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Clinical Trials in Virginia

243 recruiting clinical trials across 15 cities in Virginia (VA). Eligibility criteria explained in plain English.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
243
Total Trials
243
Recruiting Now
15
Cities
20
Conditions

Recruiting Trials in Virginia

Clinical trial data sourced from ClinicalTrials.gov. Always consult your doctor before considering any clinical trial.

RECRUITINGNCT00567073

Pompe Pregnancy Sub-Registry

This Sub-registry is a multicenter, international, longitudinal, observational, and voluntary program designed to track pregnancy outcomes for any pregnant woman enrolled in the...

Sponsor: Genzyme, a Sanofi CompanyEnrolling: 2020 locations
Glycogen Storage Disease Type II (GSD-II)Pompe Disease (Late-onset)Glycogenesis 2 Acid Maltase Deficiency
RECRUITINGNCT00733590

Prospective Observational Study of the ICD in Sudden Cardiac Death Prevention

The overall hypothesis of this study is that subtle interactions between structural (substrate) and functional (trigger) abnormalities of the heart, some of which are...

Sponsor: Johns Hopkins UniversityEnrolling: 15004 locations
Heart Failure, CongestiveDeath, Sudden, CardiacArrhythmia+1
RECRUITINGNCT00756665

Prostate Active Surveillance Study

The Prostate Active Surveillance Study (PASS) is a research study for men who have chosen active surveillance as a management plan for their prostate cancer. Active surveillance...

Sponsor: University of WashingtonEnrolling: 300011 locations
Prostatic Neoplasms
RECRUITINGEarly Phase 1NCT00929006

Acute Progesterone Suppression of Wake vs. Sleep Luteinizing Hormone Pulse Frequency in Pubertal Girls With and Without...

The purpose of this study is two-fold. (1) We will determine if in mid- to late pubertal girls without hyperandrogenism (HA), progesterone (P4) acutely reduces waking luteinizing...

Sponsor: University of VirginiaEnrolling: 361 location
PubertyHyperandrogenism
RECRUITINGNCT00969111

Postoperative or Salvage Radiotherapy (RT) for Node Negative Prostate Cancer Following Radical Prostatectomy

The purpose of this study is to see what effects, good and/or bad, proton radiation, and/or conventional radiation and hormonal therapy (if applicable), has on prostate cancer...

Sponsor: Proton Collaborative GroupEnrolling: 704 locations
Prostate Cancer
RECRUITINGPhase 3NCT02670707

Vinblastine/Prednisone Versus Single Therapy With Cytarabine for Langerhans Cell Histiocytosis (LCH)

Langerhans Cell Histiocytosis (LCH) is a type of cancer that can damage tissue or cause lesions to form in one or more places in the body. Langerhans cell histiocytosis (LCH) is a...

Sponsor: Baylor College of MedicineEnrolling: 12411 locations
Langerhans Cell Histiocytosis
RECRUITINGNCT02995252

The HOPE Study: Characterizing Patients With Hepatitis B and C

This is an observational, longitudinal, prospective study for sample collection and evaluation for future therapy or disease progression of chronic hepatitis B and C. Participants...

Sponsor: University of Maryland, BaltimoreEnrolling: 5502 locations
Hepatitis B, ChronicHepatitis C
RECRUITINGNCT03004326

Clinical Transcriptomics in Systemic Vasculitis (CUTIS)

Multi-center observational study to evaluate the histopathology and transcriptome of cutaneous lesions in patients with several different types of vasculitis.

Sponsor: Peter MerkelEnrolling: 5010 locations
Cryoglobulinemic Vasculitis (CV)Drug-induced VasculitisEosinophilic Granulomatosis With Polyangiitis (EGPA)+7
RECRUITINGPhase 3NCT03127267

Efficacy and Safety of Masitinib Versus Placebo in the Treatment of ALS Patients

The objective is to compare the efficacy and safety of masitinib in combination with riluzole versus matched placebo in combination with riluzole for the treatment of Amyotrophic...

Sponsor: Ab ScienceEnrolling: 49520 locations
Amyotrophic Lateral Sclerosis
RECRUITINGPhase 1 / Phase 2NCT03331302

Hyper Polarized Xenon-129 MRI vs Xenon-133 Scintigraphy

Hyper polarized Xenon-129 MRI will be directly compared to a radioactive Xe-133 scintigraphy to detect defects in lung ventilation from airflow limitation. This study is conducted...

