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TrialFinderData is for informational purposes only and does not provide medical advice. Always talk to your doctor.

Updated June 2026 · ClinicalTrials.gov

University of Illinois at Chicago

Reviewed by TrialFinderData Editorial Team · Updated

15 clinical trials · 15 recruiting · OTHER

University of Illinois at Chicago has 15 clinical trials registered on ClinicalTrials.gov, with 15 actively recruiting participants. The trials listed below cover 20 conditions across the phases listed in the sidebar. Always discuss any specific trial with your physician before contacting a study site.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About University of Illinois at Chicago\'s Trial Portfolio

University of Illinois at Chicago is a non-industry sponsor (academic medical center, hospital, foundation, or research network). Non-industry sponsors often investigate novel approaches, rare conditions, and behavioral or surgical interventions that commercial sponsors may not prioritize.

15 of University of Illinois at Chicago's 15 registered trials are currently recruiting — roughly 100% of the portfolio. A high recruiting share usually points to an active research pipeline with multiple programs at the enrollment stage.

University of Illinois at Chicago's research footprint spans Sickle Cell Disease (2 trials), lung-cancer-screening (1), and physiological-reactivity-to-cues (1) as the top three conditions. The full condition list, sorted by trial count, is in the sidebar.

Not Applicable is the largest single phase in University of Illinois at Chicago's portfolio at 67% of registered trials. The full phase breakdown appears in the sidebar.

Trials by University of Illinois at Chicago

RECRUITINGNCT07408531

LUNG-07: Advancing Precision-Based Lung Cancer Screening: Implementation, AI-Guided Risk Stratification, and Biomarker...

This research study aims to investigate methods for enhancing lung cancer screening. The study will investigate whether an artificial intelligence (AI) tool, known as Sybil, can...

Sponsor: University of Illinois at ChicagoEnrolling: 25002 locations
Lung Cancer Screening
RECRUITINGNCT07647250

Pilot Study to Evaluate Targeted Physical Activity Among Pancreatic Cancer Patients Receiving Neoadjuvant Chemotherapy

Patients with pancreatic cancer receiving neoadjuvant chemotherapy often experience functional decline, treatment interruptions, and clinical deterioration, and these risks may be...

Sponsor: University of Illinois at ChicagoEnrolling: 251 location
Physiological Reactivity to CuesPhysical Exercise
RECRUITINGPhase 2NCT05344833

Post-Autologous Transplant Maintenance With Isatuximab and Lenalidomide in Minimal Residual Disease Positive Multiple...

This is a phase II study where patients will undergo isatuximab and lenalidomide maintenance if they are MRD-positive after Autologous Stem Cell Transplant (ASCT)

Sponsor: University of Illinois at ChicagoEnrolling: 502 locations
Multiple Myeloma
RECRUITINGNCT07355387

Home Based Functional Balance Intervention for Multiple Sclerosis

The study involves a two-arm, Phase 1, randomized controlled clinical trial designed to establish the feasibility and effects of a Functional Balance Intervention (FBI) on...

Sponsor: University of Illinois at ChicagoEnrolling: 751 location
Multiple SclerosisMultiple Sclerosis (MS) - Relapsing-remittingMultiple Sclerosis (MS) Primary Progressive+2
RECRUITINGNCT05067179

Analysis of Human ALS Tissues and Registry of ALS Patients

Amyotrophic Lateral Sclerosis (ALS), often referred to as Lou Gehrig's Disease, is a progressive, terminal condition of muscle weakness that is associated with degeneration of...

Sponsor: University of Illinois at ChicagoEnrolling: 401 location
Amyotrophic Lateral Sclerosis
RECRUITINGNCT06127602

The REACTplusNMES Trial: A Double-blinded RCT

The aim of this study is to compare the effectiveness of 6-weeks of reactive balance training (REACT) with and without neuromuscular electrical stimulation (NMES) to paretic lower...

