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The Children's Hospital of Zhejiang University School of Medicine

6 clinical trials · 6 recruiting · OTHER

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

Trials by The Children's Hospital of Zhejiang University School of Medicine

RECRUITINGEarly Phase 1NCT07507201

Allogeneic CD19/BCMA CAR-T for B Cell-Related Autoimmune Disease

This is an exploratory, open-label, single-arm Phase 1 clinical study designed to evaluate the safety, tolerability, and preliminary efficacy of QT-219C. QT-219C is a universal...

Sponsor: The Children's Hospital of Zhejiang University School of MedicineEnrolling: 151 location
Autoimmune DiseasesSystemic Lupus Erthematosus (SLE)Multi-Drug Resistant Nephrotic Syndrome+3
RECRUITINGNCT07352332

Immune Profiling of Refractory cSLE Exposed to CD3×CD19 BiTE

This prospective observational study aims to characterize the peripheral immune landscape of pediatric patients with childhood-onset systemic lupus erythematosus ( cSLE) who are...

Sponsor: The Children's Hospital of Zhejiang University School of MedicineEnrolling: 61 location
Childhood-onset Systemic Lupus Erythematosus
RECRUITINGPhase 1NCT06792344

Clinical Study of CD19 CAR-T in the Treatment of Refractory Systemic Sclerosis

This is an investigator-initiated trial aimed at assessing the safety and efficacy of anti-CD19 CAR-T cells in the treatment of childhood-onset systemic sclerosis

Sponsor: The Children's Hospital of Zhejiang University School of MedicineEnrolling: 122 locations
Systemic Sclerosis (SSc)
RECRUITINGPhase 1NCT07305116

CAR T-cell Therapy Targeting CD19 and BCMA in Patients With B Cell Mediated Autoimmune Disease

CAR T-cell Therapy Targeting CD19 and BCMA in Patients With B cell mediated autoimmune disease.

Sponsor: The Children's Hospital of Zhejiang University School of MedicineEnrolling: 151 location
Autoimmune DiseasesSystemic Lupus Erthematosus (SLE)Multi-Drug Resistant Nephrotic Syndrome+3
RECRUITINGNCT06508346

Study of Therapeutic Efficacy of Anti-CD19 CAR-T Cells in Children With Refractory Refractory AAV

This is an investigator-initiated trial aimed at assessing the safety and efficacy of anti-CD19 CAR-T cells in the treatment of childhood-onset refractory ANCA-Associated...

Sponsor: The Children's Hospital of Zhejiang University School of MedicineEnrolling: 121 location
ANCA Associated VasculitisCAR-T Cell Therapy
RECRUITINGNCT06539624

Evaluate the Safety and Preliminary Efficacy of EXG110 in Subjects With Fabry Disease

Objective: To explore the safety and tolerability of different doses of EXG110 with Fabre disease

Sponsor: The Children's Hospital of Zhejiang University School of MedicineEnrolling: 122 locations
Fabry Disease