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Clinical Trials in Delaware

38 recruiting clinical trials across 5 cities in Delaware (DE). Eligibility criteria explained in plain English.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
38
Total Trials
38
Recruiting Now
5
Cities
20
Conditions

Recruiting Trials in Delaware

Clinical trial data sourced from ClinicalTrials.gov. Always consult your doctor before considering any clinical trial.

RECRUITINGNCT02135705

LOWER: Lomitapide Observational Worldwide Evaluation Registry

This global product exposure registry is a multicentre, long-term, prospective, observational cohort study (exposure registry), designed to evaluate the long term safety and...

Sponsor: Amryt PharmaEnrolling: 30020 locations
Homozygous Familial Hypercholesterolemia
RECRUITINGPhase 1 / Phase 2NCT03128996

Reduced Intensity Conditioning and Familial HLA-Mismatched BMT for Non-Malignant Disorders

This study is designed to estimate the efficacy and toxicity of familial HLA mismatched bone marrow transplants in patients with non-malignant disease who are less than 21 years...

Sponsor: Washington University School of MedicineEnrolling: 294 locations
Severe Sickle Cell DiseaseBone Marrow Failure SyndromesMetabolic Disorders+3
RECRUITINGPhase 3NCT03401398

Stress Hydrocortisone In Pediatric Septic Shock

SHIPSS is a multi-institutional, prospective, controlled, randomized, double-blinded interventional trial that will examine the potential benefits and risks of adjunctive...

Sponsor: Jerry ZimmermanEnrolling: 50020 locations
Septic Shock
RECRUITINGNCT03452774

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

International registry for cancer patients evaluating the feasibility and clinical utility of an Artificial Intelligence-based precision oncology clinical trial matching tool,...

Sponsor: Massive Bio, Inc.Enrolling: 5000020 locations
Cancer, MetastaticCancerCancer of Pancreas+40
RECRUITINGPhase 2NCT04015141

A Study to Evaluate Efficacy and Safety of Perampanel Administered as an Adjunctive Therapy in Pediatric Participants...

The purpose of the study is to evaluate the efficacy of perampanel as measured by the 50 percent (%) responder rate during the maintenance period of the core study for seizure...

Sponsor: Eisai Inc.Enrolling: 10020 locations
Pediatric Epileptic SyndromePartial-onset Seizures
RECRUITINGNCT04278404

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of...

The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults...

Sponsor: Duke UniversityEnrolling: 500020 locations
Coronavirus Infection (COVID-19)Pulmonary Arterial HypertensionUrinary Tract Infections in Children+22
RECRUITINGNCT04398628

ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

In parallel with the growth of ATHN's clinical studies, the number of new therapies for all blood disorders is increasing significantly. Some of the recently FDA-approved...

Sponsor: American Thrombosis and Hemostasis NetworkEnrolling: 300020 locations
Hematologic DisorderBleeding DisorderConnective Tissue Disorder+10
RECRUITINGPhase 1NCT04617522

Study of Sacituzumab Govitecan in Participants With Advanced or Metastatic Solid Tumor and Moderate Liver Impairment

The goals of this clinical study are to learn more about the safety and dosing of the study drug, sacituzumab govitecan-hziy, in participants with solid tumors and moderate liver...

Sponsor: Gilead SciencesEnrolling: 3013 locations
Advanced or Metastatic Solid TumorLiver Failure
RECRUITINGPhase 3NCT04829539

Comparing Brief Behavioral Therapy (BBT-CI) and Healthy Eating Education Learning (HEAL) for Cancer-Related Sleep...

This phase III trial compares BBT-CI to HEAL for the reduction of insomnia in patients with stage I-IV cancer who are receiving cancer treatment. Cancer treatment can cause side...

Sponsor: University of Rochester NCORP Research BaseEnrolling: 40020 locations
Hematopoietic and Lymphoid Cell NeoplasmMalignant Solid Neoplasm
RECRUITINGNCT05112237

Natural History Study in Pediatric Patients With MYBPC3 Mutation-associated Cardiomyopathy

The objective of this study is to collect information on patients with cardiomyopathy (CM) due to mutations in the MYBPC3 gene, to evaluate their disease course, burden of...

Sponsor: Tenaya TherapeuticsEnrolling: 20020 locations
Cardiomyopathy
RECRUITINGPhase 2NCT05283720

A Study to Evaluate Adverse Events and Change in Disease Activity of Subcutaneous (SC) Epcoritamab in Combination With...

