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AbbVie

30 clinical trials · 30 recruiting · INDUSTRY

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.

Trials by AbbVie

RECRUITINGPhase 1NCT05005403

Study to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer, Head and...

Cancer is a condition where cells in a specific part of body grow and reproduce uncontrollably. Non-Small Cell Lung Cancer (NSCLC) is a solid tumor, a disease in which cancer...

Sponsor: AbbVieEnrolling: 69420 locations
Non-Small Cell Lung CancerHead and Neck Squamous Cell CarcinomaMicro Satellite Stable Colorectal Cancer+4
RECRUITINGPhase 2NCT07059845

A Study to Assess Adverse Events and Change in Disease Activity of Multiple Treatment Combinations With Intravenous...

Ovarian cancer is a lethal disease with an estimated 310,000 new cases and 200,000 deaths experienced worldwide in 2020. The purpose of this study is to assess the adverse events...

Sponsor: AbbVieEnrolling: 32010 locations
Ovarian Cancer
RECRUITINGPhase 1 / Phase 2NCT06892522

A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Multiple Myeloma...

Multiple myeloma (MM) is a cancer of the blood's plasma cells. The cancer is typically found in the bones and bone marrow (the spongy tissue inside of the bones) and can cause...

Sponsor: AbbVieEnrolling: 44020 locations
Multiple Myeloma
RECRUITINGPhase 1NCT07409246

A Study to Evaluate Adverse Events, Change in Disease Activity, Tolerability, and How Intravenous ABBV-438 Moves...

Multiple myeloma (MM) is a plasma cell disease characterized by the growth of clonal plasma cells in the bone marrow. The purpose of this study is to assess the safety,...

Sponsor: AbbVieEnrolling: 1271 location
Multiple Myeloma
RECRUITINGNCT06916507

Study to Assess Real Life Effectiveness of Foslevodopa/Foscarbidopa in Adult German Participants at Initial Stages of...

Parkinson's disease (PD) is a neurological condition, which affects the brain. PD gets worse over time, but how quickly it progresses varies a lot from person to person. Some...

Sponsor: AbbVieEnrolling: 12513 locations
Parkinson's Disease
RECRUITINGNCT06965374

Real-World Study of Foslevodopa/Foscarbidopa to Assess Quality of Life Outcomes in Adult Participants With Advanced...

Parkinson's disease (PD) is a neurological condition, which affects the brain. PD gets worse over time, but how quickly it progresses varies a lot from person to person. Some...

Sponsor: AbbVieEnrolling: 27019 locations
Parkinson Disease
RECRUITINGPhase 3NCT06806293

Study of Oral Atogepant to Assess Adverse Events and Change in Disease Activity in Adult Participants With Menstrual...

A migraine attack is a moderate or severe headache that usually occurs on one side of the head and is often throbbing or pulsating. The headache is often accompanied by...

Sponsor: AbbVieEnrolling: 43020 locations
Menstrual Migraine (MM)
RECRUITINGPhase 3NCT06810505

A Study of Oral Atogepant Tablets to Assess Adverse Events and Change in Disease Activity To Prevent Migraine in...

Migraine is a disease that most often causes moderate to severe headache on one side of the head. A migraine attack is a headache that may be accompanied by throbbing, nausea,...

Sponsor: AbbVieEnrolling: 42020 locations
Chronic Migraine
RECRUITINGPhase 2NCT06602479

A Study to Investigate the Safety and Efficacy of MEDI0618 Compared to Placebo in Adult Participants With Episodic...

The purpose of this Phase 2 study is to evaluate the safety and efficacy of SC MEDI0618 compared to placebo in participants with episodic migraine.

Sponsor: AbbVieEnrolling: 48820 locations
Migraine
RECRUITINGNCT06603558

Post-Marketing Study to Assess the Safety and Effectiveness of Oral Atogepant in Korean Adult Participants for the...

Migraine is a neurological disease characterized by moderate or severe headache, associated with nausea, vomiting, and/or sensitivity to light and sound. The study will assess the...

