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Updated June 2026 · ClinicalTrials.gov

Second Affiliated Hospital, School of Medicine, Zhejiang University

Reviewed by TrialFinderData Editorial Team · Updated

43 clinical trials · 43 recruiting · OTHER

Second Affiliated Hospital, School of Medicine, Zhejiang University has 43 clinical trials registered on ClinicalTrials.gov, with 43 actively recruiting participants. The trials listed below cover 20 conditions across the phases listed in the sidebar. Always discuss any specific trial with your physician before contacting a study site.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About Second Affiliated Hospital, School of Medicine, Zhejiang University\'s Trial Portfolio

Second Affiliated Hospital, School of Medicine, Zhejiang University is a non-industry sponsor (academic medical center, hospital, foundation, or research network). Non-industry sponsors often investigate novel approaches, rare conditions, and behavioral or surgical interventions that commercial sponsors may not prioritize.

43 of Second Affiliated Hospital, School of Medicine, Zhejiang University's 43 registered trials are currently recruiting — roughly 100% of the portfolio. A high recruiting share usually points to an active research pipeline with multiple programs at the enrollment stage.

Second Affiliated Hospital, School of Medicine, Zhejiang University's research footprint spans Cataract (3 trials), Brain Tumor Adult (2), and Soft Tissue Sarcoma (2) as the top three conditions. The full condition list, sorted by trial count, is in the sidebar.

is the largest single phase in Second Affiliated Hospital, School of Medicine, Zhejiang University's portfolio at 30% of registered trials. The full phase breakdown appears in the sidebar.

Trials by Second Affiliated Hospital, School of Medicine, Zhejiang University

RECRUITINGPhase 2NCT05914389

Induction Chemotherapy Combined With Neoadjuvant Immunotherapy for MSS Colon Cancer

This study aims to elucidate the regression effects of neoadjuvant chemotherapy combined with immunotherapy and adjuvant therapy in locally advanced MSS colon cancer.

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 1001 location
Colon Neoplasm
RECRUITINGPhase 1NCT06946615

Exploratory Clinical Study of Claudin18.2-Targeted CAR-DC and CAR-T Therapy in Advanced Colorectal Cancer

This is an open-label, single-arm clinical study designed to evaluate the safety and preliminary efficacy of Claudin18.2-targeted CAR-DC combined with CAR-T cell therapy in...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 181 location
Colorectal Neoplasia
RECRUITINGPhase 1NCT07247396

CEA CAR-T Therapy After Cytoreduction in Colorectal Cancer Patients With Peritoneal Metastases

This single-arm, open-label, dose-escalation trial aims to evaluate the safety and efficacy of CEA-targeted CAR-T cells and to obtain their pharmacokinetic profile in patients...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 121 location
Peritoneal Metastases From Colorectal Cancer
RECRUITINGPhase 2NCT07078500

Orelabrutinib Combined With Pola-R-CHP Regimen for the Treatment of Untreated Non-GCB Diffuse Large B-Cell Lymphoma

Assess the preliminary efficacy and safety of orelabrutinib in combination with the Pola-R-CHP regimen for the treatment of treatment-naive Non-GCB diffuse large B-cell lymphoma.

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 481 location
Diffuse Large B-Cell Lymphoma (DLBCL)
RECRUITINGPhase 2NCT07193654

Stupp Treatment With Intrathecal Injection of Thiotepa for Glioblastoma With Advanced Spread

The goal of this clinical trial is to learn if a combined treatment approach can treat glioblastoma (GBM) with ventricular invasion or meningeal metastasis in adults. The main...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 381 location
Glioblastoma (GBM)
RECRUITINGNCT07198256

AI-assisted Diagnosis of Malignant Brain Tumors

This study aims to establish a large-scale, multi-center MRI database for malignant brain tumors. It will develop an artificial intelligence system for the segmentation and...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 30002 locations
GliomasBrain Metastases, AdultLymphoma+1
RECRUITINGNCT07417800

Construction and Clinical Validation of a Predictive Model for Postoperative Adjuvant Therapy in Hepatocellular...

