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TrialFinderData is for informational purposes only and does not provide medical advice. Always talk to your doctor.

Updated June 2026 · ClinicalTrials.gov

Icahn School of Medicine at Mount Sinai

Reviewed by TrialFinderData Editorial Team · Updated

21 clinical trials · 21 recruiting · OTHER

Icahn School of Medicine at Mount Sinai has 21 clinical trials registered on ClinicalTrials.gov, with 21 actively recruiting participants. The trials listed below cover 20 conditions across the phases listed in the sidebar. Always discuss any specific trial with your physician before contacting a study site.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About Icahn School of Medicine at Mount Sinai\'s Trial Portfolio

Icahn School of Medicine at Mount Sinai is a non-industry sponsor (academic medical center, hospital, foundation, or research network). Non-industry sponsors often investigate novel approaches, rare conditions, and behavioral or surgical interventions that commercial sponsors may not prioritize.

21 of Icahn School of Medicine at Mount Sinai's 21 registered trials are currently recruiting — roughly 100% of the portfolio. A high recruiting share usually points to an active research pipeline with multiple programs at the enrollment stage.

Icahn School of Medicine at Mount Sinai's research footprint spans Bulimia Nervosa (3 trials), Multiple Sclerosis (2), and Traumatic Brain Injury (2) as the top three conditions. The full condition list, sorted by trial count, is in the sidebar.

Not Applicable is the largest single phase in Icahn School of Medicine at Mount Sinai's portfolio at 52% of registered trials. The full phase breakdown appears in the sidebar.

Trials by Icahn School of Medicine at Mount Sinai

RECRUITINGPhase 1 / Phase 2NCT05095207

Abemaciclib in Combination With Bicalutamide for Androgen Receptor-positive, HER2-negative Metastatic Breast Cancer

This is an open label multicenter, Phase IB/II Study of Abemaciclib in Combination with Bicalutamide for Androgen Receptor-positive, HER2-negative Metastatic Breast Cancer

Sponsor: Icahn School of Medicine at Mount SinaiEnrolling: 423 locations
Breast CancerMetastasis
RECRUITINGNCT04615988

Correlation Vitamin D Level to Endocrine Autoimmune Toxicity Due to Immune Checkpoint Inhibitors

The purpose of this research study is to see if the amount of vitamin D in ones blood makes it more or less likely to develop thyroid gland toxicity when being treated with...

Sponsor: Icahn School of Medicine at Mount SinaiEnrolling: 171 location
ThyroidPD-1Cancer
RECRUITINGNCT06992115

A Study of the MIND Diet for Persons With Multiple Sclerosis

This study will assess the impact of a MIND (Mediterranean-DASH Intervention for Neurodegenerative Delay) diet on brain health and MS symptoms. Participants will be randomly...

Sponsor: Icahn School of Medicine at Mount SinaiEnrolling: 1001 location
Multiple Sclerosis
RECRUITINGPhase 1NCT05539729

Vancomycin Study in Multiple Sclerosis (MS)

The overall goal of this study is to elucidate a mechanism by which vancomycin modulates the gut-brain axis in multiple sclerosis (MS). The gut microbiome plays an important role...

Sponsor: Icahn School of Medicine at Mount SinaiEnrolling: 121 location
Multiple Sclerosis
RECRUITINGNCT05933629

Community-based Implementation of Online EmReg

This is a hybrid type III implementation-effectiveness trial; this study design blends elements of implementation and clinical effectiveness research, with the primary aim of...

Sponsor: Icahn School of Medicine at Mount SinaiEnrolling: 501 location
Traumatic Brain InjuryEmotion Regulation
RECRUITINGNCT06766435

Evaluation of the Abbott i-STAT TBI Biomarker Test

According to the Centers for Disease Control and Prevention, approximately 200,000 hospitalizations occurred in 2020 related to Traumatic Brain Injury (TBI), which does not...

Sponsor: Icahn School of Medicine at Mount SinaiEnrolling: 4503 locations
Traumatic Brain Injury
RECRUITINGNCT07094451

Virtual Reality for Pain Control in US-Guided Obstetric Needle Procedures

This is a single-site randomized controlled pilot study at Mount Sinai Hospital evaluating the effect of virtual reality on procedural pain and anxiety in obstetric patients...

Sponsor: Icahn School of Medicine at Mount SinaiEnrolling: 501 location
Procedural Pain
RECRUITINGNCT05160129

Connectomic Deep Brain Stimulation for Obsessive Compulsive Disorder

Deep brain stimulation (DBS) is an effective treatment for people suffering from severe obsessive-compulsive disorder (OCD) whose symptoms have failed to improve after years and...

