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TrialFinderData is for informational purposes only and does not provide medical advice. Always talk to your doctor.

Updated May 2026 · ClinicalTrials.gov

Vanderbilt University Medical Center

17 clinical trials · 17 recruiting · OTHER

Vanderbilt University Medical Center has 17 clinical trials registered on ClinicalTrials.gov, with 17 actively recruiting participants. The trials listed below cover 20 conditions across the phases listed in the sidebar. Always discuss any specific trial with your physician before contacting a study site.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

About Vanderbilt University Medical Center\'s Trial Portfolio

Vanderbilt University Medical Center is a non-industry sponsor (academic medical center, hospital, foundation, or research network). Non-industry sponsors often investigate novel approaches, rare conditions, and behavioral or surgical interventions that commercial sponsors may not prioritize.

17 of Vanderbilt University Medical Center's 17 registered trials are currently recruiting — roughly 100% of the portfolio. A high recruiting share usually points to an active research pipeline with multiple programs at the enrollment stage.

Vanderbilt University Medical Center's research footprint spans Idiopathic Pulmonary Arterial Hypertension (2 trials), Heritable Pulmonary Arterial Hypertension (2), and Duchenne Muscular Dystrophy (2) as the top three conditions. The full condition list, sorted by trial count, is in the sidebar.

is the largest single phase in Vanderbilt University Medical Center's portfolio at 35% of registered trials. The full phase breakdown appears in the sidebar.

Trials by Vanderbilt University Medical Center

RECRUITINGNCT07529691

Survey on Physical Activity and Qualify of Life in Fibromuscular Dysplasia

Fibromuscular dysplasia (FMD) is a disease of the arteries that is not due to plaque build-up or inflammation. While some patients with FMD are health, some may experience heart...

Sponsor: Vanderbilt University Medical CenterEnrolling: 20001 location
Fibromuscular Dysplasia of ArteriesFibromuscular DysplasiaSpontaneous Coronary Artery Dissection
RECRUITINGNCT03042988

Overnight Trials With Heat Stress in Autonomic Failure Patients With Supine Hypertension

Patients with autonomic failure are characterized by disabling orthostatic hypotension (low blood pressure on standing), and at least half of them also have high blood pressure...

Sponsor: Vanderbilt University Medical CenterEnrolling: 201 location
HypertensionPure Autonomic FailureMultiple System Atrophy+1
RECRUITINGNCT05584722

Risk and Resilience in Pulmonary Arterial Hypertension and Genetically Susceptible Individuals

Pulmonary arterial hypertension (PAH) is a severe disease with a delayed diagnosis and markedly elevated mortality. High-risk populations, such as those with known genetic...

Sponsor: Vanderbilt University Medical CenterEnrolling: 1501 location
Idiopathic Pulmonary Arterial HypertensionHeritable Pulmonary Arterial HypertensionUnaffected Mutation Carriers: Healthy Participants With a Known BMPR2 Gene Mutation and Normal Pulmonary Pressure and RV Function on Echo+1
RECRUITINGNCT01884051

Hormonal, Metabolic, and Signaling Interactions in PAH

Our hypothesis is that optimal treatment of the dysfunctional metabolic pathways which underlie PAH will improve pulmonary vascular function and consequences of the disease.

Sponsor: Vanderbilt University Medical CenterEnrolling: 18991 location
Idiopathic Pulmonary Arterial HypertensionHeritable Pulmonary Arterial HypertensionScleroderma Associated Pulmonary Arterial Hypertension+1
RECRUITINGNCT06124196

Wearable Technology to Evaluate Hyperglycemia and HRV in DMD

Duchenne muscular dystrophy (DMD) is an X-linked disorder that causes muscle wasting, cardiopulmonary failure, and premature death. Heart failure is a leading cause of death in...

Sponsor: Vanderbilt University Medical CenterEnrolling: 801 location
Duchenne Muscular Dystrophy
RECRUITINGNCT06093100

Wearable Technology to Evaluate Hyperglycemia and HRV in DMD - Longitudinal Aim

Duchenne Muscular Dystrophy (DMD) is an X-linked disorder that causes muscle wasting, cardiopulmonary failure, and premature death. Heart failure is a leading cause of death in...

Sponsor: Vanderbilt University Medical CenterEnrolling: 101 location
Duchenne Muscular Dystrophy
RECRUITINGNCT06077201

Home-Based Cardiac Rehabilitation Using a Novel Mobile Health Exercise Regimen Following Transcatheter Heart Valve...

