RECRUITINGOBSERVATIONAL
Cardiogenic Shock Working Group Registry
About This Trial
The Cardiogenic Shock Working Group is a multicenter registry where we collect de-identified clinical variables from the medical records and follow-up phone calls of shock patients from multiple institutions and centralize this data to a single registry for analysis of clinical outcomes.
Who May Be Eligible (Plain English)
Who May Qualify:
- Patients must have cardiogenic shock.
Cardiogenic shock is defined by at least one of the two categories below:
1. At least 2 of the following concurrently at any point during the index hospitalization:
- Cardiac Index \< 2.2
- PAPI \< 1.0
- Cardiac Power Output ≤ 0.6
- MAP \< 60mmHg or a \>30mmHg drop in MAP from baseline
- SBP \< 90mmHg or a \>30mmHg drop in SBP from baseline
- Pulse \> 100
2. Require at least one acute mechanical circulatory support device, vasopressor or inotrope to maintain values above the above target.
Post-cardiotomy patients must meet the inclusion criteria 72 hours after their surgery to be included in this registry.
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* Patients must have cardiogenic shock.
Cardiogenic shock is defined by at least one of the two categories below:
1. At least 2 of the following concurrently at any point during the index hospitalization:
* Cardiac Index \< 2.2
* PAPI \< 1.0
* Cardiac Power Output ≤ 0.6
* MAP \< 60mmHg or a \>30mmHg drop in MAP from baseline
* SBP \< 90mmHg or a \>30mmHg drop in SBP from baseline
* Pulse \> 100
2. Require at least one acute mechanical circulatory support device, vasopressor or inotrope to maintain values above the above target.
Post-cardiotomy patients must meet the inclusion criteria 72 hours after their surgery to be included in this registry.
Treatments Being Tested
DRUG
Vasopressor
The vasopressors include phenylephrine, norepinephrine, epinephrine, dopamine and vasopressin.
DRUG
Inotrope
Inotropes include dobutamine and milrinone.
DEVICE
Acute Mechanical Circulatory Support Devices
Acute Mechanical Circulatory Support devices include ECMO (VV), ECMO (VA), Impella CP, Impella 2.5, Impella 5.0, Impella 5.5, Impella RP, IABP, Centrimag, Tandem Heart and ProTek Duo.
Locations (16)
Cleveland Clinic Florida
Weston, Florida, United States
Northwestern Medicine
Chicago, Illinois, United States
University of Chicago
Chicago, Illinois, United States
Maine Medical Center
Portland, Maine, United States
Tufts Medical Center
Boston, Massachusetts, United States
Beth Israel Deaconess Medical Center
Boston, Massachusetts, United States
Hackensack Meridian Health
Hackensack, New Jersey, United States
Columbia University Irving Medical Center
New York, New York, United States
Providence St. Vincent Heart Clinic
Portland, Oregon, United States
Allegheny General Hospital
Pittsburgh, Pennsylvania, United States
University Of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, United States
Baylor Scott & White Advanced Heart Failure Clinic
Dallas, Texas, United States
University of Texas Medical Branch
Galveston, Texas, United States
Houston Methodist Hospital
Houston, Texas, United States
Inova Health System
Falls Church, Virginia, United States
University of Washington Medical Center
Seattle, Washington, United States