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Esophageal Adenocarcinoma Clinical Trials

Reviewed by TrialFinderData Editorial Team · Updated

11 recruiting trials for Esophageal Adenocarcinoma. Eligibility criteria explained in plain English.

TrialFinderData lists 11 Esophageal Adenocarcinoma clinical trials drawn from ClinicalTrials.gov, all of which are currently recruiting participants.

Across the trials that carry a phase, Phase 1 is the largest group at 57% (4 studies); the largest phase groups are Phase 1: 4, Phase 2: 2, Phase 1 / Phase 2: 1.

Research is led by Yale University (1), Masaryk Memorial Cancer Institute (1), Dispatch Biotherapeutics (1), among the most active sponsors registered for these trials.

The most frequently studied intervention is Sequential cytoreductive intervention (procedure, 1 trial), followed by Signatera Genome ultra-sensitive ctDNA blood test, NGS sequencing of mutations selected based on sequencing of primary tumors.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
11
Total Trials
11
Recruiting Now
0
Phase 3 Trials
10
Sponsors

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Recruiting Trials

Clinical trial data sourced from the ClinicalTrials.gov registry, maintained by the National Library of Medicine. Always consult your doctor before considering any clinical trial.

RECRUITINGPhase 2NCT07282912

Trial Comparing Standard of Care Therapy With and Without Sequential Cytoreductive Intervention for Patients With...

This is a randomized, open label, single-center, phase 2, randomized controlled trial of sequential cytoreductive intervention versus standard of care therapy for patients with...

Sponsor: Yale UniversityEnrolling: 541 location
RECRUITINGNCT07660627

Determining Minimal Residual Disease Using ctDNA Deep Sequencing

Preoperative neoadjuvant chemotherapy is the standard treatment for locally advanced gastrointestinal tumours. However, not all patients respond to preoperative treatment. Early...

Sponsor: Masaryk Memorial Cancer InstituteEnrolling: 341 location
RECRUITINGPhase 1NCT07544589

A Phase 1 Study Evaluating DISP-10 in Participants With Advanced Gastrointestinal Cancers

This is a Phase 1, multicenter, open-label study of DISP-10, a combination therapy consisting of DV-10 (adenovirus) and idecabtagene vicleucel (ide-cel, BCMA-directed chimeric...

Sponsor: Dispatch BiotherapeuticsEnrolling: 663 locations
RECRUITINGPhase 1 / Phase 2NCT06324357

Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to...

This study is open to adults aged 18 years and older with different types of HER2+ cancer that has spread and cannot be removed by surgery. People can take part in this study if...

Sponsor: Boehringer IngelheimEnrolling: 76820 locations
RECRUITINGNCT05642338

A Multicenter Prospective Cohort Study Comparing Random Biopsies Versus Wide-Area Transepithelial Brush-Sampling (WATS)...

The investigators aim to study the rate of developing a biopsy-based diagnosis of high-grade dysplasia (HGD) and EAC in BE patients in a prospective cohort of 208 BE patients at...

Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)Enrolling: 4161 location
RECRUITINGPhase 1NCT06623396

A Study of Mesothelin-Targeted CAR T-Cell Therapy in People With Esophagogastric Cancer

Participants will have a sample of their white blood cells, called T cells, collected using a procedure called leukapheresis. The collected T cells will be sent to a laboratory at...

Sponsor: Memorial Sloan Kettering Cancer CenterEnrolling: 187 locations
RECRUITINGPhase 2NCT04939051

Obeticholic Acid for Prevention in Barrett's Esophagus

This phase II trial studies the effect of obeticholic acid in treating patients with Barrett's esophagus. Bile acids present in duodenogastroesophageal reflux contribute to...

Sponsor: National Cancer Institute (NCI)Enrolling: 308 locations
RECRUITINGNCT06523374

A Study of Barrett's Esophagus Patients to Investigate Quality of Life and Fear of Cancer, and Optimize a Risk Model...

This study serves, in part, to prepare for a future large cohort study. The goal of the study is: 1. The collection of various tissue samples (blood, biopsies and "esophageal...

Sponsor: University Hospital, AntwerpEnrolling: 509 locations
RECRUITINGPhase 1NCT07182149

A Phase 1 Study of NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid Tumors

This study is being done to find out of NRM-823 is safe and can treat participants with locally advanced or metastatic solid tumors.

Sponsor: Normunity AccelCo, Inc.Enrolling: 1509 locations
RECRUITINGNCT04290806

Registry Platform Gastric/Esophageal Cancer (SAPHIR)

The registry aims to collect and analyse information on the antineoplastic treatment of patients with metastatic esophageal, gastric or gastroesophageal junction cancer, treated...

Sponsor: iOMEDICO AGEnrolling: 19001 location
RECRUITINGPhase 1NCT07021066

Evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of BL-M05D1 in Subjects With Solid Tumors

The objective of this study is to evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of BL-M05D1 in Subjects with Advanced or Metastatic Solid Tumors.

Sponsor: SystImmune Inc.Enrolling: 16017 locations

Frequently Asked Questions

There are currently 11 clinical trials for Esophageal Adenocarcinoma, with 11 actively recruiting participants. These include trials across all phases from early-stage Phase 1 to late-stage Phase 3.

To join a clinical trial for Esophageal Adenocarcinoma, review the eligibility criteria on the trial detail pages, then talk to your doctor about whether a trial is right for you. Your doctor can help you evaluate the potential benefits and risks.

Phase 3 trials are large-scale studies that test whether a treatment is effective and monitor side effects. There are 0 Phase 3 trials for Esophageal Adenocarcinoma, representing treatments closest to potential FDA approval.

Clinical trials follow strict safety protocols overseen by Institutional Review Boards (IRBs) and the FDA. Participants are monitored closely and can withdraw at any time. Always discuss risks and benefits with your healthcare provider before enrolling.

Sources: ClinicalTrials.gov, FDA
Last updated:

Trial data sourced from the ClinicalTrials.gov API. This site does not provide medical advice, always talk to your doctor about clinical trial participation.