Sponsor: Icahn School of Medicine at Mount SinaiEnrolling: 221 location
Obsessive Compulsive Disorder (OCD)
RECRUITINGPhase 4NCT03781752

Carboxylesterase 1 Genetic Variation and Methylphenidate in ADHD

The study team will determine the association between d,l-methylphenidate (MPH) therapeutic outcomes in ADHD patients and genetic variants of CES1 and reveal key associations...

Sponsor: Icahn School of Medicine at Mount SinaiEnrolling: 5004 locations
ADHDAttention Deficit Hyperactivity Disorder
RECRUITINGPhase 4NCT03781765

Stimulant vs. Non-stimulant Treatments and Reward Processing in Drug-naive Youth at SUD Risk

The study team will examine the effects of FDA approved stimulant and non-stimulant medications for ADHD, among youth with ADHD and with and without Oppositional Defiant Disorder...

Sponsor: Icahn School of Medicine at Mount SinaiEnrolling: 441 location
ADHDAttention Deficit Hyperactivity Disorder
RECRUITINGPhase 1NCT07542145

MDMA Assisted Therapy for BN

This project will evaluate MDMA Assisted Therapy (MDMA-AT) assisted psychotherapy for the treatment of Bulimia Nervosa (BN) over a 10-week period. Preliminary data suggests that...

Sponsor: Icahn School of Medicine at Mount SinaiEnrolling: 401 location
Bulimia Nervosa
RECRUITINGNCT05995496

Changes in Inhibition and Valuation After Eating

An impaired ability to exert control has been implicated in bulimia nervosa (BN), but this impairment may not represent a stable trait or be the most effective focus for...

Sponsor: Icahn School of Medicine at Mount SinaiEnrolling: 1501 location
Bulimia Nervosa
RECRUITINGNCT05614024

Neurofeedback During Eating for Bulimia Nervosa

The purpose of this study is to examine the effects of noninvasive prefrontal cortex (PFC) neurofeedback during eating in women with bulimia nervosa (BN) using a wearable brain...

Sponsor: Icahn School of Medicine at Mount SinaiEnrolling: 301 location
Bulimia Nervosa
RECRUITINGNCT03718923

FOXP1 Syndrome: The Seaver Autism Center for Research and Treatment is Characterizing FOXP1-related Neurodevelopmental...

FOXP1, also known as Forkhead-box Protein P1, is a transcription factor protein belonging to the FOX gene family. Disruptions in the FOXP1 gene cause a phenotype characterized by...

Sponsor: Icahn School of Medicine at Mount SinaiEnrolling: 501 location
FOXP1Mental Retardation With Language Impairment and With or Without Autistic FeaturesAutism Spectrum Disorder
RECRUITINGNCT06512597

Behavioral Therapy for Crohn's Disease

People living with Crohn's disease (CD) experience psychological and emotional symptoms, in addition to known chronic and disabling physical symptoms, which prevent them from...

Sponsor: Icahn School of Medicine at Mount SinaiEnrolling: 1702 locations
Crohn's Disease
RECRUITINGNCT06001450

Pregnant Women With and Without Crohns Disease to Explore the Role of Plastics and Toxins in Intestinal Inflammation

The PLANET Study aims to determine the impact of microplastics on intestinal inflammation and gut microbiome in order to understand the role of this pollutant on the risk of...

Sponsor: Icahn School of Medicine at Mount SinaiEnrolling: 461 location
Crohns DiseasePregnancyInflammatory Bowel Disease
RECRUITINGNCT06329544

High Fructose Diet, the Gut Microbiome, and Metabolic Health

Americans commonly consume excess amounts of dietary fructose. Added fructose has been shown to have an adverse impact on metabolic health, including increased insulin resistance...

Sponsor: Icahn School of Medicine at Mount SinaiEnrolling: 301 location
MASLDType 2 DiabetesObesity
RECRUITINGPhase 3NCT06960928

Low Dose Sirolimus in People With Post-Acute Sequelae of COVID-19 (PASC) Long COVID-19

The study is conducted in New York, New York at The Cohen Center for Recovery from Complex Chronic Illness at Mount Sinai. This is an IND-exempt, off-label, multi-ascending,...

Sponsor: Icahn School of Medicine at Mount SinaiEnrolling: 801 location
Long COVID-19
RECRUITINGNCT06771167

Building Community Resilience Program

Established in 2021, NYCEAL consists of approximately 40 organizational partners and 120 Community Health Workers (CHWs). Over the next four years (2024-2028), NYCEAL will work...

Sponsor: Icahn School of Medicine at Mount SinaiEnrolling: 1681 location
Resilience, PsychologicalBurnout, PsychologicalStress, Psychological
RECRUITINGNCT06689176

Chlorhexidine Antiseptic Irrigation of the Bowel Segment During Radical Cystectomy and Urinary Diversion

This is a single arm, interventional pilot study of using chlorhexidine irrigation intra-operatively and post-operatively among patients undergoing radical cystectomy with urinary...

