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Second Affiliated Hospital, School of Medicine, Zhejiang University

35 clinical trials · 35 recruiting · OTHER

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

Trials by Second Affiliated Hospital, School of Medicine, Zhejiang University

RECRUITINGNCT04960839

Prophylactic Irradiation to the Contralateral Breast for BCAs Patients

Breast cancer is the most common cancer in women worldwide, with high mortality. About 5% to 10% of breast cancers are hereditary. Most inherited cases of breast cancer are...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 3238 locations
Breast Cancer
RECRUITINGNCT07252986

Clinical Translation Research on a Multi-omics Breast Cancer Distant Metastasis Prediction Model Empowered by...

Breast cancer is one of the most common malignancies in women worldwide, and distant metastasis is the main cause of poor prognosis and death. This project aims to construct a...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 20001 location
BreastBreast CancerPathology
RECRUITINGPhase 2NCT06749691

Liposomal Irinotecan and Apatinib in ES-SCLC

The purpose of this study is to observe the efficacy and safety of liposomal irinotecan combined with apatinib in the treatment of extensive stage small cell lung cancer...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 301 location
Small Cell Lung Cancer Extensive Stage
RECRUITINGNCT06822413

Raman Spectroscopy-Based Deep Learning Model for Early Pan-Cancer Early Diagnosis

The goal of this observational study is to explore whether a Raman-based, deep learning-assisted approach can be used to develop an effective method for early pan-cancer...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 6004 locations
Cancer DiagnosisLiver Cancer, AdultCancer Screening+14
RECRUITINGNCT07198256

AI-assisted Diagnosis of Malignant Brain Tumors

This study aims to establish a large-scale, multi-center MRI database for malignant brain tumors. It will develop an artificial intelligence system for the segmentation and...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 30002 locations
GliomasBrain Metastases, AdultLymphoma+1
RECRUITINGNCT06760221

Safety and Efficacy of Preoperative SBRT and Radical Surgery for Soft Tissue Sarcoma of Extremities

Currently, the effectiveness and safety of preoperative hypo-fractionated radiotherapy in treating extremity soft tissue sarcomas remain inconclusive, warranting further...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 201 location
Soft Tissue SarcomaStereotactic Body RadiotherapySurgery
RECRUITINGNCT04939922

China Headache and Vertigo Registry Study

In the Chinese Headache and Vertigo Registration Study, patients aged 4-99 years with headache (primary headache and secondary headache such as migraine and tension type...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 100001 location
Headache Disorders, PrimaryHeadache Disorders, SecondaryMigraine+5
RECRUITINGNCT03502408

Perfusion Imaging Evaluation for Ischemic Stroke on 6-24 Hours Undergoing Endovascular Thrombectomy

This study aims to evaluate the hypothesis that thrombectomy devices plus medical management leads to superior clinical outcomes in acute ischemic stroke patients at 90 days as...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 551 location
Stroke, Acute Cerebral Infarction
RECRUITINGNCT05923931

Non-inferiority Study of the Effect of Non-cooling Blanket on Body Temperature in Patients With Heat Stroke

The goal of this clinical trial is to test the cooling effect of cooling blanket in patients with heat stroke. The main questions it aims to answer are: * the cooling rate of...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 1007 locations
Heat Stroke
RECRUITINGPhase 4NCT04937699

Sequential MonotherApy of TicagrElor and Clopidogrel After Coronary Intervention

The MATE study is a randomized, multicenter, open-label, investigator-initiated clinical trial aimed to evaluate efficacy and safety of sequential monotherapy of ticagrelor and...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 26901 location
Acute Coronary SyndromePercutaneous Coronary Intervention
RECRUITINGNCT06630936

Study of Atrial Fibrillation Combined with Atrial Functional Mitral Regurgitation

To evaluate the improvement of mitral regurgitation after catheter ablation of atrial fibrillation or regular drug therapy in atrial fibrillation patients combined with atrial...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 5001 location
Atrial Fibrillation (AF)Atrial Functional Mitral Regurgitation
RECRUITINGNCT06968962

Comparison of Sequential to Initial Combination Therapy in PAH

This is a multicenter, randomized, controlled, double-blind, and non-inferiority clinical trial to compare the efficacy of sequential to initial combination therapy in patients...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 3761 location
Pulmonary Arterial Hypertension (PAH)
RECRUITINGPhase 4NCT05718128

Clinical Study of Endocardial Myocardial Biopsy

In this study, patients with endocardial myocardial biopsy were selected to observe the safety of the operation, and pathological examination was performed. If necessary, special...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 1001 location
MyocarditisCardiomyopathiesHeart Failure+2
RECRUITINGNCT04454177

SMART Watch Facilitated Early Discharge in Patients Undergoing Transcatheter Aortic Valve Replacement

The purpose of this study is to observe conduction disturbance, daily activity level, heart rates, oxygen saturation in patients who underwent Transcatheter Aortic Valve...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 1001 location
Aortic StenosisValvular Heart DiseaseTranscatheter Aortic Valve Replacement
RECRUITINGNCT07267117

Cohort Observing Mechanisms, Progression and Sequelae of Valvular Heart Disease

The objective of this study is to evaluate and predict the progression of moderate cardiac valve stenosis and regurgitation using clinical, biological, echocardiographic, computed...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 1000015 locations
Heart Valve DiseaseMitral Valve (MV) RegurgitationMitral Valve Disease+11
RECRUITINGNCT06742125

