

Music Perception in SeLECTs

Self-limited epilepsy with centrotemporal spikes (SeLECTS) is the most frequent epilepsy syndrome in children between the ages of 4 and 13 years. SeLECTS is associated in 15 to...

Sponsor: Hospices Civils de LyonEnrolling: 1002 locations
Rolandic Epilepsy
RECRUITINGNCT05285059

Implicit Learning in Epileptic Children

Epileptic children suffer from impairments in various learning and memory tasks. Yet, no study investigated implicit learning in epileptic children. Implicit learning is not only...

Sponsor: Hospices Civils de LyonEnrolling: 403 locations
Epilepsy
RECRUITINGNCT04620642

Lyon Registry of Stroke Treated by Thrombolysis or Thrombectomy

This observational study as an objective of characterizing the population of patients treated within the neurovascular unit of the Pierre Wertheimer hospital (Hospices Civils de...

Sponsor: Hospices Civils de LyonEnrolling: 45001 location
Ischemic Stroke
RECRUITINGNCT07038239

Genotype/Phenotype Correlation of MORC2 Mutations

The Microrchidia CW-type zinc finger 2 (MORC2) gene encodes a protein expressed in all tissues and enriched in the brain. It is involved in Charcot-Marie-Tooth disease, with mire...

Sponsor: Hospices Civils de LyonEnrolling: 4512 locations
Charcot Marie Tooth DiseaseDIFGANDevelopmental Delay (Disorder)+2
RECRUITINGNCT03918421

Immunoglobulin M (IgM)-Anti-myelin-associated-glycoprotein(MAG) Peripheral Neuropathy Study

There is no international consensus regarding how to assess and treat patients with immunoglobulin M (IgM)-anti-myelin-associated-glycoprotein (MAG) monoclonal gammopathy...

Sponsor: Hospices Civils de LyonEnrolling: 452 locations
Immunoglobin M Anti-myelin-associated-glycoprotein Peripheral Neuropathy
RECRUITINGNCT07254338

Exploration of Metabolome in Patients With Interstitial Lung Disease and Pulmonary Hypertension With or Without...

Fibrosing interstitial lung diseases (FILDs) encompass a group of rare diseases characterized by progressive pulmonary fibrosis leading to respiratory failure. Current treatments...

Sponsor: Hospices Civils de LyonEnrolling: 801 location
Interstitial Lung DiseasePrecapillar Pulmonary Hypertension
RECRUITINGNCT05192707

Transcutaneous Oxygen Pressure (TcPO2) Determination.

Upper limb arterial disease is a rare condition compared to lower limb arterial disease. In the lower limb, chronic limb ischemia (CLI) is characterized by an intractable pain or...

Sponsor: Hospices Civils de LyonEnrolling: 601 location
Peripheral Arterial Diseases
RECRUITINGNCT06477042

Act on Quality of Life in Patients With aortIc Stenosis

Aortic stenosis (AS) is a degenerative process affecting the aortic valve that leads to sclerosis of the valve and limits its opening during cardiac contractions. The prognosis is...

Sponsor: Hospices Civils de LyonEnrolling: 2404 locations
Severe Aortic Stenosis
RECRUITINGNCT06713889

Identifying Biological Markers of Cardiovascular Events in Patients With Aortic Stenosis or TAVI

Aortic stenosis, a common cardiovascular disease, is pathophysiologically associated with a chronic inflammatory myocardial reaction and fibrosis leading to cardiac dysfunction...

Sponsor: Hospices Civils de LyonEnrolling: 1252 locations
Aortic Stenosis
RECRUITINGNCT06878690

Sleep Disorders in Specific Learning Disabilities

Specific learning disorders, or SLD, are cognitive and behavioral conditions that emerge during childhood and involve significant difficulties in acquiring and performing specific...

Sponsor: Hospices Civils de LyonEnrolling: 10001 location
Specific Learning DisabilitySleepSleep Disorder (Disorder)+1
RECRUITINGNCT04279158

Attention Modulation of Local and Global Inhibition Mechanisms

Human behavior is both flexible and adapted to the environmental context through inhibition capabilities; the investigator control the subject's behavior by repressing...

Sponsor: Hospices Civils de LyonEnrolling: 1201 location
Optical Phenomena
RECRUITINGNCT02812537

Clinical and Social Trajectories of Children and Adolescents With Disruptive Behavior

Conduct disorders are defined as "repetitive and persistent pattern of behavior in which the basic rights of others or major age-appropriate norms are violated". So defined, these...

Sponsor: Hospices Civils de LyonEnrolling: 5001 location
Disruptive Behavior Disorder
RECRUITINGNCT05682417

Impact of Body Schema Distortion on Remission and Weight Regain in Anorexia Nervosa

Anorexia nervosa is a predominantly female eating disorder that most often appears in adolescence. The latter leads to strict and voluntary food deprivation for several months or...

