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TrialFinderData is for informational purposes only and does not provide medical advice. Always talk to your doctor.

Updated June 2026 · ClinicalTrials.gov

Sheba Medical Center

Reviewed by TrialFinderData Editorial Team · Updated

6 clinical trials · 6 recruiting · OTHER_GOV

Sheba Medical Center has 6 clinical trials registered on ClinicalTrials.gov, with 6 actively recruiting participants. The trials listed below cover 18 conditions across the phases listed in the sidebar. Always discuss any specific trial with your physician before contacting a study site.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About Sheba Medical Center\'s Trial Portfolio

Sheba Medical Center is a non-industry sponsor (academic medical center, hospital, foundation, or research network). Non-industry sponsors often investigate novel approaches, rare conditions, and behavioral or surgical interventions that commercial sponsors may not prioritize.

6 of Sheba Medical Center's 6 registered trials are currently recruiting — roughly 100% of the portfolio. A high recruiting share usually points to an active research pipeline with multiple programs at the enrollment stage.

Sheba Medical Center's research footprint spans Ovarian Neoplasms (1 trials), carcinoma-ovarian-epithelial (1), and neoplasm-of-stomach (1) as the top three conditions. The full condition list, sorted by trial count, is in the sidebar.

Phase 2 is the largest single phase in Sheba Medical Center's portfolio at 33% of registered trials. The full phase breakdown appears in the sidebar.

Trials by Sheba Medical Center

RECRUITINGPhase 2NCT04519151

Pembrolizumab and Lenvatinib for Platinum- Sensitive Recurrent Ovarian Cancer

This is a study of pembrolizumab (MK-3475, KEYTRUDA®) in combination with lenvatinib (E7080) for the treatment of platinum sensitive recurrent ovarian cancer. Participants will...

Sponsor: Sheba Medical CenterEnrolling: 241 location
Ovarian NeoplasmsCarcinoma, Ovarian EpithelialNeoplasm of Stomach+5
RECRUITINGPhase 2NCT05909618

Crizanlizumab Alone or in Combination With Nivolumab for Glioblastoma and Melanoma With Brain Metastases

A single-center, open-label, non-randomized phase I/II study to evaluate the efficacy, safety and tolerance of crizanlizumab monotherapy and in combination with nivolumab in...

Sponsor: Sheba Medical CenterEnrolling: 331 location
Advanced GlioblastomaMetastatic Melanoma in the Central Nervous SystemMGMT-Unmethylated Glioblastoma
RECRUITINGNCT07224451

Liquid Biopsy Following BBB Disruption Using Barrier Disrupting Fields in Patients Undergoing Spine Surgery

Objective: To identify new central nervous system (CNS) biomarkers to be used for blood-derived liquid biopsy once the blood-brain barrier (BBB), specifically the blood-arachnoid...

Sponsor: Sheba Medical CenterEnrolling: 201 location
Spinal Tumors
RECRUITINGNCT06037902

CPAP for Esophageal Cancer With Radiotherapy

The goal of this clinical trial is to test the use of CPAP in patients with esophgaeal cancer undergoing radiotherapy. The main questions it aims to answer are: * does use of...

Sponsor: Sheba Medical CenterEnrolling: 441 location
Esophageal Cancer
RECRUITINGNCT05908708

Closed-loop Medtronic 780G System in Youth With Type 1 Diabetes

The goal of this observational study is to describe data on Israeli children and youth using the 780G system including data regarding glycemic control parameters, various...

Sponsor: Sheba Medical CenterEnrolling: 1201 location
Type 1 DiabetesChild, Only
RECRUITINGNCT02014389

Evaluation of Objective Perimetry Using Chromatic Multifocal Pupillometer

Objective perimetry can better monitor visual field defects in retinal dystrophy and Glaucoma patients than conventional subjective perimetry. The PLR ( Pupil Light Reflex to...

