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TrialFinderData is for informational purposes only and does not provide medical advice. Always talk to your doctor.

Updated June 2026 · ClinicalTrials.gov

University of California, San Francisco

Reviewed by TrialFinderData Editorial Team · Updated

38 clinical trials · 38 recruiting · OTHER

University of California, San Francisco has 38 clinical trials registered on ClinicalTrials.gov, with 38 actively recruiting participants. The trials listed below cover 20 conditions across the phases listed in the sidebar. Always discuss any specific trial with your physician before contacting a study site.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About University of California, San Francisco\'s Trial Portfolio

University of California, San Francisco is a non-industry sponsor (academic medical center, hospital, foundation, or research network). Non-industry sponsors often investigate novel approaches, rare conditions, and behavioral or surgical interventions that commercial sponsors may not prioritize.

38 of University of California, San Francisco's 38 registered trials are currently recruiting — roughly 100% of the portfolio. A high recruiting share usually points to an active research pipeline with multiple programs at the enrollment stage.

University of California, San Francisco's research footprint spans Glaucoma (3 trials), Tuberculosis (2), and Pompe Disease Infantile-Onset (2) as the top three conditions. The full condition list, sorted by trial count, is in the sidebar.

Not Applicable is the largest single phase in University of California, San Francisco's portfolio at 45% of registered trials. The full phase breakdown appears in the sidebar.

Trials by University of California, San Francisco

RECRUITINGNCT07546331

Novel Body Composition Measurements in Association With Outcomes of Breast Reconstruction Reconstruction

This study compares measurements of body composition to outcomes of breast reconstruction.

Sponsor: University of California, San FranciscoEnrolling: 401 location
Breast CarcinomaBreast Cancer
RECRUITINGNCT04291651

UCSF PANC Cyst Registry

Pancreatic cysts are found incidentally on 15-50% of CT and MRIs for all indications and their prevalence is increasing. Many of these cysts may be precursors to pancreatic...

Sponsor: University of California, San FranciscoEnrolling: 40001 location
Pancreatic CystPancreatic NeoplasmsPancreatic Cancer+5
RECRUITINGPhase 1 / Phase 2NCT06470282

Enfortumab Vedotin and Pembrolizumab Combined With Radiotherapy in Muscle Invasive Bladder Cancer

This phase Ib/II trial studies the side effects, best dose, and effectiveness of enfortumab vedotin (EV) in combination with pembrolizumab and radiation therapy for treating...

Sponsor: University of California, San FranciscoEnrolling: 471 location
Bladder CancerMuscle-Invasive Bladder CarcinomaStage II Bladder Cancer AJCC v8+1
RECRUITINGNCT07398157

Simplified, Scalable, 24-hour Adaptive DBS in Parkinson's Disease

The purpose of this study is to test a new way to treat Parkinson's disease (PD). Subjects will be implanted with deep brain stimulator (DBS) devices and electrodes placed under...

Sponsor: University of California, San FranciscoEnrolling: 241 location
PD - Parkinson's Disease
RECRUITINGNCT06085144

Emgality for Migraine in Breastmilk

The goal of this project is to evaluate galcanezumab transfer into maternal breastmilk, and to evaluate infant (growth, development, constipation, colic, infections) and maternal...

Sponsor: University of California, San FranciscoEnrolling: 301 location
Migraine
RECRUITINGNCT04144972

Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain

Chronic pain affects 1 in 4 US adults, and many cases are resistant to almost any treatment. Deep brain stimulation (DBS) holds promise as a new option for patients suffering from...

Sponsor: University of California, San FranciscoEnrolling: 121 location
Spinal Cord InjuriesNerve InjuryPain, Postoperative+6
RECRUITINGNCT05933083

MCNAIR Study: coMparative effeCtiveness of iN-person and teleheAlth cardIac Rehabilitation

Cardiac rehabilitation is a medically recommended program for patients with certain heart conditions. It includes exercise training, health education, and counseling....

Sponsor: University of California, San FranciscoEnrolling: 5165 locations
Myocardial InfarctionHeart Failure, SystolicHeart Valve Diseases+3
RECRUITINGNCT06754176

Full-Avoidance vs. Permissive/Regulated Drinking & Outcomes On Fibrillation

The goal of this study is to assess the short-term effects of minimal and moderate drinking on atrial fibrillation (AFib) episodes in a real-world population diagnosed with...