Sponsor: Hospices Civils de LyonEnrolling: 421 location
Anorexia Nervosa
RECRUITINGNCT05413759

RhEumatoid Arthritis MEDIcation Adherence

Rheumatoid arthritis (RA) is a public health issue because of its frequency, its functional consequences, the risk of morbidity and mortality and the costs incurred. A...

Sponsor: Hospices Civils de LyonEnrolling: 2002 locations
Rheumatoid Arthritis
RECRUITINGNCT06435468

Biocollection of Rare Pediatric-onset of Autoimmune and Autoinflammatory Diseases

Rare diseases are defined as those that affect one person in 2,000, or around three million people in France. The majority of rare diseases are caused by genetics and tend to be...

Sponsor: Hospices Civils de LyonEnrolling: 40013 locations
Systemic LupusAutoimmune DiseasesAutoinflammatory Disease+1
RECRUITINGNCT03915262

Exocrine Pancreatic Insufficiency's Prevalence in Active Crohn's Disease

This study aims to assess the prevalence of exocrine pancreatic insufficiency (EPI) in a population of patients with active Crohn's disease. Studies already describe a prevalence...

Sponsor: Hospices Civils de LyonEnrolling: 501 location
Crohn Disease
RECRUITINGNCT03290456

Evaluate the Remission MAINtenance Using Extended Administration of Prednisone in Systemic Anti-neutrophil Cytoplasmic...

Immunosuppressive therapy of granulomatosis with polyangiitis (GPA, Wegener's) and microscopic polyangiitis (MPA) has transformed the outcome from death to a strong likelihood of...

Sponsor: Hospices Civils de LyonEnrolling: 14620 locations
Granulomatosis With Polyangitis
RECRUITINGNCT05783466

Dairy Lipids and Cardiometabolic Risk

It is a randomized parallel arm intervention study in adults with severe obesity. The objective is to demonstrate that within a dietary handling for weight loss, the daily...

Sponsor: Hospices Civils de LyonEnrolling: 752 locations
Morbid Obesity
RECRUITINGNCT06370962

Circadian Rhythm Disorders in Children With Cystic Fibrosis Under CFTR (Cystic Fibrosis Transmembrane Conductance...

Cystic fibrosis (CF) is a rare disease affecting one out of 4,500 newborns in France (INSERM 2021). Despite major advances in patient care over the past two decades, with...

Sponsor: Hospices Civils de LyonEnrolling: 1803 locations
Cystic Fibrosis
RECRUITINGNCT06599892

CF Organization of Care in the Era of Highly Effective Modulator.

Recently, triple therapy has made it possible to extend access to these modulators to a large proportion of the patient population, with spectacular clinical benefits, provided...

Sponsor: Hospices Civils de LyonEnrolling: 50001 location
Cystic Fibrosis
RECRUITINGNCT06507956

Physical Activity Profile and Sedentary Behaviour in Adults With Cystic Fibrosis

Cystic fibrosis is a multisystem genetic disease whose severity, linked to the nature of the mutation in the gene carried, is linked to respiratory impairment, which determines...

Sponsor: Hospices Civils de LyonEnrolling: 2701 location
Cystic Fibrosis
RECRUITINGNCT06586138

Study of Psychological, Sociological and Professional Factors Associated With Maintenance of Wakefulness Test

The predictors of objective impaired alertness assessed by Maintenance of Wakefulness Tests (MWT) are poorly understood. Identifying such predictors are essential from a clinical...

Sponsor: Hospices Civils de LyonEnrolling: 2001 location
NarcolepsyObstructive Sleep Apnea (OSA)
RECRUITINGNCT04271397

Immunological Biomarkers in Tuberculosis Management

Tuberculosis (TB) is the leading cause of death by infectious disease in the world, responsible for 1.6 million deaths in 2017. The treatment of active TB requires at least a...

Sponsor: Hospices Civils de LyonEnrolling: 601 location
TuberculosisTuberculosis Infection
RECRUITINGPhase 4NCT05841758

Hydroxychloroquine as a Steroid-sparing Agent in Extrapulmonary Sarcoidosis

Sarcoidosis is a systemic granulomatous disease of unknown aetiology, mainly affecting the lungs and lymphatics. It affects people worldwide (incidence, 4.7-64/100000; prevalence,...

Sponsor: Hospices Civils de LyonEnrolling: 14020 locations
Sarcoidosis, Pulmonary
RECRUITINGNCT06047093

Fine Needle Aspiration (FNA) Evaluation of the Intrahepatic HBV Reservoir and Its Immunological Characteristics in...

Two hundred and ninety-six million people worldwide are chronically infected with the hepatitis B virus (HBV), with around 750,000 deaths each year linked to the development of...