Sponsor: University of VirginiaEnrolling: 301 location
Chronic Obstructive Pulmonary Disease
RECRUITINGPhase 2 / Phase 3NCT03373968

Givinostat in Duchenne's Muscular Dystrophy Long-term Safety and Tolerability Study

This is an open label, long-term safety, tolerability, and efficacy study of GIVINOSTAT in all DMD (Duchenne's muscular dystrophy) patients who have been previously treated in one...

Sponsor: ItalfarmacoEnrolling: 20620 locations
Duchenne Muscular Dystrophy
RECRUITINGNCT03378739

Inova Cardiogenic Shock Registry (INOVA SHOCK)

To collect retrospective clinical outcomes related to acute decompensated heart failure cardiogenic shock, acute myocardial infarction cardiogenic shock and compare current versus...

Sponsor: Inova Health Care ServicesEnrolling: 30001 location
Cardiogenic Shock
RECRUITINGPhase 3NCT03593759

Cardiac Sarcoidosis Randomized Trial

Prospective randomized controlled trial comparing low dose Prednisone(or Prednisolone)/Methotrexate combination to standard dose Prednisone(or Prednisolone) in patients diagnosed...

Sponsor: Ottawa Heart Institute Research CorporationEnrolling: 19420 locations
Cardiac SarcoidosisSarcoidosis
RECRUITINGEarly Phase 1NCT03905603

Relative Contributions of Predictors of Hyperandrogenism in Older vs. Young Women With PCOS

The objective of the study is to determine the relative contributions of four established predictors of hyperandrogenism (luteinizing hormone \[LH\] secretion, ovarian response to...

Sponsor: University of VirginiaEnrolling: 1441 location
Polycystic Ovary Syndrome
RECRUITINGNCT03995238

Optimizing Gait Rehabilitation for Veterans With Non-traumatic Lower Limb Amputation

The population of older Veterans with non-traumatic lower limb amputation is growing. Following lower limb amputation, asymmetrical movements persist during walking and likely...

Sponsor: VA Office of Research and DevelopmentEnrolling: 542 locations
Transtibial AmputationPeripheral Artery DiseaseDiabetes Mellitus
RECRUITINGPhase 2NCT04015141

A Study to Evaluate Efficacy and Safety of Perampanel Administered as an Adjunctive Therapy in Pediatric Participants...

The purpose of the study is to evaluate the efficacy of perampanel as measured by the 50 percent (%) responder rate during the maintenance period of the core study for seizure...

Sponsor: Eisai Inc.Enrolling: 10020 locations
Pediatric Epileptic SyndromePartial-onset Seizures
RECRUITINGPhase 3NCT04047628

Best Available Therapy Versus Autologous Hematopoietic Stem Cell Transplant for Multiple Sclerosis (BEAT-MS)

This is a multi-center prospective rater-masked (blinded) randomized controlled trial of 156 participants, comparing the treatment strategy of Autologous Hematopoietic Stem Cell...

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)Enrolling: 15620 locations
Relapsing Multiple SclerosisRelapsing Remitting Multiple SclerosisSecondary Progressive Multiple Sclerosis
RECRUITINGNCT04054310

Non-Invasive Quantification of Liver Health in NASH (N-QUAN)

To evaluate, in patients with suspected NASH referred for liver biopsy, the diagnostic performance of CT1 at discriminating those with NAS≥4 \& F≥2 from those without.

Sponsor: PerspectumEnrolling: 2257 locations
NASH - Nonalcoholic Steatohepatitis
RECRUITINGPhase 1 / Phase 2NCT04094610

A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations

Phase 1 will evaluate the safety and tolerability at different dose levels of repotrectinib in pediatric and young adult subjects with advanced or metastatic malignancies...

Sponsor: Turning Point Therapeutics, Inc.Enrolling: 7520 locations
Locally Advanced Solid TumorsMetastatic Solid TumorsLymphoma+1
RECRUITINGPhase 1 / Phase 2NCT04104776

A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas

The purpose of this open-label, first-in-human (FIH) trial is to evaluate the safety, tolerability, and preliminary clinical activity of Tulmimetostat as a monotherapy in patients...

Sponsor: Novartis PharmaceuticalsEnrolling: 27520 locations
Advanced Solid TumorDiffuse Large B Cell LymphomaLymphoma, T-Cell+5
RECRUITINGPhase 2NCT04305769

Alanyl-glutamine Supplementation for C. Difficile Treatment (ACT)

This is a randomized, double-blind, placebo-controlled trial to determine the optimal dose and safety of oral alanyl-glutamine between 4, 24, and 44 g doses administered for 10...