Drug-Coated Balloon Versus Drug-Eluting Stent in Patient With ST-Segment Elevation Myocardial Infarction

Acute ST-segment elevation myocardial infarction (STEMI) is a life-threatening emergency requiring immediate intervention. The incidence of premature coronary artery disease...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 12441 location
ST-elevation Myocardial Infarction (STEMI)
RECRUITINGPhase 3NCT04067505

Rivaroxaban for the Prevention of Deep Vein Thrombosis in Patients With Left Iliac Vein Compression - The PLICTS Study

The purpose of this study is to evaluate the efficacy and safety of rivaroxaban for the prevention of deep vein thrombosis in patients with left iliac vein compression treated...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 2249 locations
May-Thurner Syndrome
RECRUITINGNCT07479758

Biomarker Research on Ultra-High-Field MRI Combined With Visual Perception Assessment in the Diagnosis and Treatment...

This is an observational study aiming to screen biomarkers associated with the diagnosis and treatment outcomes of severe mental disorders (MDD/major depressive disorder,...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 3201 location
Major Depressive Disorder (MDD)SchizophreniaBipolar Disorder+1
RECRUITINGNCT07444060

Guselkumab Vs Ustekinumab in Stricturing Crohn's Disease

This study intends to select patients with confirmed moderate-to-severe Crohn's disease (CD) and obstructive symptoms of intestinal stenosis, who have clear evidence of lumen...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 1001 location
CD - Crohn's DiseaseStricture; BowelIBD - Inflammatory Bowel Disease
RECRUITINGNCT06939712

A Study on the Impact of Online Positive Psychological Intervention on the Mental Health and Quality of Life of Crohn's...

Crohn's disease (CD) is a chronic, nonspecific inflammatory disease that can affect the entire digestive tract. It is difficult to cure and often relapses, causing long-term...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 1201 location
Crohn Disease
RECRUITINGNCT05387031

Efficacy of Ustekinumab Therapy in Patients With Symptomatic Stricturing Crohn's Disease

This study intends to select patients with confirmed moderate-to-severe Crohn's disease (CD) and obstructive symptoms of intestinal stenosis, who have clear evidence of lumen...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 2398 locations
Crohn DiseaseStricture; BowelIntestinal Stricture
RECRUITINGPhase 4NCT06609447

The Efficacy and Safety of Combining Probiotic VSL#3 With Vedolizumab for the Treatment of Moderate Ulcerative Colitis

An imbalance in the gut microbiota and mucosal immune dysfunction leading to intestinal inflammation are central to the pathogenesis of ulcerative colitis (UC). Both international...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 10012 locations
Ulcerative Colitis
RECRUITINGPhase 2NCT06375005

Efficacy and Safety of Telitacicept in the Treatment of Systemic Sclerosis

This study is a prospective, open-label, randomized, controlled, multi-center clinical trial. The aim of this study is to investigate the efficacy and safety of Telitacicept in...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 389 locations
Diffuse Cutaneous Systemic Sclerosis
RECRUITINGNCT06863532

Efficacy and Safety Comparison of Cofrogliptin Add-on Versus Metformin Dose-escalation in Type 2 Diabetes Patients...

The aim of this study is to evaluate the change in glycated hemoglobin (HbA1c) levels of adding cofrogliptin compared to escalation of metformin dose after 24 weeks in type 2...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 801 location
Type 2 Diabetes
RECRUITINGNCT07293325

Semaglutide and Tirzepatide for Genetic Aging Delay in Adults With Obesity

This study is a prospective, randomized, open-label clinical trial enrolling 66 adults with simple obesity who have not used weight-loss medications for at least 3 months....

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 661 location
Adults With Simple Obesity
RECRUITINGNCT04966793

Microbial Colonization Distribution and Adaptive Evolution of Lower Respiratory Tract in Bronchiectasis Patients.

Qualified sputum samples from bronchiectasis patients were collected regularly every month for three consecutive years to analyze the microbiome changes of lower respiratory tract...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 18501 location
Bronchiectasis
RECRUITINGPhase 4NCT07114120

Clinical Study on the Treatment of Stable Bronchiectasis With Bailing Capsules Combined With Guben Kechuan Granules

The goal of this clinical trial is to learn if Bailing Capsules in combination Guben Kechuan Granules works to treat stable bronchiectasis in adults.It will also learn about the...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 2145 locations
BronchiectasisCOPD
RECRUITINGNCT06741553

Prospective Cohort Study of Patients With Early Alzheimer's Disease Treated With Lecanemab

As the population increases and aging intensifies, cognitive disorders represented by Alzheimer's disease (AD) not only pose a severe threat to public health but also bring...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 1201 location
Alzheimer DiseaseMild Cognitive Impairment (MCI)
RECRUITINGPhase 4NCT04935021

Clinical Study of ATTR-CM

In this study, patients with ATTR-CM or gene carriers were selected to study the diagnosis and treatment, and long-term follow-up was conducted.

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 1001 location
Transthyroxine Amyloidosis Cardiomyopathy
RECRUITINGNCT07354009

Efficacy and Safety of iStent in Reducing Intraocular Pressure in Open-angle Glaucoma

To evaluate the efficacy and safety of istent inject W in reducing intraocular pressure in Chinese adult patients with open-angle glaucoma complicated with cataract.

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 601 location
Glaucoma

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