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TrialFinderData is for informational purposes only and does not provide medical advice. Always talk to your doctor.

Updated May 2026 · ClinicalTrials.gov

Medical University of South Carolina

17 clinical trials · 17 recruiting · OTHER

Medical University of South Carolina has 17 clinical trials registered on ClinicalTrials.gov, with 17 actively recruiting participants. The trials listed below cover 20 conditions across the phases listed in the sidebar. Always discuss any specific trial with your physician before contacting a study site.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About Medical University of South Carolina\'s Trial Portfolio

Medical University of South Carolina is a non-industry sponsor (academic medical center, hospital, foundation, or research network). Non-industry sponsors often investigate novel approaches, rare conditions, and behavioral or surgical interventions that commercial sponsors may not prioritize.

17 of Medical University of South Carolina's 17 registered trials are currently recruiting — roughly 100% of the portfolio. A high recruiting share usually points to an active research pipeline with multiple programs at the enrollment stage.

Medical University of South Carolina's research footprint spans Parkinson Disease (2 trials), Critical Illness Recovery (2), and Behavioral Health Concerns (2) as the top three conditions. The full condition list, sorted by trial count, is in the sidebar.

Not Applicable is the largest single phase in Medical University of South Carolina's portfolio at 65% of registered trials. The full phase breakdown appears in the sidebar.

Trials by Medical University of South Carolina

RECRUITINGPhase 2NCT06971744

Autophagy Maintenance (AUTOMAIN)

This is a single-institution, single-arm study with a safety lead-in to determine if previously established safe doses of autophagy drugs, hydroxychloroquine (HCQ) and nelfinavir...

Sponsor: Medical University of South CarolinaEnrolling: 381 location
Ovarian Cancer
RECRUITINGPhase 2NCT07227610

Brain Metastases in Greater Size - Hypofractionated Options Trial (BIGSHOT)

This is a randomized, phase II trial comparing staged stereotactic radiosurgery (SSRS) versus fractionated stereotactic radiotherapy (FSRT) in patients with large brain metastases...

Sponsor: Medical University of South CarolinaEnrolling: 541 location
Brain MetastasesCancer (With CNS Involvement)
RECRUITINGNCT05811936

The SNAP Tool for Head and Neck Cancer Survivor-Caregiver Dyads

In this randomized behavioral intervention, head and neck cancer (HNC) survivors and their caregivers (N=176 HNC survivor-caregiver dyads) will be randomized to either...

Sponsor: Medical University of South CarolinaEnrolling: 3521 location
Head and Neck CancerSurvivorshipCaregiver Burden+1
RECRUITINGNCT07399496

Accelerated TMS for Apathy in PD

This single-site, open-label pilot study will evaluate the feasibility, tolerability, and preliminary efficacy of accelerated intermittent theta-burst stimulation (iTBS) targeting...

Sponsor: Medical University of South CarolinaEnrolling: 151 location
Parkinson Disease
RECRUITINGPhase 4NCT06951906

Imaging Biomarkers of FOG Response to DBS

For this study, the investigators are recruiting 54 individuals with Parkinson's Disease and Freezing of Gait (FOG) who are planning to undergo Deep Brain Stimulation (DBS). The...

Sponsor: Medical University of South CarolinaEnrolling: 541 location
Freezing of Gait Symptoms in Parkinson's DiseaseDeep Brain Stimulation
RECRUITINGNCT06994728

Correlation of STN-DBS Induced Visuospatial Changes and Freezing of Gait

The purpose of this research is to determine how deep brain stimulation (DBS) for Parkinson's disease affects attention and visuospatial function. Additionally, this study will...

Sponsor: Medical University of South CarolinaEnrolling: 121 location
Parkinson DiseaseGait Disorders, NeurologicVisuospatial/Perceptual Abilities
RECRUITINGPhase 2NCT06845319

NeoCARD: Anthracycline-Free Neoadjuvant Chemoimmunotherapy in Triple-Negative Breast Cancer Patients

This is a single-arm Phase II study to assess the efficacy of a 12-18 week neoadjuvant carboplatin, paclitaxel, and pembrolizumab (CPP) regimen in a response-adaptive manner for...