Sponsor: University of California, San FranciscoEnrolling: 1002 locations
Atrial Fibrillation (AF)Atrial Fibrillation (Paroxysmal)
RECRUITINGNCT05818605

Exercise Intolerance in Non-obstructive Hypertrophic Cardiomyopathy

The EXCITE-HCM study is a randomized, controlled, blinded clinical trial designed to evaluate the effect of moderate intensity exercise training versus usual physicial activity on...

Sponsor: University of California, San FranciscoEnrolling: 701 location
Hypertrophic Cardiomyopathy
RECRUITINGNCT06091527

Treating Major Depression With Yoga Mono-therapy

The goal of this single-center, single-blind, randomized, controlled, parallel group, interventional trial is to evaluate antidepressant efficacy of yoga monotherapy of 12-weeks...

Sponsor: University of California, San FranciscoEnrolling: 1801 location
Depression MildDepression Moderate
RECRUITINGPhase 2NCT05999383

Understanding the Clinical Pharmacology of Marijuana-Tobacco Co-administration

This is a crossover, randomized, double-blinded clinical pharmacology study enrolling dual cannabis-tobacco smokers to better understand the combined effects of co-administering...

Sponsor: University of California, San FranciscoEnrolling: 481 location
THCCannabisCannabis Use+3
RECRUITINGNCT07214467

Individualized Adaptive Deep Brain Stimulation in Opioid Use Disorder

The purpose of this study is to determine if personalized (adaptive) Deep Brain Stimulation (DBS) based upon invasive brain mapping is safe and can lead to better outcomes like...

Sponsor: University of California, San FranciscoEnrolling: 61 location
Substance Use Disorder (SUD)Opioid Use Disorder (OUD)
RECRUITINGPhase 4NCT05858632

Immune Spatial Features of Guselkumab Cutaneous Response

This study examines the effect of IL-23 blockade with Guselkumab on the immune cells of scalp psoriasis lesions.

Sponsor: University of California, San FranciscoEnrolling: 101 location
Psoriasis of Scalp
RECRUITINGNCT06940323

Pregnancy Registry, Infants, Serum/Milk Analysis (PRISMA)

PRISMA, is a pregnancy registry study, focused on comprehensively collecting information about pregnancy in women with chronic neurological conditions from across the United...

Sponsor: University of California, San FranciscoEnrolling: 2501 location
Multiple SclerosisClinically Isolated SyndromeNMOSD+1
RECRUITINGPhase 1 / Phase 2NCT02638701

Infliximab Therapy for Dolichoectactic Vertebrobasilar Aneurysms

Patients harboring dolichoectactic vertebrobasilar (DVB) aneurysms are at risk of suffering SAH, ischemic stroke, and/or brainstem compression and many patients are not offered...

Sponsor: University of California, San FranciscoEnrolling: 81 location
AneurysmStrokeVasculitis+1
RECRUITINGNCT07087184

Gauging Outcomes of Total Milk Ingestion on Lipid and gControl

Atherosclerotic cardiovascular disease remains the leading cause of death for adults in the United States. The cardiovascular impact of milk consumption remains a matter of...

Sponsor: University of California, San FranciscoEnrolling: 1001 location
Heart DiseasesCardiovascular Disease
RECRUITINGNCT06669949

Natural History of Sphingosine Phosphate Lyase Insufficiency Syndrome (SPLIS)

This is a prospective longitudinal natural history study with a retrospective cross-sectional arm aimed at determining the natural history of sphingosine phosphate lyase...

Sponsor: University of California, San FranciscoEnrolling: 281 location
Sphingosine Phosphate Lyase Insufficiency Syndrome (SPLIS)
RECRUITINGNCT04885179

SPL Insufficiency Syndrome (SPLIS)/NPHS14: a SPLIS Observational Study and Patient Registry (International)

This protocol aims to gather information about sphingosine phosphate lyase insufficiency syndrome (SPLIS), also known as NPHS14, and to create a SPLIS patient registry. Medical...

Sponsor: University of California, San FranciscoEnrolling: 1201 location
SphingolipidosesEnzyme Deficiency
RECRUITINGNCT07018076

Candidate Clinical Correlate of Prognostic Outcome for TB Study

As part of the ongoing efforts within the Rapid Research in Diagnostics Development for TB Network (R2D2 TB Network) study, the Candidate Clinical Correlate as Prognostic Outcome...