Sponsor: Sheba Medical CenterEnrolling: 2001 location
Retinal DystrophiesRetinitis PigmentosaGlaucoma

How to Approach a Trial Listing

Each trial card above links to a dedicated page with the official ClinicalTrials.gov data plus a plain-English translation of the eligibility criteria. We translate technical terminology (ECOG performance status, hepatic function values, exclusionary lab thresholds) into language that a patient or caregiver can understand, but the original clinical text and the live ClinicalTrials.gov record always govern any actual eligibility decision.

Before contacting a trial site, write down questions for your treating physician using the framework on our 25 Questions guide. Discuss whether the trial fits your treatment plan, what the time commitment looks like, and whether your insurance will cover the standard-of-care portions. Trials are not a substitute for a treatment plan — they are an addition that needs medical guidance to evaluate.

Authoritative Resources

Verify any trial registration directly on ClinicalTrials.gov. For background on the FDA approval pathway that Phase 3 trials feed into, see the FDA drug approval process. For cancer-specific trial guidance, the National Cancer Institute publishes patient-oriented overviews. For global trial registrations beyond the U.S., the WHO ICTRP aggregates registries from around the world.

Frequently Asked Questions

How many clinical trials does Sheba Medical Center have on ClinicalTrials.gov?

Sheba Medical Center has 6 clinical trials registered on the federal ClinicalTrials.gov registry, of which 6 are actively recruiting participants right now. These counts come directly from the ClinicalTrials.gov API and are updated as the registry changes.

What conditions does Sheba Medical Center study?

Sheba Medical Center's registered trials cover 18 conditions on ClinicalTrials.gov, led by Ovarian Neoplasms (1 trial), carcinoma-ovarian-epithelial (1 trial), neoplasm-of-stomach (1 trial), ovarian-diseases (1 trial), genital-neoplasms-female (1 trial). The complete condition list appears in the sidebar of this page; each condition links to a page listing every recruiting trial in that area, regardless of sponsor.

How do I join a Sheba Medical Center clinical trial?

Joining a clinical trial is a medical decision that should always involve your treating physician. Each trial page on this site includes the eligibility criteria translated into plain English alongside the official clinical text, plus the contact information that the sponsor has registered with ClinicalTrials.gov. Bring the trial information to your doctor before reaching out — they can review the full inclusion and exclusion criteria against your medical history and help you decide whether to pursue screening.

What does the trial phase mean?

Phase 1 trials test safety and dosing in small groups (often 20–80 healthy volunteers or patients). Phase 2 trials evaluate efficacy and side effects in larger groups (100–300 patients with the target condition). Phase 3 trials confirm efficacy and monitor safety in the largest groups (300–3,000+ patients) and form the basis of an FDA approval submission. Phase 4 studies happen after a treatment is approved, monitoring long-term safety and effectiveness in real-world use. Some trials register without a phase — common for device, behavioral, or observational studies.

Where does this trial data come from?

All trial data is pulled directly from the ClinicalTrials.gov API v2, the official federal trial registry maintained by the National Library of Medicine at NIH. Under FDAAA 801, most U.S. drug and device trials are required to register, making ClinicalTrials.gov the most comprehensive source. Sponsors are responsible for keeping their listings current; trial status can shift between data refreshes.

How This Sponsor Page Is Built

Every count on this page is derived directly from ClinicalTrials.gov API v2 records. Trial counts include all trials currently registered to this sponsor; the recruiting count reflects trials with status "Recruiting" or equivalent. Plain-English eligibility translations on each linked trial page preserve the original clinical text alongside an accessible version. Read the full methodology for the data pipeline and limitations.

Source: ClinicalTrials.gov API v2, maintained by the National Library of Medicine at NIH. Public domain. Cite as: "TrialFinderData. Data: ClinicalTrials.gov."

Medical disclaimer: This page is informational, not medical advice. Talk to your doctor about whether a clinical trial is right for you.

Last updated 2026-06-26 · 6 trials tracked for Sheba Medical Center.