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TrialFinderData is for informational purposes only and does not provide medical advice. Always talk to your doctor.

Updated June 2026 · ClinicalTrials.gov

University Health Network, Toronto

Reviewed by TrialFinderData Editorial Team · Updated

26 clinical trials · 26 recruiting · OTHER

University Health Network, Toronto has 26 clinical trials registered on ClinicalTrials.gov, with 26 actively recruiting participants. The trials listed below cover 20 conditions across the phases listed in the sidebar. Always discuss any specific trial with your physician before contacting a study site.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About University Health Network, Toronto\'s Trial Portfolio

University Health Network, Toronto is a non-industry sponsor (academic medical center, hospital, foundation, or research network). Non-industry sponsors often investigate novel approaches, rare conditions, and behavioral or surgical interventions that commercial sponsors may not prioritize.

26 of University Health Network, Toronto's 26 registered trials are currently recruiting — roughly 100% of the portfolio. A high recruiting share usually points to an active research pipeline with multiple programs at the enrollment stage.

University Health Network, Toronto's research footprint spans Epilepsy (2 trials), hereditary-cancer-syndrome (1), and Prostate Cancer (1) as the top three conditions. The full condition list, sorted by trial count, is in the sidebar.

Not Applicable is the largest single phase in University Health Network, Toronto's portfolio at 62% of registered trials. The full phase breakdown appears in the sidebar.

Trials by University Health Network, Toronto

RECRUITINGNCT06726642

CfDNA in Hereditary And High-risk Malignancies 2

The goal of this study is to understand the performance of an experimental blood test that aims to detect early tumors in patients with hereditary cancer syndromes. If this new...

Sponsor: University Health Network, TorontoEnrolling: 10008 locations
Hereditary Cancer Syndrome
RECRUITINGNCT06877598

Canada-wide Implementation of a Virtual Sexual Health and Rehabilitation eClinic (SHAReClinic) for Prostate Cancer...

The goal of this observational study is to evaluate the effectiveness of SHAReClinic, a national, virtual Sexual Health and Rehabilitation eClinic designed to support prostate...

Sponsor: University Health Network, TorontoEnrolling: 57510 locations
Prostate CancerSexual Dysfunction, PhysiologicalSexual Dysfunction, Psychological+6
RECRUITINGPhase 2NCT06453486

A Study of High Dose Radiation Therapy for Locally Advanced Pancreatic Cancer That Responded to Initial Chemotherapy...

The goal of this clinical trial is to test the effect of high-dose radiation therapy after initial chemotherapy in patients with locally advanced pancreatic cancer. The main...

Sponsor: University Health Network, TorontoEnrolling: 432 locations
Locally Advanced Pancreatic Adenocarcinoma
RECRUITINGNCT06459271

Feasibility of CALM in Patients With Ovarian Cancer

The goal of this feasibility trial is to determine the feasibility and acceptability of implementing a brief evidence-based psychotherapeutic intervention, Managing Cancer And...

Sponsor: University Health Network, TorontoEnrolling: 501 location
Patient SatisfactionOvarian Cancer
RECRUITINGNCT05397873

Biofeedback for Hemianopia Vision Rehabilitation

Patients with brain injury secondary to stroke, surgery, or trauma frequently suffer from homonymous hemianopia, defined as vision loss in one hemifield secondary to retro-...

Sponsor: University Health Network, TorontoEnrolling: 321 location
Hemianopsia, HomonymousBrain InjuryStroke+2
RECRUITINGNCT07376837

Radiofrequency Ablation for Curative Treatment of Small Low-Risk Papillary Thyroid Cancer: Pilot Study

This pilot, single-arm clinical study evaluates the feasibility, safety, and effectiveness of radiofrequency ablation (RFA) as a curative treatment for small, low-risk papillary...