Hepatocellular carcinoma (HCC) is a high-mortality global malignancy with a heavy disease burden in China. Although curative surgical resection improves survival for early-stage...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 110001 location
Hepatocellular Carcinoma (HCC)Artificial IntelligentAdjuvant Chemoradiotherapy+3
RECRUITINGPhase 2NCT07243626

Efficacy and Safety of Envafolimab Plus Doxorubicin and Ifosfamide for Advanced Soft Tissue Sarcoma

Soft tissue sarcoma (STS) is a rare, highly heterogeneous malignancy with a poor prognosis. The standard first-line treatment for advanced patients is anthracyclines (doxorubicin,...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 251 location
Soft Tissue Sarcoma
RECRUITINGPhase 2NCT05926700

Efficacy and Safety of Cadonilimab Plus Anlotinib in Advanced STS That Failed the Previous First-line Standard Treatment

Objective to evaluate the efficacy and safety of candonilimab combined with anlotinib in the treatment of progressive or metastatic soft tissue sarcoma that failed previous...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 271 location
Soft Tissue Sarcoma
RECRUITINGNCT06741553

Prospective Cohort Study of Patients With Early Alzheimer's Disease Treated With Lecanemab

As the population increases and aging intensifies, cognitive disorders represented by Alzheimer's disease (AD) not only pose a severe threat to public health but also bring...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 1201 location
Alzheimer DiseaseMild Cognitive Impairment (MCI)
RECRUITINGNCT07460037

Chinese-Specific Speech Imagery Coding Using High-Density ECoG

The goal of this study is to investigate whether high-density electrocorticography (ECoG) signals recorded from the surface of the brain can be used to decode neural...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 501 location
AphasiaDysarthriaALS+5
RECRUITINGNCT05418218

International Headache Registry Study

In the International Headache and Vertigo Registration Study, patients aged 4-99 years with headache (primary headache and secondary headache such as migraine and tension type...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 2000001 location
Headache Disorders, PrimaryHeadache Disorders, SecondaryMigraine+4
RECRUITINGPhase 3NCT05484349

TIzanidine for the Preventive Treatment of Episodic MigrainE (TIME)

In this study,189 adult migraine patients aged 18-65 years (diagnosed with migraine without aura and/or migraine with aura, with at least a 1-year history)will be collected to...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 1896 locations
Migraine Without AuraMigraine With Aura
RECRUITINGPhase 3NCT04151472

Idebenone for the Preventive Treatment of Migraine

Idebenone improves energy metabolism similarly to Coenzyme Q10, which is effective in migraine prophylaxis. The investigators compare idebenone (90 mg/day, 270 mg/day) and placebo...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 1801 location
Migraine DisordersHeadache Disorders
RECRUITINGPhase 4NCT04624295

Early Antiplatelet Therapy After Hemorrhagic Infarction in Acute Ischemic Stroke Treated With Intravenous Thrombolysis...

Previous study showed that the proportions of hemorrhagic Infarction after intravenous thrombolysis were 24.2% and 32.5% in the control group and the alteplase group, and most of...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 2941 location
Antiplatelet TherapyHemorrhagic Infarction
RECRUITINGPhase 4NCT05718128

Clinical Study of Endocardial Myocardial Biopsy

In this study, patients with endocardial myocardial biopsy were selected to observe the safety of the operation, and pathological examination was performed. If necessary, special...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 1001 location
MyocarditisCardiomyopathiesHeart Failure+2
RECRUITINGNCT06630936

Study of Atrial Fibrillation Combined with Atrial Functional Mitral Regurgitation

To evaluate the improvement of mitral regurgitation after catheter ablation of atrial fibrillation or regular drug therapy in atrial fibrillation patients combined with atrial...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 5001 location
Atrial Fibrillation (AF)Atrial Functional Mitral Regurgitation
RECRUITINGNCT06968962

Comparison of Sequential to Initial Combination Therapy in PAH

This is a multicenter, randomized, controlled, double-blind, and non-inferiority clinical trial to compare the efficacy of sequential to initial combination therapy in patients...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 3761 location
Pulmonary Arterial Hypertension (PAH)
RECRUITINGNCT07617844

