Serial Magnetic Resonance Imaging for the Prediction of Radiation-Induced Changes in Normal Tissue of Patients With Oral Cavity or Skull Base Tumors

Who May Qualify: All Cohorts: - Patients older than 18 years of age - Patients with good performance status (ECOG score 0-2) - Patients willing to give written willing to sign a consent form. Cohort 1 (Individuals without ORN or MRONJ): - Patients with histologically proven malignant neoplasms of the oral cavity, oropharynx or skull base. - Patients currently dispositioned to treatment with radiotherapy and/or antiresorptive or antiangiogenic medication therapy Cohort 2 (Individuals with ORN or MRONJ): - Patients with a clinical diagnosis of ORN or MRONJ following treatment for cancer - Patients previously dispositioned to treatment with radiotherapy and/or antiresorptive or antiangiogenic medication therapy Who Should NOT Join This Trial: - Patients unable to tolerate DW-MRI or DCE-MRI or having an estimated GFR \< 30ml/min/1.73m2. - Patients with contraindication to MRI (e.g. non-MRI compatible metallic implants) Always talk to your doctor about whether this trial is right for you.