Sponsor: University Health Network, TorontoEnrolling: 301 location
Thyroid Papillary Carcinoma
RECRUITINGNCT04560036

FAZA PETMRI Gastro-Oesophageal Study

This is a single arm, pilot study of PET/MRI scan with radiotracer 18F-Fluoroazomycin Arabinoside (FAZA) before and after standard of care platinum-based chemotherapy for patients...

Sponsor: University Health Network, TorontoEnrolling: 401 location
Metastasized Gastro-Oesophageal Cancer
RECRUITINGNCT06085781

A Study of Head and Neck MRI and Tumor Microenvironment Biomarkers

The purpose of this study is to explore biomarker development in patients with newly diagnosed Head and neck squamous cell carcinoma (HNSCC) receiving curative therapy.

Sponsor: University Health Network, TorontoEnrolling: 601 location
Squamous Cell Carcinoma of Head and Neck
RECRUITINGNCT06871176

PET/MR Scan With [68Ga]Ga-PentixaFor (CXCR4) vs Standard of Care (SOC) for Initial Staging and Follow up in Multiple...

Multiple myeloma is a disease mainly located in participants bones. Usually a participants physician arrives at this diagnosis by doing blood tests and ordering standard of care...

Sponsor: University Health Network, TorontoEnrolling: 301 location
Multiple Myeloma
RECRUITINGPhase 2NCT07014137

A Trial of ABSK043, an Oral PD-L1 Inhibitor, in Patients With Angiogenic Sarcomas

ABSK043 is a new type of experimental drug that blocks a protein called programmed cell death ligand 1 (PD-L1), which is important in controlling the body's response to harmful...

Sponsor: University Health Network, TorontoEnrolling: 201 location
Sarcoma
RECRUITINGNCT06757569

Radialis PET Imager for the Assessment of Neuritic Amyloid Plaque Burden

The standard or usual workup for cognitive impairment, including Alzheimer's Disease, may include brain amyloid PET with PET/CT or PET/MR imaging. Amyloid PET is the standard...

Sponsor: University Health Network, TorontoEnrolling: 1601 location
Cognitive Impairment
RECRUITINGNCT07174973

Innovative Approaches to Enhance Balance and Neuroplasticity in Multiple Sclerosis

This study will evaluate the effects of combining balance training with electrical stimulation techniques in individuals with Multiple Sclerosis (MS). MS commonly impairs leg...

Sponsor: University Health Network, TorontoEnrolling: 241 location
Multiple SclerosisMobility LimitationBalance; Distorted+1
RECRUITINGNCT04526093

Real-World Evidence in Patient-Reported Outcomes for Medical Cannabis (MC-RWE)

This prospective observational study aims to describe the effectiveness of MC on pain, epilepsy, sleep and /or anxiety/depression in a cohorts of patients authorized to use MC,...

Sponsor: University Health Network, TorontoEnrolling: 10001 location
PainSleepAnxiety+2
RECRUITINGNCT05503290

The Lullaby Project as a Musical Intervention for Pregnant Individuals With Epilepsy

This study's proposed intervention is the randomized participation of pregnant individuals with epilepsy in the Lullaby Project coordinated by a musical institution in Toronto....

Sponsor: University Health Network, TorontoEnrolling: 301 location
EpilepsyPregnancy Related
RECRUITINGPhase 1NCT06506019

Neurobiological Effects of Psilocybin in Treatment Resistant Bipolar Depression

This study is an open-label, single-arm, proof-of-concept study, wherein treatment resistant bipolar depression (TRBD) participants will receive one 25 mg dose of oral psilocybin...

Sponsor: University Health Network, TorontoEnrolling: 301 location
Bipolar Depression
RECRUITINGNCT03675386

Reducing Opioid Use for Chronic Pain Patients Following Surgery

Patients with chronic pain are often prescribed long-term opioid therapy, despite the serious risks and growing concerns related to opioid use. The Toronto General Hospital has...

