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Clinical Trials in Ohio

521 recruiting clinical trials across 15 cities in Ohio (OH). Eligibility criteria explained in plain English.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
521
Total Trials
521
Recruiting Now
15
Cities
20
Conditions

Recruiting Trials in Ohio

Clinical trial data sourced from ClinicalTrials.gov. Always consult your doctor before considering any clinical trial.

RECRUITINGNCT00315380

Longitudinal Study for Eosinophilic Granulomatosis With Polyangiitis

Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare immune system disorder that causes asthma, an excessive number of eosinophils (a type of white blood cell) in the...

Sponsor: University of PennsylvaniaEnrolling: 70013 locations
Eosinophilic Granulomatosis With PolyangiitisChurg-Strauss Syndrome
RECRUITINGNCT00567073

Pompe Pregnancy Sub-Registry

This Sub-registry is a multicenter, international, longitudinal, observational, and voluntary program designed to track pregnancy outcomes for any pregnant woman enrolled in the...

Sponsor: Genzyme, a Sanofi CompanyEnrolling: 2020 locations
Glycogen Storage Disease Type II (GSD-II)Pompe Disease (Late-onset)Glycogenesis 2 Acid Maltase Deficiency
RECRUITINGNCT00682695

Genetic and Environmental Risk Factors for Hemorrhagic Stroke

The purpose of this study is to find risk factors for hemorrhagic stroke.

Sponsor: State University of New York at BuffaloEnrolling: 10007 locations
Stroke
RECRUITINGNCT01241305

One-Time DNA Study for Vasculitis

The purpose of this study is to identify genes that increase the risk of developing vasculitis, a group of severe diseases that feature inflammation of blood vessels. Results of...

Sponsor: University of PennsylvaniaEnrolling: 100014 locations
Eosinophilic Granulomatosis With Polyangiitis (Churg-Strauss)Giant Cell ArteritisGranulomatosis With Polyangiitis (Wegener's)+3
RECRUITINGNCT01401998

ARPKD Database Study

Hepato-renal fibrocystic diseases (HRFD) is a term developed that encompasses rare diseases such as Autosomal Recessive Polycystic Kidney Disease (ARPKD), and other diseases with...

Sponsor: Children's Hospital of PhiladelphiaEnrolling: 2006 locations
Hepato/Renal Fibrocystic DiseaseAutosomal Recessive Polycystic Kidney DiseaseJoubert Syndrome+7
RECRUITINGNCT01408225

Ohio State University Multiple Myeloma and Amyloidosis Data Registry and Sample Resource

The investigators are researching patients with diseases of their plasma cells in order to improve their quality and length of life. The investigators have created a database of...

Sponsor: Ohio State University Comprehensive Cancer CenterEnrolling: 50001 location
Plasma Cell DyscrasiasMonoclonal Gammopathy of Undetermined SignificanceAL Amyloidosis+1
RECRUITINGNCT01694940

North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)

The North American Mitochondrial Disease Consortium (NAMDC) maintains a patient contact registry and tissue biorepository for patients with mitochondrial disorders.

Sponsor: Columbia UniversityEnrolling: 100017 locations
Mitochondrial DisordersMitochondrial Genetic DisordersMitochondrial Diseases+2
RECRUITINGNCT01746537

Analysis of Anterior Chamber Inflammation by Optical Coherence Tomography

A prospective, observational, case series investigating the feasibility of utilizing OCT scans of the anterior chamber of eyes with uveitis.

Sponsor: The Cleveland ClinicEnrolling: 15001 location
Uveitis
RECRUITINGPhase 1 / Phase 2NCT01891318

Neoadjuvant Radiosurgery for Resectable Brain Metastases: Phase I/II Study

This Phase I/II trial studies the ability to stop brain metastases from coming back after treatment with radiosurgery followed by surgical resection. It will also evaluate the...

Sponsor: Case Comprehensive Cancer CenterEnrolling: 362 locations
Tumors Metastatic to Brain
RECRUITINGNCT01904851

Multi-Center Registry for Peripheral Arterial Disease Interventions and Outcomes

XLPAD is an observational study designed to evaluate the effectiveness and use of stent and non-stent based therapies among PAD patients. The study will create a registry that...

Sponsor: Baylor Research InstituteEnrolling: 1400020 locations
Peripheral Arterial Disease
RECRUITINGPhase 3NCT02000089

The Cancer of the Pancreas Screening-5 CAPS5)Study

Johns Hopkins clinical research office quality assurance group will monitor and audit this study at Johns Hopkins. The Sub Investigator at each site will be responsible for...

Sponsor: Johns Hopkins UniversityEnrolling: 90009 locations
Pancreas CancerPeutz-Jeghers Syndrome (PJS)Gene Mutation+2
RECRUITINGPhase 1 / Phase 2NCT02332668

A Study of Pembrolizumab (MK-3475) in Pediatric Participants With an Advanced Solid Tumor or Lymphoma...

Researchers are looking for new ways to treat children with different types of melanoma (skin cancer), solid tumors, and lymphomas (blood cancers) that are any of these: *...

Sponsor: Merck Sharp & Dohme LLCEnrolling: 37017 locations
MelanomaLymphomaSolid Tumor+2
RECRUITINGNCT02357238

Genetics of Uveitis

In order to improve the investigators knowledge about uveitis and the underlying mechanism of disease, the investigators propose collecting blood from patients with uveitis,...