Sponsor: University of California, San FranciscoEnrolling: 7503 locations
Tuberculosis
RECRUITINGNCT04923958

Rapid Research in Diagnostics Development for TB Network

To reduce the burden of TB worldwide through more accurate, faster, simpler, and less expensive diagnosis of TB Every year, more than 3 million people with TB remain undiagnosed...

Sponsor: University of California, San FranciscoEnrolling: 2643616 locations
Tuberculosis
RECRUITINGPhase 2 / Phase 3NCT06441006

Program for Rifampicin-Resistant Disease With Stratified Medicine for Tuberculosis

PRISM-TB is an international, seamless, multicenter, open-label, randomized, controlled, pragmatic, stratified medicine, treatment shortening, multi-arm multi-stage (MAMS),...

Sponsor: University of California, San FranciscoEnrolling: 4006 locations
Tuberculosis, PulmonaryTuberculosis, Multidrug-ResistantTuberculosis, MDR
RECRUITINGNCT05567133

Risk Indicators of Sarcoidosis Evolution-Unified Protocol

The purpose of this study is to develop prediction models that can prognosticate patients with sarcoidosis using clinical data and blood markers that can be obtained during a...

Sponsor: University of California, San FranciscoEnrolling: 2002 locations
Sarcoidosis, Pulmonary
RECRUITINGPhase 2 / Phase 3NCT06633900

Naltrexone for Overdose Prevention

The goal of this clinical trial is to see if an injectable medicine called naltrexone can prevent fentanyl overdose deaths in people who use other drugs (cocaine,...

Sponsor: University of California, San FranciscoEnrolling: 1001 location
Overdose Accidental
RECRUITINGNCT07087145

Feasibility of HPV Testing With Mail-delivered Sample Collection Kits

People living with human immunodeficiency virus (PLWH) have an estimated 1.6-6.0 times increased risk of developing oropharyngeal cancer (OPC) compared with individuals in the...

Sponsor: University of California, San FranciscoEnrolling: 1351 location
HPV InfectionHIV InfectionsHPV-Related Malignancy
RECRUITINGNCT07236905

Improving Access to HIV Testing for Children in Uganda

The goal of this study is to learn if HIV screening testing can be done for children ages 18 months to 5 years by traditional healers in Southwestern Uganda. The main questions...

Sponsor: University of California, San FranciscoEnrolling: 4001 location
HIV (Human Immunodeficiency Virus)
RECRUITINGNCT06179498

Partner Navigation Intervention for Hepatitis C Treatment Among Young People Who Inject Drugs

The Partner Navigation Intervention Study is a randomized controlled study (RCT) to assess the efficacy and mechanism of action of the first behavioral intervention to increase...

Sponsor: University of California, San FranciscoEnrolling: 5001 location
Hepatitis C
RECRUITINGPhase 3NCT05690841

FocaL Mass Drug Administration for Vivax Malaria Elimination

FLAME is an open-label cluster-randomized controlled trial that aims to determine the effectiveness of focal mass drug administration (fMDA) to reduce the incidence of Plasmodium...

Sponsor: University of California, San FranciscoEnrolling: 75301 location
Plasmodium Vivax MalariaMalaria
RECRUITINGNCT07171164

A Study to Evaluate Community-Based Measures to Increase RSV Vaccine Use Among Latino Adults

In collaboration with community-based organizations, this study will focus on increasing RSV vaccine use among Latinos. The study will determine how effective community health...

Sponsor: University of California, San FranciscoEnrolling: 7501 location
Older Adults Without Any Specific Clinical ConditionSocial NetworksRSV Immunization+1
RECRUITINGNCT05619900

Registry of Patients Diagnosed With Lysosomal Storage Diseases

This is an international prospective and retrospective registry of patients with Lysosomal Storage Diseases (LSDs) to understand the natural history of the disease and the...

Sponsor: University of California, San FranciscoEnrolling: 2501 location
Mucopolysaccharidosis IMucopolysaccharidosis IIMucopolysaccharidosis IV A+5
RECRUITINGPhase 1NCT04532047

PEARL (PrEnAtal Enzyme Replacement Therapy for Lysosomal Storage Disorders)

For detailed information, please view our study website: https://pearltrial.ucsf.edu/ The investigators aims to determine the the maternal and fetal safety and feasibility of in...

