Neoadjuvant Chemoimmunotherapy Followed by Surgery and Postoperative Radioimmunotherapy

Who May Qualify: - Ages 18-75; - Radical operation for esophageal cancer; - Esophageal squamous cell carcinoma was confirmed by postoperative pathology; . Preoperative imaging (enhanced cervical, thoracoabdominal CT+ bone scan) and postoperative pathological evaluation were performed, and the stage was pIIB-IVA (AJCC eighth edition staging criteria: T≥3 or N+). - More than or equal to 12 lymph nodes were surgically removed; - Postoperative ECOG score 0-1, able to tolerate postoperative adjuvant radiotherapy and immunotherapy; - willing to sign a consent form signed by patient or family member. Who Should NOT Join This Trial: - Less than 18 years old, more than 75 years old; - did not receive radical resection of esophageal cancer, including palliative resection; - Postoperative pathology showed non-esophageal squamous cell carcinoma; - After preoperative imaging (enhanced cervical, thoracoabdominal CT+ bone scan) and postoperative pathological evaluation, the stage was pI, IIA, IVB (AJCC eighth edition staging standard); e. Less than 12 lymph nodes were surgically removed; - Postoperative ECOG score 2-3 points, unable to tolerate postoperative adjuvant radiotherapy and immunotherapy; - The patient or family member did not sign the willing to sign a consent form. Always talk to your doctor about whether this trial is right for you.