The vast majority of cardiac rehabilitation eligible individuals do not participate in center based cardiac rehabilitation (CBCR). While steps to encourage participation in CBCR...

Sponsor: Vanderbilt University Medical CenterEnrolling: 2401 location
Valvular Heart Disease
RECRUITINGPhase 3NCT04801589

Goal-Directed Sedation in Mechanically Ventilated Infants and Children

Ventilated pediatric patients are frequently over-sedated and the majority suffer from delirium, a form of acute brain dysfunction that is an independent predictor of increased...

Sponsor: Vanderbilt University Medical CenterEnrolling: 3721 location
DeliriumCritical IllnessSedation Complication+2
RECRUITINGNCT04725409

Neural Correlates of Psychiatric Disorders

This ClincialTrials.gov record originally corresponded to the protocol approved under IRB # 202370. The study was expanded to include stimulation and recordings approved under new...

Sponsor: Vanderbilt University Medical CenterEnrolling: 1001 location
Psychiatric DisorderMemory Disorders
RECRUITINGNCT05880225

Reciprocal Imitation Training and Musical Rhythm Sensitivity in Autistic Toddlers

The primary goal of this study is to examine rhythm sensitivity as a predictor of response to naturalistic developmental behavioral intervention (NDBIs) in autistic toddlers....

Sponsor: Vanderbilt University Medical CenterEnrolling: 401 location
AutismAutism Spectrum Disorder
RECRUITINGNCT06852950

Continuous Glucose Monitoring for Outpatient Diabetes Management After Hospital Discharge

This study aims to improve patient awareness of the utility of continuous glucose monitoring systems in blood glucose monitoring and to improve patient satisfaction regarding...

Sponsor: Vanderbilt University Medical CenterEnrolling: 601 location
Type 2 Diabetes Mellitus (T2DM)Type 1 Diabetes Mellitus (T1DM)Hyperglycemia
RECRUITINGNCT06516614

Sleep Coach for Adolescents With Type 1 Diabetes

The goal of this work is to conduct a randomized trial evaluating the effects of a behavioral intervention to increase sleep duration and quality for adolescents with type 1...

Sponsor: Vanderbilt University Medical CenterEnrolling: 1501 location
Type 1 Diabetes
RECRUITINGPhase 2NCT04941599

2-Hydroxybenzylamine (2-HOBA) to Reduce HDL Modification and Improve HDL Function in Familial Hypercholesterolemia (FH)

The Investigators will test the hypothesis that 2-HOBA will reduce modification of HDL and LDL and improve HDL function in humans with heterozygous FH. The Investigators plan to...

Sponsor: Vanderbilt University Medical CenterEnrolling: 721 location
Familial Hypercholesterolemia
RECRUITINGNCT05501236

Ansa Cervicalis and Hypoglossal Nerve Stimulation in OSA

Polysomnography (PSG) and drug-induced sleep endoscopy (DISE) are widely used diagnostic studies for assessing obstructive sleep apnea (OSA) severity and collapse patterns of the...

Sponsor: Vanderbilt University Medical CenterEnrolling: 1001 location
Obstructive Sleep Apnea
RECRUITINGPhase 2NCT05215327

High vs. Standard Dose Influenza Vaccine in Lung Allograft Recipients

Lung allograft recipients have a higher burden of influenza disease and greater associated morbidity and mortality compared with healthy controls. Induction and early maintenance...

Sponsor: Vanderbilt University Medical CenterEnrolling: 2701 location
Immunization; InfectionTransplantation InfectionInfluenza
RECRUITINGPhase 2NCT07192458

High vs. Standard Dose Influenza Vaccines in Lung Transplant (Repeater)

This will be a follow-up study to the "Comparison of High Dose vs. Standard Dose Influenza Vaccine in Lung Allograft Recipient" study (DMID Protocol Number 22-0014) at Vanderbilt...

Sponsor: Vanderbilt University Medical CenterEnrolling: 601 location
Immunization; Infection|Transplantation Infection|InfluenzaInfluenza
RECRUITINGPhase 4NCT06526117

Stroke Prevention in Nigeria 2 Trial

The primary goal of this study is to complete a multicenter single-arm, type I hybrid trial to assess the effectiveness of hydroxyurea therapy for primary stroke prevention in...

Sponsor: Vanderbilt University Medical CenterEnrolling: 2202 locations
Sickle Cell DiseaseStroke

How to Approach a Trial Listing

Each trial card above links to a dedicated page with the official ClinicalTrials.gov data plus a plain-English translation of the eligibility criteria. We translate technical terminology (ECOG performance status, hepatic function values, exclusionary lab thresholds) into language that a patient or caregiver can understand, but the original clinical text and the live ClinicalTrials.gov record always govern any actual eligibility decision.