Multimodal mAgnetic Resonance imaGIng in Cardiovascular Disease

This single-center, prospective, observational cohort study aims to evaluate the clinical application value of multi-modal cardiovascular magnetic resonance (CMR) imaging in...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 20001 location
Cardiovascular DiseasesIschemic Heart Disease (IHD)Cardiomyopathy+2
RECRUITINGNCT04454177

SMART Watch Facilitated Early Discharge in Patients Undergoing Transcatheter Aortic Valve Replacement

The purpose of this study is to observe conduction disturbance, daily activity level, heart rates, oxygen saturation in patients who underwent Transcatheter Aortic Valve...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 1001 location
Aortic StenosisValvular Heart DiseaseTranscatheter Aortic Valve Replacement
RECRUITINGNCT06595992

Prospective Observational Cohort Study of Moderate Aortic Valve Disease

The objective of this research is to evaluate and predict the progression of moderate aortic stenosis and regurgitation from clinical characterization, biological,...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 10001 location
Moderate Aortic Valve StenosisModerate Aortic Valve RegurgitationAortic Valve Disease
RECRUITINGPhase 4NCT02803294

Transcatheter Aortic Valve Replacement Single Center Registry in Chinese Population

The purpose of this study is to evaluate the safety and effectiveness of transcatheter aortic valve replacement in Chinese population.

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 20001 location
Symptomatic Aortic Stenosis
RECRUITINGPhase 3NCT07381803

The Impact of Fexofenadine Hydrochloride on the Prognosis of Patients Post-Acute Myocardial Infarction

The goal of this study is o evaluate the prognostic effect of fexofenadine hydrochloride in patients with myocardial infarction

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 28041 location
Zhejiang University
RECRUITINGNCT06742125

Drug-Coated Balloon Versus Drug-Eluting Stent in Patient With ST-Segment Elevation Myocardial Infarction

Acute ST-segment elevation myocardial infarction (STEMI) is a life-threatening emergency requiring immediate intervention. The incidence of premature coronary artery disease...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 12441 location
ST-elevation Myocardial Infarction (STEMI)
RECRUITINGNCT06434766

Multicenter iTBS Neuromodulation for PTSD Treatment

The proposed study aims to evaluate the efficacy of intermittent theta-burst transcranial magnetic stimulation (iTBS) targeting primary motor cortex (M1) as adjunct treatment for...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 1405 locations
Posttraumatic Stress Disorder
RECRUITINGNCT07479758

Biomarker Research on Ultra-High-Field MRI Combined With Visual Perception Assessment in the Diagnosis and Treatment...

This is an observational study aiming to screen biomarkers associated with the diagnosis and treatment outcomes of severe mental disorders (MDD/major depressive disorder,...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 3201 location
Major Depressive Disorder (MDD)SchizophreniaBipolar Disorder+1
RECRUITINGNCT06939712

A Study on the Impact of Online Positive Psychological Intervention on the Mental Health and Quality of Life of Crohn's...

Crohn's disease (CD) is a chronic, nonspecific inflammatory disease that can affect the entire digestive tract. It is difficult to cure and often relapses, causing long-term...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 1201 location
Crohn Disease
RECRUITINGNCT07385131

Prophylactic Dexamethasone Before Infliximab in Moderate-to-Severe IBD

This comparative observational cohort clinical study aims to investigate the necessity of premedication for allergy prevention prior to infliximab injection, and is designed to...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 3001 location
Inflammatory Bowel Disease (IBD)CD - Crohn's DiseaseUC - Ulcerative Colitis
RECRUITINGNCT05503875

Immunoclassification of Psoriasis: a Strategy for Precision Medicine

Through the combination of clinical manifestations and omics, the investigators aim to explore the skin cell atlas in different stages of psoriasis lesions, establish a clinical...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 1001 location
ImmunoclassificationPsoriasis
RECRUITINGNCT07532486

A Study to Evaluate Comparative Efficacy and Safety of Guselkumab in High-dose and Extended-interval Versus...

The purpose of this study is to evaluate the efficacy, safety, tolerability and drug survival of guselkumab in high-dose and extended-interval versus standard-dose in Chinese...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 4001 location
Psoriasis

Showing 30 of 43 trials. The remainder are accessible through individual condition pages or directly on ClinicalTrials.gov.