Sponsor: Medical University of South CarolinaEnrolling: 431 location
Triple Negative Breast Cancer
RECRUITINGNCT06451003

Intervention to Improve Utilization of Extended Venous Thromboembolism Prophylaxis After Cancer Surgery

While blood clots after major cancer surgery are common and harmful to patients, the medications to decrease blood clot risk are seldom used after patients leave the hospital...

Sponsor: Medical University of South CarolinaEnrolling: 301 location
Venous ThromboembolismPulmonary EmbolismDeep Vein Thrombosis+2
RECRUITINGNCT06332209

Randomized Trial of Tele Vs. Clinic TF-CBT in Puerto Rico

The current study will evaluate TF-CBT delivered via tele-health for youth presenting with trauma symptoms via a randomized controlled trial. Goals of the current study are to...

Sponsor: Medical University of South CarolinaEnrolling: 801 location
Post-Traumatic Stress Disorder
RECRUITINGNCT07390786

Behavioral Health Collaborative Care Model in Post-ICU Clinic Family Pilot

This pilot study evaluates the feasibility and acceptability of implementing a Behavioral Health Collaborative Care Model (BH CoCM) for family members of ICU survivors. The...

Sponsor: Medical University of South CarolinaEnrolling: 1501 location
Critical Illness RecoveryBehavioral Health ConcernsAnxiety+4
RECRUITINGNCT07372586

Behavioral Health Collaborative Care Model in an ICU Recovery Clinic

Survivors of critical illness are at high risk for mental health issues such as anxiety, depression, and PTSD. This single-site, randomized controlled trial at the Medical...

Sponsor: Medical University of South CarolinaEnrolling: 1501 location
PICSAnxietyDepression - Major Depressive Disorder+6
RECRUITINGPhase 2NCT05064319

Gabapentin for Restoring GABA/Glutamate Homeostasis in Co-occurring Bipolar and Cannabis Use Disorders

This research study evaluates the effects of an FDA-approved medication Gabapentin in individuals with Bipolar Disorder who smoke marijuana. Participants in the study will will be...

Sponsor: Medical University of South CarolinaEnrolling: 681 location
Bipolar DisorderCannabis UseSchizoaffective Disorder, Bipolar Type+5
RECRUITINGNCT04998916

MPFC Theta Burst Stimulation as a Treatment Tool for Alcohol Use Disorder: Effects on Drinking and Incentive Salience

The purpose of this study is to develop transcranial magnetic stimulation (TMS), specifically TMS at a frequency known as theta burst stimulation (TBS), to see how it affects the...

Sponsor: Medical University of South CarolinaEnrolling: 861 location
Alcohol Use DisorderAlcohol DrinkingSubstance Use+2
RECRUITINGNCT06239350

Young Adult Tobacco/Nicotine and Cannabis Co-use

The goal of this project is to better understand the relationship between tobacco/nicotine and cannabis using behavioral economics during a tobacco/nicotine quit attempt. All...

Sponsor: Medical University of South CarolinaEnrolling: 3501 location
Tobacco Use DisorderNicotine Dependence
RECRUITINGNCT07353034

Functional Social Support in COPD Self-Management

This observational study aims to examine how different types of functional social support (emotional/informational, tangible, affectionate, and positive social interaction)...

Sponsor: Medical University of South CarolinaEnrolling: 1111 location
Chronic Obstructive Pulmonary Disease (COPD)
RECRUITINGNCT06828835

The REPOSE (Reach for Equity in Pediatric Sleep Evaluation) Navigation Intervention

This research study aims to find out the effect of REPOSE, a patient navigation intervention, on the receipt of equitable care among children with a broad range of socioeconomic...

Sponsor: Medical University of South CarolinaEnrolling: 801 location
Sleep Apnea, Obstructive
RECRUITINGNCT06035939

SMYLS Multi-site Trial

The purpose of this study is to find out whether a web-based intervention using a mobile app is helpful for teens and young adults with sickle cell disease (SCD) in learning how...

Sponsor: Medical University of South CarolinaEnrolling: 2721 location
Sickle Cell Disease

How to Approach a Trial Listing

Each trial card above links to a dedicated page with the official ClinicalTrials.gov data plus a plain-English translation of the eligibility criteria. We translate technical terminology (ECOG performance status, hepatic function values, exclusionary lab thresholds) into language that a patient or caregiver can understand, but the original clinical text and the live ClinicalTrials.gov record always govern any actual eligibility decision.

