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TrialFinderData is for informational purposes only and does not provide medical advice. Always talk to your doctor.

Diffuse Cutaneous Systemic Sclerosis Clinical Trials

6 recruiting trials for Diffuse Cutaneous Systemic Sclerosis. Eligibility criteria explained in plain English.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
6
Total Trials
6
Recruiting Now
1
Phase 3 Trials
6
Sponsors

Recruiting Trials

Clinical trial data sourced from the ClinicalTrials.gov registry, maintained by the National Library of Medicine. Always consult your doctor before considering any clinical trial.

RECRUITINGPhase 2NCT07287670

EncompaSSc: Evaluation of MTX-474 in Participants With Diffuse Cutaneous Systemic Sclerosis (dcSSc)

A Phase 2 Randomized, Double-blind, Placebo-Controlled Study of the Safety and Efficacy of MTX-474 in Participants with Diffuse Cutaneous Systemic Sclerosis (dcSSc)

Sponsor: Mediar TherapeuticsEnrolling: 855 locations
RECRUITINGPhase 2NCT06375005

Efficacy and Safety of Telitacicept in the Treatment of Systemic Sclerosis

This study is a prospective, open-label, randomized, controlled, multi-center clinical trial. The aim of this study is to investigate the efficacy and safety of Telitacicept in...

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityEnrolling: 389 locations
RECRUITINGPhase 2NCT06470048

A Clinical Study to Evaluate Ianalumab in Participants With Diffuse Cutaneous Systemic Sclerosis

The purpose of this study is to evaluate efficacy, safety and tolerability of s.c. ianalumab administered in participants with diffuse cutaneous systemic sclerosis relative to...

Sponsor: Novartis PharmaceuticalsEnrolling: 20020 locations
RECRUITINGPhase 2NCT05149768

Open Label Extension Study of Brentuximab Vedotin in Early dcSSc

The purpose of this study is to assess safety and efficacy of Brentuximab vedotin, a CD30-directed antibody-drug conjugate, in patients with active diffuse cutaneous systemic...

Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph'sEnrolling: 111 location
RECRUITINGPhase 3NCT06936215

Safety and Efficacy of Baricitinib on Skin Tightening in Diffuse Cutaneous Systemic Sclerosis: A Comparative Study With...

Systemic sclerosis (SSc) is a systemic autoimmune disease. It causes progressive skin tightening, pulmonary fibrosis, organ damage and many other physical dysfunctions. It is...

Sponsor: Bangabandhu Sheikh Mujib Medical University, Dhaka, BangladeshEnrolling: 241 location
RECRUITINGPhase 1 / Phase 2NCT07473154

Controlling Hyperactive Immunity With Long-lived Lymphocytes

This study is a Phase 1/2, open-label clinical trial to test an experimental treatment called QEL-005 in adults with two autoimmune conditions: diffuse cutaneous systemic...

Sponsor: Quell Therapeutics LimitedEnrolling: 166 locations

Frequently Asked Questions

There are currently 6 clinical trials for Diffuse Cutaneous Systemic Sclerosis, with 6 actively recruiting participants. These include trials across all phases from early-stage Phase 1 to late-stage Phase 3.

To join a clinical trial for Diffuse Cutaneous Systemic Sclerosis, review the eligibility criteria on the trial detail pages, then talk to your doctor about whether a trial is right for you. Your doctor can help you evaluate the potential benefits and risks.

Phase 3 trials are large-scale studies that test whether a treatment is effective and monitor side effects. There are 1 Phase 3 trials for Diffuse Cutaneous Systemic Sclerosis, representing treatments closest to potential FDA approval.

Clinical trials follow strict safety protocols overseen by Institutional Review Boards (IRBs) and the FDA. Participants are monitored closely and can withdraw at any time. Always discuss risks and benefits with your healthcare provider before enrolling.

Sources: ClinicalTrials.gov, FDA
Last updated:

Trial data sourced from the ClinicalTrials.gov API. This site does not provide medical advice, always talk to your doctor about clinical trial participation.

The this entity record above pulls directly from the NIH ClinicalTrials.gov registry. What follows is the per-entity context — how this entity sits in the broader U.S. clinical trials and research registries distribution and which underlying factors drive the headline numbers.

Every number on this page links back to the NIH ClinicalTrials.gov registry; the methodology page describes the inputs, refresh cadence, and known limitations of the underlying data product.

For readers using this page as a decision input, the related-entity pages elsewhere on the site provide the comparison set. The most useful comparison for this entity is typically a peer within active and historical clinical trials with similar size, similar exposure, or similar geography — not the national-level summary alone.