How to Approach a Trial Listing

Each trial card above links to a dedicated page with the official ClinicalTrials.gov data plus a plain-English translation of the eligibility criteria. We translate technical terminology (ECOG performance status, hepatic function values, exclusionary lab thresholds) into language that a patient or caregiver can understand, but the original clinical text and the live ClinicalTrials.gov record always govern any actual eligibility decision.

Before contacting a trial site, write down questions for your treating physician using the framework on our 25 Questions guide. Discuss whether the trial fits your treatment plan, what the time commitment looks like, and whether your insurance will cover the standard-of-care portions. Trials are not a substitute for a treatment plan — they are an addition that needs medical guidance to evaluate.

Authoritative Resources

Verify any trial registration directly on ClinicalTrials.gov. For background on the FDA approval pathway that Phase 3 trials feed into, see the FDA drug approval process. For cancer-specific trial guidance, the National Cancer Institute publishes patient-oriented overviews. For global trial registrations beyond the U.S., the WHO ICTRP aggregates registries from around the world.

Frequently Asked Questions

How many clinical trials does Second Affiliated Hospital, School of Medicine, Zhejiang University have on ClinicalTrials.gov?

Second Affiliated Hospital, School of Medicine, Zhejiang University has 43 clinical trials registered on the federal ClinicalTrials.gov registry, of which 43 are actively recruiting participants right now. These counts come directly from the ClinicalTrials.gov API and are updated as the registry changes.

What conditions does Second Affiliated Hospital, School of Medicine, Zhejiang University study?

Second Affiliated Hospital, School of Medicine, Zhejiang University's registered trials cover 20 conditions on ClinicalTrials.gov, led by Cataract (3 trials), Brain Tumor Adult (2 trials), Soft Tissue Sarcoma (2 trials), Myocarditis (2 trials), Psoriasis (2 trials). The complete condition list appears in the sidebar of this page; each condition links to a page listing every recruiting trial in that area, regardless of sponsor.

How do I join a Second Affiliated Hospital, School of Medicine, Zhejiang University clinical trial?

Joining a clinical trial is a medical decision that should always involve your treating physician. Each trial page on this site includes the eligibility criteria translated into plain English alongside the official clinical text, plus the contact information that the sponsor has registered with ClinicalTrials.gov. Bring the trial information to your doctor before reaching out — they can review the full inclusion and exclusion criteria against your medical history and help you decide whether to pursue screening.

What does the trial phase mean?

Phase 1 trials test safety and dosing in small groups (often 20–80 healthy volunteers or patients). Phase 2 trials evaluate efficacy and side effects in larger groups (100–300 patients with the target condition). Phase 3 trials confirm efficacy and monitor safety in the largest groups (300–3,000+ patients) and form the basis of an FDA approval submission. Phase 4 studies happen after a treatment is approved, monitoring long-term safety and effectiveness in real-world use. Some trials register without a phase — common for device, behavioral, or observational studies.

Where does this trial data come from?

All trial data is pulled directly from the ClinicalTrials.gov API v2, the official federal trial registry maintained by the National Library of Medicine at NIH. Under FDAAA 801, most U.S. drug and device trials are required to register, making ClinicalTrials.gov the most comprehensive source. Sponsors are responsible for keeping their listings current; trial status can shift between data refreshes.

How This Sponsor Page Is Built

Every count on this page is derived directly from ClinicalTrials.gov API v2 records. Trial counts include all trials currently registered to this sponsor; the recruiting count reflects trials with status "Recruiting" or equivalent. Plain-English eligibility translations on each linked trial page preserve the original clinical text alongside an accessible version. Read the full methodology for the data pipeline and limitations.

Source: ClinicalTrials.gov API v2, maintained by the National Library of Medicine at NIH. Public domain. Cite as: "TrialFinderData. Data: ClinicalTrials.gov."

Medical disclaimer: This page is informational, not medical advice. Talk to your doctor about whether a clinical trial is right for you.

Last updated 2026-06-26 · 43 trials tracked for Second Affiliated Hospital, School of Medicine, Zhejiang University.