Sponsor: University of California, San FranciscoEnrolling: 101 location
MPS IMPS IIMPS IVA+6

Showing 30 of 38 trials. The remainder are accessible through individual condition pages or directly on ClinicalTrials.gov.

How to Approach a Trial Listing

Each trial card above links to a dedicated page with the official ClinicalTrials.gov data plus a plain-English translation of the eligibility criteria. We translate technical terminology (ECOG performance status, hepatic function values, exclusionary lab thresholds) into language that a patient or caregiver can understand, but the original clinical text and the live ClinicalTrials.gov record always govern any actual eligibility decision.

Before contacting a trial site, write down questions for your treating physician using the framework on our 25 Questions guide. Discuss whether the trial fits your treatment plan, what the time commitment looks like, and whether your insurance will cover the standard-of-care portions. Trials are not a substitute for a treatment plan — they are an addition that needs medical guidance to evaluate.

Authoritative Resources

Verify any trial registration directly on ClinicalTrials.gov. For background on the FDA approval pathway that Phase 3 trials feed into, see the FDA drug approval process. For cancer-specific trial guidance, the National Cancer Institute publishes patient-oriented overviews. For global trial registrations beyond the U.S., the WHO ICTRP aggregates registries from around the world.

Frequently Asked Questions

How many clinical trials does University of California, San Francisco have on ClinicalTrials.gov?

University of California, San Francisco has 38 clinical trials registered on the federal ClinicalTrials.gov registry, of which 38 are actively recruiting participants right now. These counts come directly from the ClinicalTrials.gov API and are updated as the registry changes.

What conditions does University of California, San Francisco study?

University of California, San Francisco's registered trials cover 20 conditions on ClinicalTrials.gov, led by Glaucoma (3 trials), Tuberculosis (2 trials), Pompe Disease Infantile-Onset (2 trials), Wolman Disease (2 trials), Age-Related Macular Degeneration (2 trials). The complete condition list appears in the sidebar of this page; each condition links to a page listing every recruiting trial in that area, regardless of sponsor.

How do I join a University of California, San Francisco clinical trial?

Joining a clinical trial is a medical decision that should always involve your treating physician. Each trial page on this site includes the eligibility criteria translated into plain English alongside the official clinical text, plus the contact information that the sponsor has registered with ClinicalTrials.gov. Bring the trial information to your doctor before reaching out — they can review the full inclusion and exclusion criteria against your medical history and help you decide whether to pursue screening.

What does the trial phase mean?

Phase 1 trials test safety and dosing in small groups (often 20–80 healthy volunteers or patients). Phase 2 trials evaluate efficacy and side effects in larger groups (100–300 patients with the target condition). Phase 3 trials confirm efficacy and monitor safety in the largest groups (300–3,000+ patients) and form the basis of an FDA approval submission. Phase 4 studies happen after a treatment is approved, monitoring long-term safety and effectiveness in real-world use. Some trials register without a phase — common for device, behavioral, or observational studies.

Where does this trial data come from?

All trial data is pulled directly from the ClinicalTrials.gov API v2, the official federal trial registry maintained by the National Library of Medicine at NIH. Under FDAAA 801, most U.S. drug and device trials are required to register, making ClinicalTrials.gov the most comprehensive source. Sponsors are responsible for keeping their listings current; trial status can shift between data refreshes.

How This Sponsor Page Is Built

Every count on this page is derived directly from ClinicalTrials.gov API v2 records. Trial counts include all trials currently registered to this sponsor; the recruiting count reflects trials with status "Recruiting" or equivalent. Plain-English eligibility translations on each linked trial page preserve the original clinical text alongside an accessible version. Read the full methodology for the data pipeline and limitations.

Source: ClinicalTrials.gov API v2, maintained by the National Library of Medicine at NIH. Public domain. Cite as: "TrialFinderData. Data: ClinicalTrials.gov."

Medical disclaimer: This page is informational, not medical advice. Talk to your doctor about whether a clinical trial is right for you.

Last updated 2026-06-26 · 38 trials tracked for University of California, San Francisco.