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Esophageal Squamous Cell Carcinoma Clinical Trials

Reviewed by TrialFinderData Editorial Team · Updated

13 recruiting trials for Esophageal Squamous Cell Carcinoma. Eligibility criteria explained in plain English.

TrialFinderData lists 13 Esophageal Squamous Cell Carcinoma clinical trials drawn from ClinicalTrials.gov, all of which are currently recruiting participants.

Across the trials that carry a phase, Phase 2 is the largest group at 67% (6 studies); the largest phase groups are Phase 2: 6, Phase 3: 3.

Research is led by Sichuan University (2), University Hospital, Angers (1), Cofactor Genomics, Inc. (1), among the most active sponsors registered for these trials.

The most frequently studied intervention is Cisplatin (drug, 3 trials), followed by Tislelizumab, Nab paclitaxel.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
13
Total Trials
13
Recruiting Now
3
Phase 3 Trials
10
Sponsors

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Recruiting Trials

Clinical trial data sourced from the ClinicalTrials.gov registry, maintained by the National Library of Medicine. Always consult your doctor before considering any clinical trial.

RECRUITINGNCT06971848

Evaluation of Skin Tests in Biotherapy Allergies

Biotherapies are biological (extracted from an organism or living tissue) or biotechnological drugs used in the treatment of multiple conditions, such as autoimmune inflammatory...

Sponsor: University Hospital, AngersEnrolling: 701 location
RECRUITINGNCT04510129

A Multicenter Cancer Biospecimen Collection Study

This study will collect de-identified tumor samples, with correlated clinical/demographic data and tissue histology, from patients selected or scheduled for pre-treatment tumor...

Sponsor: Cofactor Genomics, Inc.Enrolling: 16501 location
RECRUITINGPhase 3NCT06022861

A Study to Compare the Efficacy and Safety of LY01015 and Opdivo® Combined Respectively With Chemotherapy in Advanced...

This is a randomized, double-blind, multicenter, Phase 3 study to compare the efficacy and safety of LY01015 and Opdivo®(Nivolumab Injection)combined respectively with...

Sponsor: Shandong Boan Biotechnology Co., LtdEnrolling: 5101 location
RECRUITINGPhase 2NCT06165380

Cardenilimab Combined With Chemotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma

The goal of this trial is to test the efficacy and safety of cardenilimab combined with chemotherapy in the conversion therapy of locally advanced unresectable esophageal squamous...

Sponsor: Li ZhangEnrolling: 431 location
RECRUITINGPhase 2NCT07152678

Brachytherapy With Radiotherapy and Immunotherapy: Guided HDR Trial in Esophageal Squamous Cell Carcinoma

The goal of this clinical trial is to learn if adding high-dose-rate (HDR) brachytherapy can improve outcomes in patients with locally advanced esophageal squamous cell carcinoma...

Sponsor: National Taiwan University HospitalEnrolling: 601 location
RECRUITINGPhase 2NCT07519486

Intensive Nutritional Support in Conversion Therapy for Locally Advanced Unresectable ESCC

Malnutrition is highly prevalent in patients with upper gastrointestinal tumors, which may negatively impact treatment tolerance and anti-tumor immune responses. This study aims...

Sponsor: Sichuan UniversityEnrolling: 1181 location
RECRUITINGPhase 2NCT07086469

Surufatinib in Combination With Neoadjuvant Chemo-immunotherapy and Concurrent Chemoradiotherapy for Patients With...

The combination of surufatinib with neoadjuvant chemo-immunotherapy and definitive concurrent chemoradiotherapy represents a promising new therapeutic strategy that may further...

Sponsor: Sun Yat-sen UniversityEnrolling: 691 location
RECRUITINGPhase 3NCT05919030

A Study of Chemoradiation in Combination with Tislelizumab As First Line Treatment in Participants with Advanced...

This study is a multicentre, randomised, parallel-controlled, open-label, 3 phase clinical trial. The subjects were untreated, unresectable locally advanced, recurrent or...

Sponsor: Renmin Hospital of Wuhan UniversityEnrolling: 1551 location
RECRUITINGNCT06408584

Short-course Hypofractionated Radiotherapy in Combination With Raltitrexed and Tislelizumab

The goal of this observational study was to explore the safety and efficacy of short course hypofractionated radiotherapy combined with Raltitrexed and Tislelizumab in the...

Sponsor: Anhui Provincial HospitalEnrolling: 251 location
RECRUITINGPhase 3NCT06190782

Local Therapy for Oligometastatic ESCC Patients Treated With PD-1 Inhibitor

Patients with oligometastatic squamous cell carcinoma were enrolled and randomly assigned to receive either PD-1 inhibitor +/- chemotherapy combined with local therapy or PD-1...

Sponsor: Fudan UniversityEnrolling: 3541 location
RECRUITINGPhase 2NCT06446726

Low-dose Radiation Combined With Neoadjuvant Immunochemotherapy for Esophageal Squamous Cell Carcinoma

This study aims to investigate the efficacy and safety of low-dose radiation combined with neoadjuvant chemotherapy and immunotherapy in the treatment of locally advanced thoracic...

Sponsor: Sichuan UniversityEnrolling: 301 location
RECRUITINGNCT04290806

Registry Platform Gastric/Esophageal Cancer (SAPHIR)

The registry aims to collect and analyse information on the antineoplastic treatment of patients with metastatic esophageal, gastric or gastroesophageal junction cancer, treated...

Sponsor: iOMEDICO AGEnrolling: 19001 location
RECRUITINGPhase 2NCT06354140

PPIO-008 Tislelizumab Combined With S-1 in Patients With ypT+N0 ESCC After Radical Resection With Neoadjuvant STUDY

To explore the safety and efficacy of Tegafur combined with tislelizumab in patients with esophageal squamous cell carcinoma with residual primary lesion and node-negative after...

Sponsor: Daping Hospital and the Research Institute of Surgery of the Third Military Medical UniversityEnrolling: 451 location

Frequently Asked Questions

There are currently 13 clinical trials for Esophageal Squamous Cell Carcinoma, with 13 actively recruiting participants. These include trials across all phases from early-stage Phase 1 to late-stage Phase 3.

To join a clinical trial for Esophageal Squamous Cell Carcinoma, review the eligibility criteria on the trial detail pages, then talk to your doctor about whether a trial is right for you. Your doctor can help you evaluate the potential benefits and risks.

Phase 3 trials are large-scale studies that test whether a treatment is effective and monitor side effects. There are 3 Phase 3 trials for Esophageal Squamous Cell Carcinoma, representing treatments closest to potential FDA approval.

Clinical trials follow strict safety protocols overseen by Institutional Review Boards (IRBs) and the FDA. Participants are monitored closely and can withdraw at any time. Always discuss risks and benefits with your healthcare provider before enrolling.

Sources: ClinicalTrials.gov, FDA
Last updated:

Trial data sourced from the ClinicalTrials.gov API. This site does not provide medical advice, always talk to your doctor about clinical trial participation.