Sponsor: University of Illinois at ChicagoEnrolling: 461 location
Stroke, IschemicStroke HemorrhagicStroke, Cerebrovascular
RECRUITINGNCT07387445

Feasibility and Acceptibility of a Multi-site Trial of Time Restircted Eating During Chemotheraply for Breast Cancer.

This study is being done to better understand how time restricted eating (eating all food in an 8 hour window) can help a person receiving chemotherapy treatment for breast...

Sponsor: University of Illinois at ChicagoEnrolling: 402 locations
Breast Cancer Early Stage Breast Cancer (Stage 1-3)Breast Neoplasm FemaleBreast Cancer
RECRUITINGNCT06823453

Reducing Overdose and Substance Use-related Stigma by Training Non-substance-using Friends and Family Members of People...

Fatal opioid overdoses are more frequent among populations with low access to harm reduction (HR) services and with high substance use-related stigma (which is a major barrier to...

Sponsor: University of Illinois at ChicagoEnrolling: 6001 location
Opioid Overdose PreventionPeople Who Use Opioids/People With Opioid Use Disorder (OUD)Reduction of Substance Use-related Stigma+2
RECRUITINGEarly Phase 1NCT07091318

CBTi for the Treatment of Insomnia in Type 1 Diabetes

The goal of this study is to learn if treating insomnia with a therapy intervention in people with type 1 diabetes will help to better control sugar levels, sleep, and quality of...

Sponsor: University of Illinois at ChicagoEnrolling: 151 location
Diabetes Mellitus Type 1Insomnia
RECRUITINGNCT06857071

Expanded Social Network Recruitment to HIV Testing (E-SNRHT) Intervention to Locate Undiagnosed Cases and Reduce...

In South Africa's large generalized HIV epidemic, male-to-female transmission comprises a large proportion of transmission events, but men are much less likely to seek HIV...

Sponsor: University of Illinois at ChicagoEnrolling: 24801 location
Undiagnosed HIV InfectionPopulations That Are Reluctant to Test for HIVLong-term Undiagnosed HIV Infection+3
RECRUITINGPhase 2NCT04442191

Convalescent Plasma as a Possible Treatment for COVID-19

Patients who are ill with COVID-19 may benefit from receiving convalescent plasma infusions containing antibodies from donors who have recovered from the disease and are proven to...

Sponsor: University of Illinois at ChicagoEnrolling: 501 location
COVID-19
RECRUITINGNCT07402811

Mindfulness-Based Intervention for Pain and Sleep in Adolescents and Young Adults With Sickle Cell Disease

This study examines the feasibility and acceptability of a mindfulness-based mobile intervention designed to support pain and sleep management among adolescents and young adults...

Sponsor: University of Illinois at ChicagoEnrolling: 201 location
Chronic PainSickle Cell DiseaseSleep Disturbance
RECRUITINGNCT06886477

Sickle Cell, Pain and Mediterranean Diet

The goal of this study is to compare pain levels in individuals with Sickle Cell Disease while following the Mediterranean Diet to pain levels while following their usual diet.

Sponsor: University of Illinois at ChicagoEnrolling: 301 location
Sickle CellSickle Cell DiseaseSickle Cell Disease Without Crisis+1
RECRUITINGPhase 2NCT04547439

Sleep, Diabetic Retinopathy and Melatonin

This study explores the use of melatonin in patients with diabetic retinopathy

Sponsor: University of Illinois at ChicagoEnrolling: 421 location
Diabetes MellitusDiabetic Retinopathy
RECRUITINGNCT07296952

Using Implementation Science to Adapt a Targeted Transportation Intervention for Patients With Diabetic Retinopathy...

This is a a type 3 hybrid effectiveness-implementation pilot study to evaluate the PRONTO-EYE intervention, a rideshare transportation program, in patients with diabetic...