B-cell Lymphoma is an aggressive and rare cancer of a type of immune cell (a white blood cell responsible for fighting infections). The purpose of this study is to assess the...

Sponsor: GenmabEnrolling: 49620 locations
Non-Hodgkin Lymphoma
RECRUITINGNCT05383911

Empowering Adolescents and Young Adults With Sickle Cell Disease as Partners in Treatment Decision Making (EMPOWER-AYA)

This study will evaluate the acceptability, feasibility, and preliminary efficacy of a shared decision making intervention for adolescents and young adults (AYAs) with sickle cell...

Sponsor: Nemours Children's ClinicEnrolling: 681 location
Sickle Cell Disease
RECRUITINGPhase 2NCT05647265

Testing the Addition of Immunotherapy Before Surgery for Patients With Sarcomatoid Mesothelioma

This phase II trial evaluates the safety and effectiveness of giving immunotherapy (nivolumab and ipilimumab) before surgery for controlling disease in patients with stage I-IIIa...

Sponsor: Alliance for Clinical Trials in OncologyEnrolling: 2620 locations
Pleural Biphasic MesotheliomaPleural Sarcomatoid Mesothelioma
RECRUITINGNCT05889624

Responding With Evidence and Access for Childhood Headaches

This comparative effectiveness study will clarify current first-line preventive treatment approaches for use by neurologists, psychologists, and primary care providers in the...

Sponsor: Children's Hospital Medical Center, CincinnatiEnrolling: 40015 locations
HeadacheHeadache DisordersHeadache, Migraine+5
RECRUITINGPhase 2NCT05948566

Strategy for Improving Stroke Treatment Response

SISTER is a Phase-II, prospective, randomized, placebo-controlled, blinded, dose finding trial that aims to determine the safety and preliminary efficacy of TS23, a monoclonal...

Sponsor: Translational Sciences, Inc.Enrolling: 30020 locations
Ischemic Stroke
RECRUITINGPhase 2NCT06064097

A Study Using Nivolumab, in Combination With Chemotherapy Drugs to Treat Nasopharyngeal Carcinoma (NPC)

This phase II trial tests effects of nivolumab in combination with chemotherapy drugs prior to radiation therapy patients with nasopharyngeal carcinoma (NPC). Immunotherapy with...

Sponsor: National Cancer Institute (nci)Enrolling: 5020 locations
Stage II Nasopharyngeal Carcinoma AJCC v8Stage III Nasopharyngeal Carcinoma AJCC v8Stage IV Nasopharyngeal Carcinoma AJCC v8
RECRUITINGNCT06071377

Achieving Understanding of the Natural History of Sickle Cell Trait (AUNT)

The main purpose of this study is to create a longitudinal cohort of those with Sickle Cell Trait (SCT) to better understand the hematologic phenotype for those that carry HbS,...

Sponsor: National Alliance for Sickle Cell CentersEnrolling: 100010 locations
Sickle Cell Trait
RECRUITINGNCT06093906

Positive Processes and Transition to Health (PATH)

The R33 will be a randomized controlled trial to replicate changes in the targets (unproductive processing, avoidance, reward deficits) from the R61 phase in a larger sample of...

Sponsor: Case Western Reserve UniversityEnrolling: 1353 locations
Posttraumatic Stress DisorderMajor Depressive Disorder
RECRUITINGPhase 2 / Phase 3NCT06225596

Study BT8009-230 in Participants With Locally Advanced or Metastatic Urothelial Cancer (Duravelo-2)

This is a global, multicenter, randomized, open-label study, with an adaptive design. The main objective of the study is to measure the efficacy and safety of BT8009 (zelenectide...

Sponsor: BicycleTx LimitedEnrolling: 95620 locations
Metastatic Urothelial Cancer
RECRUITINGPhase 3NCT06238622

A Follow-up Study to Test Long-term Treatment With Nerandomilast in People With Pulmonary Fibrosis Who Took Part in a...

This study is open to people with idiopathic pulmonary fibrosis (IPF) or progressive pulmonary fibrosis (PPF). They can only take part if they have completed treatment in a...

Sponsor: Boehringer IngelheimEnrolling: 170020 locations
Idiopathic Pulmonary FibrosisProgressive Pulmonary Fibrosis
RECRUITINGPhase 2NCT06290401

A Socio-ecological Approach for Improving Self-management in Adolescents With SCD

The goal of this clinical trial is to evaluate the impact of SCThrive (a behavioral self-management intervention) on patient activation, self-management behaviors, daily...

