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Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

16 clinical trials · 16 recruiting · OTHER

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

Trials by Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

RECRUITINGPhase 1 / Phase 2NCT05981001

Study of Autologous Tumor-Draining Lymph Node-Derived Lymphocytes for Advanced HER2-Negative Breast Cancer

RATIONALE: Patients with HER2-negative advanced breast cancer have limited choice on targeted therapies, and often show only modest responses to available immunotherapies....

Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityEnrolling: 1701 location
Breast Neoplasms
RECRUITINGNCT06892093

Probiotics for Prevention of Neratinib-Induced Diarrhea in Breast Cancer Patients

This study aims to evaluate the efficacy and safety of probiotics for the prevention of diarrhea in patients with breast cancer receiving the tyrosine kinase inhibitor (TKI)...

Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityEnrolling: 3081 location
HER2-positive Breast CancerDiarrhea Caused by DrugNeratinib
RECRUITINGPhase 3NCT06278870

Disitamab Vedotin + Pyrotinib Versus THP in the First-line Treatment for HER2+ Advanced Breast Cancer Clinical Trial

The goal of this multicentre, randomized, double-blind controlled, phase III clinical trial is to compare the efficacy and safety of disitamab vedotin in combination with...

Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityEnrolling: 3121 location
HER2-positive Metastatic Breast CancerFirst-line Treatment
RECRUITINGPhase 2NCT06540729

RC48 in Combination With AK104 and Bevacizumab in OCCC

Disitamab vedotin (RC48) in combination with AK104 (PD-1/CTLA-4 bispecific) and bevacizumab for the treatment of recurrent and persistent clear cell ovarian cancer: a single-arm,...

Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityEnrolling: 391 location
Ovary Cancer
RECRUITINGPhase 2NCT05412589

mFOLFOX7 Plus Camrelizumab and Apatinib for Advanced HCC

This is a prospective, one-arm, phase II clinical study of intravenous mFOLFOX6 plus Camrelizumab combined with apatinib for CNLC stage III hepatocellular carcinoma

Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityEnrolling: 351 location
Stage III Hepatocellular Cancer (CNLC Staging)
RECRUITINGNCT06592755

Single-Incision Gasless Endoscopic Total Thyroidectomy Via Subclavian Approach Versus Open Surgery for PTC

Historically, performing a contralateral thyroid lobectomy and lymph node dissection via the subclavian approach was considered challenging. This study aimed to evaluate the...

Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityEnrolling: 1201 location
Papillary Thyroid Carcinoma
RECRUITINGNCT07488325

Multimodal Assessment of Malignancy in Atypia of Undetermined Significance in Thyroid Nodules Using Ultrasound and...

The prospective study aim to develop a multimodal deep learning model that integrates ultrasound images and cytological whole-slide images for more accurate malignant risk...

Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityEnrolling: 3961 location
Thyroid Nodule
RECRUITINGNCT06623578

Comparative Study of Transaxillary Robotic Thyroidectomy With MRND Versus Conventional Open Surgery in N1b PTC

Thyroid cancer is one of the most common malignant tumors in women, ranking seventh in the United States and fourth in China. Papillary thyroid carcinoma is the most common...

Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityEnrolling: 8761 location
Papillary Thyroid CarcinomaLymphatic Metastasis
RECRUITINGPhase 2NCT06365008

Sintilimab Plus FOLFIRI as Salvage Therapy for Patients With Advanced Gastric Cancer

The combination of immune checkpoint inhibitors and platinum containing dual drugs are more used as a first-line therapeutic approach for patients diagnosed with advanced gastric...

Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityEnrolling: 401 location
Unresectable/Metastatic Gastric Cancer
RECRUITINGNCT05892289

Feasibility and Safety of Robotic Assisted Proximal Gastrectomy With Double-flap Technique for Proximal Early Gastric...

Proximal early gastric cancer can choose radical total gastrectomy or proximal gastrectomy. The patients have poor nutritional status and quality of life after total gastrectomy....

Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityEnrolling: 421 location
Stomach Neoplasms
RECRUITINGNCT07401641

Effect of Dezocine Versus Nalbuphine Combined With Sufentanil on Postoperative Analgesia, Complications, and Free Flap...

Background: Oral cancer radical surgery often requires free flap reconstruction. Postoperative pain is severe, and traditional opioids like sufentanil have side effects and may...

Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityEnrolling: 601 location
Oral CancerPostoperative Pain ManagementFree Tissue Flaps+1
RECRUITINGNCT06221267

A Registry Study on Rimegepant for the Treatment of Migraine Participants in Guangdong-Hong Kong-Macao Greater Bay Area

This study is a single-arm, prospective, multicenter, observational registry study. It plans to enroll 120 migraine patients who meet the inclusion criteria and are treated with...

Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityEnrolling: 1201 location
Migraine
RECRUITINGPhase 2NCT06925516

A Trial of Apatinib and Adebrelimab in Combination With Chemotherapy in Patients With Unresectable ICC

The study aims to evaluate the efficacy and safety of Apatinib and Adebrelimab in Combination With chemotherapy in patients with advanced intrahepatic cholangiocarcinoma (ICC)

Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityEnrolling: 381 location
Intrahepatic Cholangiocarcinoma (Icc)
RECRUITINGNCT05937880

Leflunomide for Henoch-Schonlein Purpura

This study conducted a prospective, multicenter, one-arm clinical trial on the combination of leflunomide and steroid therapy for refractory skin Henoch-Schonlein Purpura in...

Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityEnrolling: 361 location
Henoch-Schonlein Purpura
RECRUITINGNCT06652113

Effect of HCQ Combined With LT4 on LBR in Euthyroid Women With URPL and TPO-Ab

The goal of this clinical trial is to learn if combined treatment of levothyroxine and hydroxychloroquine would improve the live birth of euthyroid women with thyroid peroxidase...

Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityEnrolling: 7962 locations
Recurrent Pregnancy LossEuthyroid With Thyroid Antibodies
RECRUITINGNCT06437652

An AI Algorithm for Lymphocyte Focus Score of Minor Salivary Gland Biopsy Samples for Diagnosing Sjogren's Syndrome

The aim of this research is to discover an artificial intelligence (AI) algorithm for lymphocyte focus score in whole slide images of labial minor salivary gland (SG) biopsy...

Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityEnrolling: 10001 location
Sjogren's Syndrome