Sponsor: AbbVieEnrolling: 30004 locations
Chronic MigraineEpisodic MigraineMigraine
RECRUITINGNCT07310290

Study to Assess the Real-World Effectiveness of Ubrogepant in Adult Participants When Treating During the Prodrome...

Migraine is a neurological disease characterized by moderate or severe headaches, associated with nausea, vomiting, and/or sensitivity to light and sound. This study will assess...

Sponsor: AbbVieEnrolling: 1893 locations
Migraine
RECRUITINGPhase 2NCT06846320

Study to Assess Adverse Events and Change in Disease Activity When Oral ABBV-932 is Added to Antidepressant Therapies...

Generalized anxiety disorder (GAD) is usually treated with antidepressant therapy (ADT); however, sometimes ADTs alone are not enough to adequately treat GAD. The purpose of this...

Sponsor: AbbVieEnrolling: 31520 locations
Generalized Anxiety Disorder (GAD)
RECRUITINGPhase 3NCT04777357

A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive...

Bipolar disorder is a severe chronic mood disorder that affects up to 4% of the adult population and 1.8% of the pediatric population in the United States. The treatment of the...

Sponsor: AbbVieEnrolling: 38020 locations
DepressionBipolar I Disorder
RECRUITINGNCT06712628

A Comparison Study of Persistence of UPadacitinib vs. TNF-inhibitoRs In a German Real-world SettING

This study will compare the retention rates for UPA vs. TNFi treatment in adult participants with moderate to severe active RA per local label and according to local standard of...

Sponsor: AbbVieEnrolling: 67820 locations
Moderate to Severe Rheumatoid Arthritis
RECRUITINGPhase 3NCT05843643

Program to Assess Adverse Events and Change in Disease Activity of Oral Upadacitinib in Adult Participants With...

Systemic Lupus Erythematosus (SLE) is an immune-mediated disease associated with inflammation of multiple organ systems. This study will assess how safe and effective upadacitinib...

Sponsor: AbbVieEnrolling: 100020 locations
Systemic Lupus Erythematosus
RECRUITINGNCT06581042

Study to Assess Treatment Patterns and Outcomes With Upadacitinib in Adult Participants With Inflammatory Bowel Disease...

Crohn's disease (CD) is an incurable chronic inflammatory disorder of the gastrointestinal tract. Ulcerative colitis (UC) is an idiopathic, chronic, inflammatory disease affecting...

Sponsor: AbbVieEnrolling: 2807 locations
Ulcerative ColitisCrohn's Disease
RECRUITINGNCT07421258

A Retrospective Study to Evaluate Treat-to-Target and Disease Modification in Adult Participants With Crohn's Disease...

Inflammatory Bowel Disease (IBD), encompassing Crohn's Disease (CD) and Ulcerative Colitis (UC), is a chronic, relapsing, and often disabling condition characterized by...

Sponsor: AbbVieEnrolling: 20004 locations
Crohn's DiseaseUlcerative Colitis
RECRUITINGNCT06764706

Study to Assess Change in Disease Activity of Risankizumab Treatment in Adult Participants With Moderate to Severe...

Ulcerative colitis (UC) is a type of inflammatory bowel disease that causes inflammation and bleeding from the lining of the rectum and colon (large intestine). This study will...

Sponsor: AbbVieEnrolling: 20020 locations
Ulcerative Colitis
RECRUITINGNCT05496348

Study of Oral Upadacitinib to Assess Change in Disease Activity in Adult Participants With Ulcerative Colitis

Ulcerative colitis (UC) is a type of inflammatory bowel disease that causes inflammation and bleeding from the lining of the rectum and colon (large intestine).This study will...

Sponsor: AbbVieEnrolling: 40020 locations
Ulcerative Colitis
RECRUITINGNCT07136116

Study to Assess Change in Disease Activity of Risankizumab Treatment in Japanese Participants With Moderate to Severe...

Ulcerative colitis (UC) is a type of inflammatory bowel disease that causes inflammation and bleeding from the lining of the rectum and colon (large intestine). This study will...