Sponsor: University of VirginiaEnrolling: 2602 locations
Clostridioides Difficile InfectionClostridium Difficile InfectionClostridium Difficile Diarrhea+1
RECRUITINGNCT04372108

A Study to Assess the Long-Term Safety of Ustekinumab Versus Other Biologics in Patients With Crohn's Disease and...

The purpose of this study is to estimate and compare the incidence of overall malignancy, serious infection, and opportunistic infections between new users of ustekinumab and new...

Sponsor: Janssen Scientific Affairs, LLCEnrolling: 10561 location
Crohn DiseaseColitis, Ulcerative
RECRUITINGPhase 4NCT04575844

Effects of Exercise and GLP-1 Agonism on Muscle Microvascular Perfusion and Insulin Action in Adults With Metabolic...

The primary objective of this study is to examine whether exercise training alone, liraglutide treatment alone or exercise training plus liraglutide treatment increases cardiac...

Sponsor: University of VirginiaEnrolling: 801 location
Metabolic Syndrome
RECRUITINGNCT04592445

Endovascular Ablation of the Right Greater Splanchnic Nerve in Subjects Having HFpEF

The purpose of this clinical study is to evaluate the safety and early effectiveness of a catheter-based procedure that treats a nerve called the right greater splanchnic nerve....

Sponsor: Axon Therapies, INC.Enrolling: 15020 locations
Heart Failure With Preserved Ejection Fraction (HFpEF
RECRUITINGNCT04593082

Obesity and Pediatric Multiple Sclerosis

Obesity is one possible contributor to severity of multiple sclerosis and progression of the disease. We already know that obesity is a risk determinant for acquiring MS, yet the...

Sponsor: University of VirginiaEnrolling: 1162 locations
Multiple Sclerosis
RECRUITINGPhase 2NCT04606914

Study of Carboplatin and Mirvetuximab Soravtansine in First-Line Treatment of Patients Receiving Neoadjuvant...

The proposed study design is a single arm Phase II trial to document the feasibility of carboplatin-mirvetuximab - in patients with advanced-stage EOC. Patients with biopsy...

Sponsor: University of Alabama at BirminghamEnrolling: 709 locations
Ovarian CancerFallopian TubePrimary Peritoneal Cancer
RECRUITINGPhase 1NCT04626674

A Gene Transfer Therapy Study to Evaluate the Safety of and Expression From Delandistrogene Moxeparvovec (SRP-9001) in...

This is an open-label gene transfer therapy study evaluating the safety of and expression from delandistrogene moxeparvovec in participants with DMD. The maximum participant...

Sponsor: Sarepta Therapeutics, Inc.Enrolling: 837 locations
Muscular Dystrophy, Duchenne
RECRUITINGNCT04656496

NOURISH-T+: Promoting Healthy Eating and Exercise Behaviors

Pediatric cancer survivors are at an increased risk of excessive weight gain and reduced exercise behaviors with the potential for this risk to worsen over time. With over 80% of...

Sponsor: University of South FloridaEnrolling: 52010 locations
Obesity, ChildhoodCancerSurvivorship
RECRUITINGPhase 1 / Phase 2NCT04665206

Study to Evaluate VT3989 in Patients With Metastatic Solid Tumors

This is an open-label, dose escalation and expansion study to evaluate the safety, tolerability, PK, and biological activity of VT3989 administered, alone or in combination, once...

Sponsor: Vivace Therapeutics, IncEnrolling: 43412 locations
Solid Tumor, AdultMesotheliomaNSCLC
RECRUITINGNCT04682483

Cardiogenic Shock Working Group Registry

The Cardiogenic Shock Working Group is a multicenter registry where we collect de-identified clinical variables from the medical records and follow-up phone calls of shock...

Sponsor: Tufts Medical CenterEnrolling: 500016 locations
Cardiogenic Shock

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Frequently Asked Questions

There are currently 243 clinical trials actively recruiting participants in Virginia. These span all phases from early-stage Phase 1 to late-stage Phase 3 trials, across 20+ conditions.

The top conditions with recruiting trials in Virginia include Duchenne Muscular Dystrophy, Ovarian Cancer, Endometrial Cancer, NSCLC, Fabry Disease. Each has multiple active trials across research centers in the state.

Major trial sites in Virginia include Richmond, Charlottesville, Fairfax, Norfolk, Falls Church. Most large academic medical centers and research hospitals serve as trial sites.

Review the trial listings on this page and check the eligibility criteria — we translate them into plain English. When you find a trial that fits, talk to your doctor about whether it's right for you, then contact the trial team directly using the information on the trial page.

Sources: ClinicalTrials.gov
Last updated:

Trial data sourced from the ClinicalTrials.gov API. Location data reflects registered trial sites. This site does not provide medical advice.