Sponsor: University Health Network, TorontoEnrolling: 2101 location
Chronic PainOpioid UsePostoperative Pain+1
RECRUITINGNCT07636382

Simulation-Free Celiac Plexus Pain Ablation Using Stereotactic Body Radiotherapy in Patients With Cancer-Related Celiac...

This is a prospective, single-arm, pilot feasibility clinical trial designed to evaluate the feasibility and safety of a simulation-free adaptive radiotherapy workflow to enable...

Sponsor: University Health Network, TorontoEnrolling: 51 location
Advanced CancerPancreatic Cancer
RECRUITINGPhase 3NCT06587867

Seronegative Myasthenia Gravis - Efgartigimod IV

This is to study the efficacy, safety and tolerability of efgartigimod in patients with seronegative generalized myasthenia gravis. This is an open label study. There will be 30...

Sponsor: University Health Network, TorontoEnrolling: 301 location
EfgartigimodGeneralized Myasthenia Gravis
RECRUITINGNCT02298439

Fatty Liver Patient Registry

The purpose of the Non-Alcoholic Fatty Liver Disease (NAFLD) registry is to collect demographic and clinical data on patients being treated for NAFLD and to determine the factors...

Sponsor: University Health Network, TorontoEnrolling: 1001 location
Non-Alcoholic Fatty Liver Disease
RECRUITINGNCT04007380

Psychosocial, Cognitive, and Behavioral Consequences of Sleep-disordered Breathing After SCI

This clinical trial will examine the efficacy of continuous positive airway pressure (CPAP) therapy in improving psychosocial, neurocognitive and behavioral consequences of...

Sponsor: University Health Network, TorontoEnrolling: 241 location
Spinal Cord InjuriesSleep Apnea
RECRUITINGNCT06220526

Comparing Menghini-type Needle and Franseen-type Needle in EBUS-TBNA for Sarcoidosis

This randomized pilot clinical trial aims to examine whether sample collection with Franseen-type needles are effective for the diagnosis of sarcoidosis, as defined by improved...

Sponsor: University Health Network, TorontoEnrolling: 1281 location
Suspected Sarcoidosis
RECRUITINGNCT06370832

Inspiratory Muscle Training in Lung Transplant Candidates

Recovery after lung transplantation (LTx) may be complicated by prolonged mechanical ventilation (MV) and protracted intensive care unit (ICU) stay leading to immobilization and...

Sponsor: University Health Network, TorontoEnrolling: 904 locations
Inspiratory Muscle Training
RECRUITINGPhase 4NCT07189377

Combined Light, ExVivo, and Antivirals for Recipients of Lungs From HBV Donors

The aim of the study is to show that transplantation of lungs from Hepatitis B-infected donors is safe when using EVLP with UV light inactivation plus antivirals

Sponsor: University Health Network, TorontoEnrolling: 201 location
Hepatitis B Virus (HBV)Lung Transplant Recipient
RECRUITINGPhase 3NCT07240558

Pandemic Influenza Vaccine in Organ Transplantation (PIVOT Trial)

Influenza is an important pathogen in transplant recipients. The current widespread outbreak of highly pathogenic H5N1 avian influenza (HPAI) in livestock, and the occurrence of...

Sponsor: University Health Network, TorontoEnrolling: 1201 location
Influenza (Pandemic)Avian InfluenzaVaccination
RECRUITINGNCT04856059

Fabry Cardiomyopathy: Identification of Early Myocardial Structural and Tissue Abnormalities Using Multiparametric MRI

This study will evaluate whether cardiac MRI T1 and T2 mapping improves our ability to detect early abnormalities in the heart in patients with Fabry disease and identify patients...

Sponsor: University Health Network, TorontoEnrolling: 3001 location
Fabry Disease
RECRUITINGNCT07409077

Efficacy of Biofeedback Training for Glaucoma

This randomized controlled clinical trial evaluates the efficacy of visual biofeedback training on visual function and quality of life in individuals with glaucoma. Glaucoma is a...