Sponsor: Icahn School of Medicine at Mount SinaiEnrolling: 231 location
Bladder CancerUrinary Tract Infection
RECRUITINGPhase 1 / Phase 2NCT06930703

Cannabidiol in Sickle Cell Disease

Randomized, placebo-controlled, double masked, dose finding study of twice daily cannabidiol given at 3 dose levels, 200mg, 400mg, and 600mg, compared to placebo for 4 weeks.

Sponsor: Icahn School of Medicine at Mount SinaiEnrolling: 521 location
Sickle Cell Disease

How to Approach a Trial Listing

Each trial card above links to a dedicated page with the official ClinicalTrials.gov data plus a plain-English translation of the eligibility criteria. We translate technical terminology (ECOG performance status, hepatic function values, exclusionary lab thresholds) into language that a patient or caregiver can understand, but the original clinical text and the live ClinicalTrials.gov record always govern any actual eligibility decision.

Before contacting a trial site, write down questions for your treating physician using the framework on our 25 Questions guide. Discuss whether the trial fits your treatment plan, what the time commitment looks like, and whether your insurance will cover the standard-of-care portions. Trials are not a substitute for a treatment plan — they are an addition that needs medical guidance to evaluate.

Authoritative Resources

Verify any trial registration directly on ClinicalTrials.gov. For background on the FDA approval pathway that Phase 3 trials feed into, see the FDA drug approval process. For cancer-specific trial guidance, the National Cancer Institute publishes patient-oriented overviews. For global trial registrations beyond the U.S., the WHO ICTRP aggregates registries from around the world.

Frequently Asked Questions

How many clinical trials does Icahn School of Medicine at Mount Sinai have on ClinicalTrials.gov?

Icahn School of Medicine at Mount Sinai has 21 clinical trials registered on the federal ClinicalTrials.gov registry, of which 21 are actively recruiting participants right now. These counts come directly from the ClinicalTrials.gov API and are updated as the registry changes.

What conditions does Icahn School of Medicine at Mount Sinai study?

Icahn School of Medicine at Mount Sinai's registered trials cover 20 conditions on ClinicalTrials.gov, led by Bulimia Nervosa (3 trials), Multiple Sclerosis (2 trials), Traumatic Brain Injury (2 trials), ADHD (2 trials), Attention Deficit Hyperactivity Disorder (2 trials). The complete condition list appears in the sidebar of this page; each condition links to a page listing every recruiting trial in that area, regardless of sponsor.

How do I join a Icahn School of Medicine at Mount Sinai clinical trial?

Joining a clinical trial is a medical decision that should always involve your treating physician. Each trial page on this site includes the eligibility criteria translated into plain English alongside the official clinical text, plus the contact information that the sponsor has registered with ClinicalTrials.gov. Bring the trial information to your doctor before reaching out — they can review the full inclusion and exclusion criteria against your medical history and help you decide whether to pursue screening.

What does the trial phase mean?

Phase 1 trials test safety and dosing in small groups (often 20–80 healthy volunteers or patients). Phase 2 trials evaluate efficacy and side effects in larger groups (100–300 patients with the target condition). Phase 3 trials confirm efficacy and monitor safety in the largest groups (300–3,000+ patients) and form the basis of an FDA approval submission. Phase 4 studies happen after a treatment is approved, monitoring long-term safety and effectiveness in real-world use. Some trials register without a phase — common for device, behavioral, or observational studies.

Where does this trial data come from?

All trial data is pulled directly from the ClinicalTrials.gov API v2, the official federal trial registry maintained by the National Library of Medicine at NIH. Under FDAAA 801, most U.S. drug and device trials are required to register, making ClinicalTrials.gov the most comprehensive source. Sponsors are responsible for keeping their listings current; trial status can shift between data refreshes.

How This Sponsor Page Is Built

Every count on this page is derived directly from ClinicalTrials.gov API v2 records. Trial counts include all trials currently registered to this sponsor; the recruiting count reflects trials with status "Recruiting" or equivalent. Plain-English eligibility translations on each linked trial page preserve the original clinical text alongside an accessible version. Read the full methodology for the data pipeline and limitations.

Source: ClinicalTrials.gov API v2, maintained by the National Library of Medicine at NIH. Public domain. Cite as: "TrialFinderData. Data: ClinicalTrials.gov."

Medical disclaimer: This page is informational, not medical advice. Talk to your doctor about whether a clinical trial is right for you.

Last updated 2026-06-26 · 21 trials tracked for Icahn School of Medicine at Mount Sinai.