Sponsor: AbbVieEnrolling: 20020 locations
Ulcerative Colitis
RECRUITINGPhase 2NCT06865105

Study of Targeted Therapies for the Treatment of Adult Participants With Active Psoriatic Arthritis

Psoriatic arthritis (PsA) is a type of arthritis that happens when the body's immune system attacks healthy cells and tissues causing joint pain, stiffness, and swelling. Symptoms...

Sponsor: AbbVieEnrolling: 12020 locations
Psoriatic Arthritis
RECRUITINGPhase 3NCT06100744

A Study to Assess Adverse Events, Change in Disease Activity, and How the Drug Moves Through the Body in Children With...

Psoriatic arthritis (PsA) is a type of arthritis that happens when the body's immune system attacks healthy cells and tissues causing joint pain, stiffness, and swelling. Symptoms...

Sponsor: AbbVieEnrolling: 4020 locations
Juvenile Psoriatic Arthritis
RECRUITINGNCT07039110

Study to Assess Change in Quality of Life of Risankizumab Treatment in Adult Participants With Moderate-to-Severe...

Psoriasis is a chronic, systemic, inflammatory disease in which skin cells build up and develop thick, red and white scaly patches on the skin. This study will assess the change...

Sponsor: AbbVieEnrolling: 70020 locations
Plaque Psoriasis
RECRUITINGPhase 2 / Phase 3NCT06345339

A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary...

This study will evaluate the efficacy and safety of Armour Thyroid treatment compared with synthetic T4 in subjects who have primary hypothyroidism and are currently stabilized...

Sponsor: AbbVieEnrolling: 280020 locations
Hypothyroidism
RECRUITINGPhase 2NCT07230288

Study of ABBV-142 to Assess Adverse Events and Change in Disease Activity in Adult Participants With Idiopathic...

Idiopathic Pulmonary Fibrosis (IPF) is a rare, long-lasting lung disease that causes scarring of lung tissue, shortness of breath, and loss of lung function. IPF leads to...

Sponsor: AbbVieEnrolling: 1654 locations
Idiopathic Pulmonary Fibrosis
RECRUITINGNCT07419347

Study of Glecaprevir/Pibrentasvir to Assess Safety Through Real-World Data

The objective of this study is to assess the safety, tolerability and effectiveness of 8-week Glecaprevir/Pibrentasvir (G/P) in participants taking either prescribed or illicit...

Sponsor: AbbVieEnrolling: 20002 locations
Hepatitis C Virus (HCV)
RECRUITINGPhase 3NCT05407636

Pivotal 2 Study of RGX-314 Gene Therapy in Participants With nAMD

ABBV-RGX-314 (also known as RGX-314) is being developed as a novel one-time gene therapy for the treatment of neovascular (wet) age-related macular degeneration (wet AMD). Wet AMD...

Sponsor: AbbVieEnrolling: 66020 locations
AMDnAMDWet Age-related Macular Degeneration+3
RECRUITINGPhase 1 / Phase 2NCT07160179

Study to Assess the Adverse Events and How Intravitreal ABBV-6628 Moves Through the Body of Adult Participants With...

Age-related macular degeneration (AMD) is the abnormal growth of new blood vessels in the light-sensitive tissue at the back of the eye called the retina. Geographic Atrophy (GA)...

Sponsor: AbbVieEnrolling: 664 locations
Geographic AtrophyAge-Related Macular Degeneration
RECRUITINGPhase 1 / Phase 2NCT04499248

AGN-193408 SR in the Treatment of Open-angle Glaucoma or Ocular Hypertension

This is a multicenter, open-label, dose escalation (Cohort 1) to masked, randomized, parallel-groups (Cohort 2) and (Cohort 3) study to evaluate the safety and efficacy of...

Sponsor: AbbVieEnrolling: 9620 locations
Open-angle GlaucomaOcular Hypertension
RECRUITINGPhase 3NCT06822738

A Study to Assess Adverse Events and Effectiveness of Gel Stent (XEN63) Implantation Using Ab Interno and Ab Externo...

Glaucoma is the second most common cause of blindness in the world, second only to cataracts. This study will assess how safe and effective a glaucoma gel stent is when implanted...

Sponsor: AbbVieEnrolling: 13020 locations
Primary Open Angle Glaucoma