RECRUITINGOBSERVATIONAL
Pancreatic Cancer Detection Consortium
Early Detection of Pancreatic Cancer: Prospective Study
About This Trial
This study aims to prospective validate an exosome-based miRNA signature for noninvasive and early detection of pancreatic ductal adenocarcinoma.
Who May Be Eligible (Plain English)
Who May Qualify:
- Histological diagnosis of pancreatic ductal adenocarcinoma, stages I-IV (TNM classification, 8th edition)
- Received standard diagnostic and staging procedures as per local guidelines, and at least one sample was drawn before receiving any curative-intent treatment.
- Imaging- or endoscopy-based proof of lack of pancreatic ductal adenocarcinoma at the time of sampling (Non-disease controls)
Who Should NOT Join This Trial:
- Lack of written willing to sign a consent form.
Always talk to your doctor about whether this trial is right for you.
Original Eligibility Criteria
View original clinical language
Inclusion Criteria:
* Histological diagnosis of pancreatic ductal adenocarcinoma, stages I-IV (TNM classification, 8th edition)
* Received standard diagnostic and staging procedures as per local guidelines, and at least one sample was drawn before receiving any curative-intent treatment.
* Imaging- or endoscopy-based proof of lack of pancreatic ductal adenocarcinoma at the time of sampling (Non-disease controls)
Exclusion Criteria:
* Lack of written informed consent.
Treatments Being Tested
DIAGNOSTIC_TEST
PANcreatic cancer Exosome Early detectiON (PANXEON)
This test will utilize quantitative reverse transcriptase polymerase chain reaction (qRT-PCR) to quantify the expression levels of 5 cell-free and 8 exosome-miRNAs in plasma samples obtained from patients with pancreatic ductal adenocarcinoma and from individuals without it
Locations (11)
Translational Genomics Research Institute
Phoenix, Arizona, United States
Honorhealth
Scottsdale, Arizona, United States
City of Hope Medical Center
Monrovia, California, United States
Hoag Center
Newport Beach, California, United States
OSF HealthCare
Peoria, Illinois, United States
Ochsner Medical Center
Jefferson, Louisiana, United States
Atlantic Health System
Morristown, New Jersey, United States
Piedmont Medical Center
Rock Hill, South Carolina, United States
Medical College of Wisconsin
Milwaukee, Wisconsin, United States
Nagoya University
Nagoya, Japan
Asan Medical Center
Seoul, South Korea