Before contacting a trial site, write down questions for your treating physician using the framework on our 25 Questions guide. Discuss whether the trial fits your treatment plan, what the time commitment looks like, and whether your insurance will cover the standard-of-care portions. Trials are not a substitute for a treatment plan — they are an addition that needs medical guidance to evaluate.

Authoritative Resources

Verify any trial registration directly on ClinicalTrials.gov. For background on the FDA approval pathway that Phase 3 trials feed into, see the FDA drug approval process. For cancer-specific trial guidance, the National Cancer Institute publishes patient-oriented overviews. For global trial registrations beyond the U.S., the WHO ICTRP aggregates registries from around the world.

Frequently Asked Questions

How many clinical trials does Vanderbilt University Medical Center have on ClinicalTrials.gov?

Vanderbilt University Medical Center has 17 clinical trials registered on the federal ClinicalTrials.gov registry, of which 17 are actively recruiting participants right now. These counts come directly from the ClinicalTrials.gov API and are updated as the registry changes.

What conditions does Vanderbilt University Medical Center study?

Vanderbilt University Medical Center's registered trials cover 20 conditions on ClinicalTrials.gov, led by Idiopathic Pulmonary Arterial Hypertension (2 trials), Heritable Pulmonary Arterial Hypertension (2 trials), Duchenne Muscular Dystrophy (2 trials), Influenza (2 trials), fibromuscular-dysplasia-of-arteries (1 trial). The complete condition list appears in the sidebar of this page; each condition links to a page listing every recruiting trial in that area, regardless of sponsor.

How do I join a Vanderbilt University Medical Center clinical trial?

Joining a clinical trial is a medical decision that should always involve your treating physician. Each trial page on this site includes the eligibility criteria translated into plain English alongside the official clinical text, plus the contact information that the sponsor has registered with ClinicalTrials.gov. Bring the trial information to your doctor before reaching out — they can review the full inclusion and exclusion criteria against your medical history and help you decide whether to pursue screening.

What does the trial phase mean?

Phase 1 trials test safety and dosing in small groups (often 20–80 healthy volunteers or patients). Phase 2 trials evaluate efficacy and side effects in larger groups (100–300 patients with the target condition). Phase 3 trials confirm efficacy and monitor safety in the largest groups (300–3,000+ patients) and form the basis of an FDA approval submission. Phase 4 studies happen after a treatment is approved, monitoring long-term safety and effectiveness in real-world use. Some trials register without a phase — common for device, behavioral, or observational studies.

Where does this trial data come from?

All trial data is pulled directly from the ClinicalTrials.gov API v2, the official federal trial registry maintained by the National Library of Medicine at NIH. Under FDAAA 801, most U.S. drug and device trials are required to register, making ClinicalTrials.gov the most comprehensive source. Sponsors are responsible for keeping their listings current; trial status can shift between data refreshes.

How This Sponsor Page Is Built

Every count on this page is derived directly from ClinicalTrials.gov API v2 records. Trial counts include all trials currently registered to this sponsor; the recruiting count reflects trials with status "Recruiting" or equivalent. Plain-English eligibility translations on each linked trial page preserve the original clinical text alongside an accessible version. Read the full methodology for the data pipeline and limitations.

Source: ClinicalTrials.gov API v2, maintained by the National Library of Medicine at NIH. Public domain. Cite as: "TrialFinderData. Data: ClinicalTrials.gov."

Medical disclaimer: This page is informational, not medical advice. Talk to your doctor about whether a clinical trial is right for you.

Last updated 2026-05-08 · 17 trials tracked for Vanderbilt University Medical Center.

For this entity, the underlying data on this page comes from the NIH ClinicalTrials.gov registry. The breakdown above is the federal record; the paragraphs below add the per-entity context that makes the headline numbers usable for a real decision rather than just a data lookup.

The methodology behind every numeric value on this page is publicly documented on the the NIH ClinicalTrials.gov registry portal and described in detail on this site’s methodology page. Refresh cadence varies by underlying series; the page surfaces the as-of date for each number so readers can trace any figure back to the source release.

Practical use of this page is in combination with the comparison and ranking pages elsewhere on the site, which surface the same data for this entity’s peers within active and historical clinical trials. A single-entity reading without peer context can be misleading when an entity is an outlier on one axis but typical on another.