Sponsor: University Health Network, TorontoEnrolling: 701 location
GlaucomaBiofeedback Training

How to Approach a Trial Listing

Each trial card above links to a dedicated page with the official ClinicalTrials.gov data plus a plain-English translation of the eligibility criteria. We translate technical terminology (ECOG performance status, hepatic function values, exclusionary lab thresholds) into language that a patient or caregiver can understand, but the original clinical text and the live ClinicalTrials.gov record always govern any actual eligibility decision.

Before contacting a trial site, write down questions for your treating physician using the framework on our 25 Questions guide. Discuss whether the trial fits your treatment plan, what the time commitment looks like, and whether your insurance will cover the standard-of-care portions. Trials are not a substitute for a treatment plan — they are an addition that needs medical guidance to evaluate.

Authoritative Resources

Verify any trial registration directly on ClinicalTrials.gov. For background on the FDA approval pathway that Phase 3 trials feed into, see the FDA drug approval process. For cancer-specific trial guidance, the National Cancer Institute publishes patient-oriented overviews. For global trial registrations beyond the U.S., the WHO ICTRP aggregates registries from around the world.

Frequently Asked Questions

How many clinical trials does University Health Network, Toronto have on ClinicalTrials.gov?

University Health Network, Toronto has 26 clinical trials registered on the federal ClinicalTrials.gov registry, of which 26 are actively recruiting participants right now. These counts come directly from the ClinicalTrials.gov API and are updated as the registry changes.

What conditions does University Health Network, Toronto study?

University Health Network, Toronto's registered trials cover 20 conditions on ClinicalTrials.gov, led by Epilepsy (2 trials), hereditary-cancer-syndrome (1 trial), Prostate Cancer (1 trial), sexual-dysfunction-physiological (1 trial), sexual-dysfunction-psychological (1 trial). The complete condition list appears in the sidebar of this page; each condition links to a page listing every recruiting trial in that area, regardless of sponsor.

How do I join a University Health Network, Toronto clinical trial?

Joining a clinical trial is a medical decision that should always involve your treating physician. Each trial page on this site includes the eligibility criteria translated into plain English alongside the official clinical text, plus the contact information that the sponsor has registered with ClinicalTrials.gov. Bring the trial information to your doctor before reaching out — they can review the full inclusion and exclusion criteria against your medical history and help you decide whether to pursue screening.

What does the trial phase mean?

Phase 1 trials test safety and dosing in small groups (often 20–80 healthy volunteers or patients). Phase 2 trials evaluate efficacy and side effects in larger groups (100–300 patients with the target condition). Phase 3 trials confirm efficacy and monitor safety in the largest groups (300–3,000+ patients) and form the basis of an FDA approval submission. Phase 4 studies happen after a treatment is approved, monitoring long-term safety and effectiveness in real-world use. Some trials register without a phase — common for device, behavioral, or observational studies.

Where does this trial data come from?

All trial data is pulled directly from the ClinicalTrials.gov API v2, the official federal trial registry maintained by the National Library of Medicine at NIH. Under FDAAA 801, most U.S. drug and device trials are required to register, making ClinicalTrials.gov the most comprehensive source. Sponsors are responsible for keeping their listings current; trial status can shift between data refreshes.

How This Sponsor Page Is Built

Every count on this page is derived directly from ClinicalTrials.gov API v2 records. Trial counts include all trials currently registered to this sponsor; the recruiting count reflects trials with status "Recruiting" or equivalent. Plain-English eligibility translations on each linked trial page preserve the original clinical text alongside an accessible version. Read the full methodology for the data pipeline and limitations.

Source: ClinicalTrials.gov API v2, maintained by the National Library of Medicine at NIH. Public domain. Cite as: "TrialFinderData. Data: ClinicalTrials.gov."

Medical disclaimer: This page is informational, not medical advice. Talk to your doctor about whether a clinical trial is right for you.

Last updated 2026-06-26 · 26 trials tracked for University Health Network, Toronto.