Sponsor: University of Illinois at ChicagoEnrolling: 601 location
Diabetic Retinopathy (DR)

How to Approach a Trial Listing

Each trial card above links to a dedicated page with the official ClinicalTrials.gov data plus a plain-English translation of the eligibility criteria. We translate technical terminology (ECOG performance status, hepatic function values, exclusionary lab thresholds) into language that a patient or caregiver can understand, but the original clinical text and the live ClinicalTrials.gov record always govern any actual eligibility decision.

Before contacting a trial site, write down questions for your treating physician using the framework on our 25 Questions guide. Discuss whether the trial fits your treatment plan, what the time commitment looks like, and whether your insurance will cover the standard-of-care portions. Trials are not a substitute for a treatment plan — they are an addition that needs medical guidance to evaluate.

Authoritative Resources

Verify any trial registration directly on ClinicalTrials.gov. For background on the FDA approval pathway that Phase 3 trials feed into, see the FDA drug approval process. For cancer-specific trial guidance, the National Cancer Institute publishes patient-oriented overviews. For global trial registrations beyond the U.S., the WHO ICTRP aggregates registries from around the world.

Frequently Asked Questions

How many clinical trials does University of Illinois at Chicago have on ClinicalTrials.gov?

University of Illinois at Chicago has 15 clinical trials registered on the federal ClinicalTrials.gov registry, of which 15 are actively recruiting participants right now. These counts come directly from the ClinicalTrials.gov API and are updated as the registry changes.

What conditions does University of Illinois at Chicago study?

University of Illinois at Chicago's registered trials cover 20 conditions on ClinicalTrials.gov, led by Sickle Cell Disease (2 trials), lung-cancer-screening (1 trial), physiological-reactivity-to-cues (1 trial), physical-exercise (1 trial), Multiple Myeloma (1 trial). The complete condition list appears in the sidebar of this page; each condition links to a page listing every recruiting trial in that area, regardless of sponsor.

How do I join a University of Illinois at Chicago clinical trial?

Joining a clinical trial is a medical decision that should always involve your treating physician. Each trial page on this site includes the eligibility criteria translated into plain English alongside the official clinical text, plus the contact information that the sponsor has registered with ClinicalTrials.gov. Bring the trial information to your doctor before reaching out — they can review the full inclusion and exclusion criteria against your medical history and help you decide whether to pursue screening.

What does the trial phase mean?

Phase 1 trials test safety and dosing in small groups (often 20–80 healthy volunteers or patients). Phase 2 trials evaluate efficacy and side effects in larger groups (100–300 patients with the target condition). Phase 3 trials confirm efficacy and monitor safety in the largest groups (300–3,000+ patients) and form the basis of an FDA approval submission. Phase 4 studies happen after a treatment is approved, monitoring long-term safety and effectiveness in real-world use. Some trials register without a phase — common for device, behavioral, or observational studies.

Where does this trial data come from?

All trial data is pulled directly from the ClinicalTrials.gov API v2, the official federal trial registry maintained by the National Library of Medicine at NIH. Under FDAAA 801, most U.S. drug and device trials are required to register, making ClinicalTrials.gov the most comprehensive source. Sponsors are responsible for keeping their listings current; trial status can shift between data refreshes.

How This Sponsor Page Is Built

Every count on this page is derived directly from ClinicalTrials.gov API v2 records. Trial counts include all trials currently registered to this sponsor; the recruiting count reflects trials with status "Recruiting" or equivalent. Plain-English eligibility translations on each linked trial page preserve the original clinical text alongside an accessible version. Read the full methodology for the data pipeline and limitations.

Source: ClinicalTrials.gov API v2, maintained by the National Library of Medicine at NIH. Public domain. Cite as: "TrialFinderData. Data: ClinicalTrials.gov."

Medical disclaimer: This page is informational, not medical advice. Talk to your doctor about whether a clinical trial is right for you.

Last updated 2026-06-26 · 15 trials tracked for University of Illinois at Chicago.