Sponsor: Hospices Civils de LyonEnrolling: 1001 location
Chronic Hepatitis b

Showing 30 of 43 trials. The remainder are accessible through individual condition pages or directly on ClinicalTrials.gov.

How to Approach a Trial Listing

Each trial card above links to a dedicated page with the official ClinicalTrials.gov data plus a plain-English translation of the eligibility criteria. We translate technical terminology (ECOG performance status, hepatic function values, exclusionary lab thresholds) into language that a patient or caregiver can understand, but the original clinical text and the live ClinicalTrials.gov record always govern any actual eligibility decision.

Before contacting a trial site, write down questions for your treating physician using the framework on our 25 Questions guide. Discuss whether the trial fits your treatment plan, what the time commitment looks like, and whether your insurance will cover the standard-of-care portions. Trials are not a substitute for a treatment plan — they are an addition that needs medical guidance to evaluate.

Authoritative Resources

Verify any trial registration directly on ClinicalTrials.gov. For background on the FDA approval pathway that Phase 3 trials feed into, see the FDA drug approval process. For cancer-specific trial guidance, the National Cancer Institute publishes patient-oriented overviews. For global trial registrations beyond the U.S., the WHO ICTRP aggregates registries from around the world.

Frequently Asked Questions

How many clinical trials does Hospices Civils de Lyon have on ClinicalTrials.gov?

Hospices Civils de Lyon has 43 clinical trials registered on the federal ClinicalTrials.gov registry, of which 43 are actively recruiting participants right now. These counts come directly from the ClinicalTrials.gov API and are updated as the registry changes.

What conditions does Hospices Civils de Lyon study?

Hospices Civils de Lyon's registered trials cover 20 conditions on ClinicalTrials.gov, led by Cystic Fibrosis (3 trials), Epilepsy (2 trials), pancreatic-ductal-adenocarcinoma-mpdac (1 trial), pancreatic-head-tumour (1 trial), Pancreatic Fistula (1 trial). The complete condition list appears in the sidebar of this page; each condition links to a page listing every recruiting trial in that area, regardless of sponsor.

How do I join a Hospices Civils de Lyon clinical trial?

Joining a clinical trial is a medical decision that should always involve your treating physician. Each trial page on this site includes the eligibility criteria translated into plain English alongside the official clinical text, plus the contact information that the sponsor has registered with ClinicalTrials.gov. Bring the trial information to your doctor before reaching out — they can review the full inclusion and exclusion criteria against your medical history and help you decide whether to pursue screening.

What does the trial phase mean?

Phase 1 trials test safety and dosing in small groups (often 20–80 healthy volunteers or patients). Phase 2 trials evaluate efficacy and side effects in larger groups (100–300 patients with the target condition). Phase 3 trials confirm efficacy and monitor safety in the largest groups (300–3,000+ patients) and form the basis of an FDA approval submission. Phase 4 studies happen after a treatment is approved, monitoring long-term safety and effectiveness in real-world use. Some trials register without a phase — common for device, behavioral, or observational studies.

Where does this trial data come from?

All trial data is pulled directly from the ClinicalTrials.gov API v2, the official federal trial registry maintained by the National Library of Medicine at NIH. Under FDAAA 801, most U.S. drug and device trials are required to register, making ClinicalTrials.gov the most comprehensive source. Sponsors are responsible for keeping their listings current; trial status can shift between data refreshes.

How This Sponsor Page Is Built

Every count on this page is derived directly from ClinicalTrials.gov API v2 records. Trial counts include all trials currently registered to this sponsor; the recruiting count reflects trials with status "Recruiting" or equivalent. Plain-English eligibility translations on each linked trial page preserve the original clinical text alongside an accessible version. Read the full methodology for the data pipeline and limitations.

Source: ClinicalTrials.gov API v2, maintained by the National Library of Medicine at NIH. Public domain. Cite as: "TrialFinderData. Data: ClinicalTrials.gov."

Medical disclaimer: This page is informational, not medical advice. Talk to your doctor about whether a clinical trial is right for you.

Last updated 2026-05-08 · 43 trials tracked for Hospices Civils de Lyon.

The this entity record above pulls directly from the NIH ClinicalTrials.gov registry. What follows is the per-entity context — how this entity sits in the broader U.S. clinical trials and research registries distribution and which underlying factors drive the headline numbers.

Every number on this page links back to the NIH ClinicalTrials.gov registry; the methodology page describes the inputs, refresh cadence, and known limitations of the underlying data product.

For readers using this page as a decision input, the related-entity pages elsewhere on the site provide the comparison set. The most useful comparison for this entity is typically a peer within active and historical clinical trials with similar size, similar exposure, or similar geography — not the national-level summary alone.