Sponsor: Children's Hospital Medical Center, CincinnatiEnrolling: 3104 locations
Anemia, Sickle Cell
RECRUITINGPhase 3NCT06307665

Evaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As Needed in Participants 12 to < 18 Years...

The purpose of this study is to compare the effect of budesonide/albuterol metered-dose inhaler (BDA MDI) with albuterol sulfate metered-dose inhaler (AS MDI), both administered...

Sponsor: AstraZenecaEnrolling: 44020 locations
Asthma
RECRUITINGNCT06368648

CoMind Early Feasibility Study

The purpose of this research, which has been determined as non-significant risk by the central IRB overseeing the study, is to obtain information to help further develop a machine...

Sponsor: CoMind Technologies LimitedEnrolling: 58114 locations
Intracranial PressureIntracranial Pressure ChangesTraumatic Brain Injury+6
RECRUITINGPhase 3NCT06401330

A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)

This phase III trial studies using risk factors in determining treatment for children with favorable tissue (histology) Wilms tumors (FHWT). Wilms Tumor is the most common type of...

Sponsor: Children's Oncology GroupEnrolling: 165620 locations
Stage I Mixed Cell Type Kidney Wilms TumorStage II Mixed Cell Type Kidney Wilms TumorStage III Mixed Cell Type Kidney Wilms Tumor+1
RECRUITINGNCT06433752

A Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing...

The purpose of this study is to evaluate safety, effiectiveness, and to gain insight into the treatment experience of participants prescribed BRIUMVI® (ublituximab-xiiy) in the...

Sponsor: TG Therapeutics, Inc.Enrolling: 50020 locations
Relapsing Multiple SclerosisMultiple Sclerosis
RECRUITINGNCT06458985

Disclosure Intervention for People in Treatment for Opioid Use Disorder

The goal of this clinical trial is to test a disclosure intervention among people in treatment for opioid use disorder. The main question it aims to answer is whether people who...

Sponsor: University of DelawareEnrolling: 4801 location
Opioid Use Disorder
RECRUITINGPhase 3NCT06470243

Testing Whether the Addition of Carboplatin Chemotherapy to Cabazitaxel Chemotherapy Will Improve Outcomes Compared to...

This phase III trial compares the effect of adding carboplatin to the standard of care chemotherapy drug cabazitaxel versus cabazitaxel alone in treating prostate cancer that...

Sponsor: SWOG Cancer Research NetworkEnrolling: 52820 locations
Castration-Resistant Prostate CarcinomaStage IVB Prostate Cancer AJCC v8
RECRUITINGNCT06492733

FastWire REvascularisation of Extremities, (For LOWer Limbs) - FREEFLOW

This study is to assess the safety and efficacy of the FastWire System. It is intended to assess that the FastWire System can facilitate the intra-luminal placement of...

Sponsor: Versono Medical LtdEnrolling: 656 locations
Chronic Total Occlusion of Artery of the Extremities
RECRUITINGPhase 3NCT06612268

A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Disease

This study is conducted to confirm whether etavopivat works well at reducing the number of Vaso-occlusive crisis VOCs (sickle cell pain crises) caused by obstructions in blood...

Sponsor: Novo Nordisk A/SEnrolling: 40820 locations
Sickle Cell Disease
RECRUITINGNCT06643741

Non-Invasive Preeclampsia Screening and Biobank

Women pregnant between 11-14 weeks gestation will be enrolled with blood samples collected to evaluate for preeclampsia.

Sponsor: Sequenom, INC.Enrolling: 655020 locations
Preeclampsia (PE)

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Frequently Asked Questions

There are currently 38 clinical trials actively recruiting participants in Delaware. These span all phases from early-stage Phase 1 to late-stage Phase 3 trials, across 20+ conditions.

The top conditions with recruiting trials in Delaware include Sickle Cell Disease, Hemophilia, Homozygous Familial Hypercholesterolemia, Severe Sickle Cell Disease, Bone Marrow Failure Syndromes. Each has multiple active trials across research centers in the state.

Major trial sites in Delaware include Wilmington, Newark, Millville, Rehoboth Beach, Lewes. Most large academic medical centers and research hospitals serve as trial sites.

Review the trial listings on this page and check the eligibility criteria — we translate them into plain English. When you find a trial that fits, talk to your doctor about whether it's right for you, then contact the trial team directly using the information on the trial page.

Sources: ClinicalTrials.gov
Last updated:

Trial data sourced from the ClinicalTrials.gov API. Location data reflects registered trial sites. This site does not provide medical advice.