Before contacting a trial site, write down questions for your treating physician using the framework on our 25 Questions guide. Discuss whether the trial fits your treatment plan, what the time commitment looks like, and whether your insurance will cover the standard-of-care portions. Trials are not a substitute for a treatment plan — they are an addition that needs medical guidance to evaluate.

Authoritative Resources

Verify any trial registration directly on ClinicalTrials.gov. For background on the FDA approval pathway that Phase 3 trials feed into, see the FDA drug approval process. For cancer-specific trial guidance, the National Cancer Institute publishes patient-oriented overviews. For global trial registrations beyond the U.S., the WHO ICTRP aggregates registries from around the world.

Frequently Asked Questions

How many clinical trials does Medical University of South Carolina have on ClinicalTrials.gov?

Medical University of South Carolina has 17 clinical trials registered on the federal ClinicalTrials.gov registry, of which 17 are actively recruiting participants right now. These counts come directly from the ClinicalTrials.gov API and are updated as the registry changes.

What conditions does Medical University of South Carolina study?

Medical University of South Carolina's registered trials cover 20 conditions on ClinicalTrials.gov, led by Parkinson Disease (2 trials), Critical Illness Recovery (2 trials), Behavioral Health Concerns (2 trials), Anxiety (2 trials), Depression - Major Depressive Disorder (2 trials). The complete condition list appears in the sidebar of this page; each condition links to a page listing every recruiting trial in that area, regardless of sponsor.

How do I join a Medical University of South Carolina clinical trial?

Joining a clinical trial is a medical decision that should always involve your treating physician. Each trial page on this site includes the eligibility criteria translated into plain English alongside the official clinical text, plus the contact information that the sponsor has registered with ClinicalTrials.gov. Bring the trial information to your doctor before reaching out — they can review the full inclusion and exclusion criteria against your medical history and help you decide whether to pursue screening.

What does the trial phase mean?

Phase 1 trials test safety and dosing in small groups (often 20–80 healthy volunteers or patients). Phase 2 trials evaluate efficacy and side effects in larger groups (100–300 patients with the target condition). Phase 3 trials confirm efficacy and monitor safety in the largest groups (300–3,000+ patients) and form the basis of an FDA approval submission. Phase 4 studies happen after a treatment is approved, monitoring long-term safety and effectiveness in real-world use. Some trials register without a phase — common for device, behavioral, or observational studies.

Where does this trial data come from?

All trial data is pulled directly from the ClinicalTrials.gov API v2, the official federal trial registry maintained by the National Library of Medicine at NIH. Under FDAAA 801, most U.S. drug and device trials are required to register, making ClinicalTrials.gov the most comprehensive source. Sponsors are responsible for keeping their listings current; trial status can shift between data refreshes.

How This Sponsor Page Is Built

Every count on this page is derived directly from ClinicalTrials.gov API v2 records. Trial counts include all trials currently registered to this sponsor; the recruiting count reflects trials with status "Recruiting" or equivalent. Plain-English eligibility translations on each linked trial page preserve the original clinical text alongside an accessible version. Read the full methodology for the data pipeline and limitations.

Source: ClinicalTrials.gov API v2, maintained by the National Library of Medicine at NIH. Public domain. Cite as: "TrialFinderData. Data: ClinicalTrials.gov."

Medical disclaimer: This page is informational, not medical advice. Talk to your doctor about whether a clinical trial is right for you.

Last updated 2026-05-08 · 17 trials tracked for Medical University of South Carolina.

this entity is one of the data points covered by this site’s U.S. clinical trials and research registries dataset. The detail above comes directly from the NIH ClinicalTrials.gov registry; the context that follows situates the headline numbers against the broader distribution across active and historical clinical trials.

Every number on this page links back to the NIH ClinicalTrials.gov registry; the methodology page describes the inputs, refresh cadence, and known limitations of the underlying data product.

For readers using this page as a decision input, the related-entity pages elsewhere on the site provide the comparison set. The most useful comparison for this entity is typically a peer within active and historical clinical trials with similar size, similar exposure, or similar geography — not the national-level summary alone.