Sponsor: The Cleveland ClinicEnrolling: 15001 location
UveitisInfectious Uveitis
RECRUITINGNCT02432560

Safety and Durability of Sirolimus for Treatment of LAM

The MIDAS study aims to follow male and female LAM patients who are currently taking, have previously failed or been intolerant of, or may (at some time in the future) take mTOR...

Sponsor: University of CincinnatiEnrolling: 60020 locations
Lymphangioleiomyomatosis
RECRUITINGPhase 3NCT02670707

Vinblastine/Prednisone Versus Single Therapy With Cytarabine for Langerhans Cell Histiocytosis (LCH)

Langerhans Cell Histiocytosis (LCH) is a type of cancer that can damage tissue or cause lesions to form in one or more places in the body. Langerhans cell histiocytosis (LCH) is a...

Sponsor: Baylor College of MedicineEnrolling: 12411 locations
Langerhans Cell Histiocytosis
RECRUITINGNCT02677961

An Electronic Health Record (EHR)-Based Comprehensive Bone and Soft Tissue Tumor Registry

Translational studies in cancer research can be impeded by the lack of high-quality clinical data that can be correlated with research questions. This is particularly true in the...

Sponsor: Ohio State University Comprehensive Cancer CenterEnrolling: 15001 location
Neoplasms, Connective and Soft TissueBone Neoplasms
RECRUITINGPhase 2 / Phase 3NCT02716246

Phase I/II/III Gene Transfer Clinical Trial of scAAV9.U1a.hSGSH

The main objective of this study is to evaluate the efficacy and safety of UX111 for the treatment of MPS IIIA.

Sponsor: Ultragenyx Pharmaceutical IncEnrolling: 365 locations
MPS IIIASanfilippo SyndromeSanfilippo A+1
RECRUITINGPhase 3NCT02735707

Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia

REMAP-CAP is a randomised, embedded, multifactorial, adaptive platform trial for community-acquired pneumonia. The purpose of this study is to evaluate the effect of a range of...

Sponsor: UMC UtrechtEnrolling: 2000020 locations
Community-acquired Pneumonia, Influenza, COVID-19
RECRUITINGNCT02780297

Prospective Research Rare Kidney Stones (ProRKS)

The purpose of this study is to determine the natural history of the hereditary forms of nephrolithiasis and chronic kidney disease (CKD), primary hyperoxaluria (PH), cystinuria,...

Sponsor: Mayo ClinicEnrolling: 22011 locations
HyperoxaluriaCystinuriaDent Disease+2
RECRUITINGNCT02824471

Sickle Cell Disease Biofluid Chip Technology (SCD BioChip)

'Sickle-shaped' anemia was first clinically described in the US in 1910, and the mutated heritable sickle hemoglobin molecule was identified in 1949. The pathophysiology of SCD is...

Sponsor: University Hospitals Cleveland Medical CenterEnrolling: 1001 location
Sickle Cell Disease
RECRUITINGPhase 2NCT02932150

Study of Tenofovir Alafenamide (TAF) in Children and Teen Participants With Chronic Hepatitis B Virus Infection

The goals of this clinical study are to compare the effectiveness, safety and tolerability of study drug, tenofovir alafenamide (TAF), versus placebo in teens and children with...

Sponsor: Gilead SciencesEnrolling: 15020 locations
Chronic Hepatitis B
RECRUITINGNCT02967068

VCRC Tissue Repository

The purpose of this study is to collect existing tissue specimens from subjects enrolled in Vasculitis Clinical Research Consortium (VCRC) studies. Analysis of these tissue...

Sponsor: University of PennsylvaniaEnrolling: 10008 locations
AortitisCutaneous VasculitisEosinophilic Granulomatosis With Polyangiitis+8
RECRUITINGNCT02986087

Feto-Endoscopic Tracheal Occlusion (FETO) for Severe Congenital Diaphragmatic Hernia

Tracheal occlusion IDE approved by FDA for congenital diaphragmatic hernia fetuses.

Sponsor: Children's Hospital Medical Center, CincinnatiEnrolling: 401 location
Congenital Diaphragmatic HerniaPulmonary HypoplasiaPulmonary; Hypertension
RECRUITINGNCT03004326

Clinical Transcriptomics in Systemic Vasculitis (CUTIS)

Multi-center observational study to evaluate the histopathology and transcriptome of cutaneous lesions in patients with several different types of vasculitis.

Sponsor: Peter MerkelEnrolling: 5010 locations
Cryoglobulinemic Vasculitis (CV)Drug-induced VasculitisEosinophilic Granulomatosis With Polyangiitis (EGPA)+7
RECRUITINGNCT03030755

Corneal Elastography and Patient Specific Modeling

The goal of this research is to develop measurement tools and simulation technology for characterizing and predicting individual responses to corneal treatments and for advancing...

Sponsor: The Cleveland ClinicEnrolling: 601 location
Cornea; EctasiaRefractive ErrorsKeratoconus
RECRUITINGNCT03047369

The Myelin Disorders Biorepository Project

The Myelin Disorders Biorepository Project (MDBP) seeks to collect and analyze clinical data and biological samples from leukodystrophy patients worldwide to support ongoing and...

Sponsor: Children's Hospital of PhiladelphiaEnrolling: 1200020 locations
LeukodystrophyWhite Matter DiseaseLeukoencephalopathies+63
RECRUITINGPhase 1 / Phase 2NCT03104491

Inotuzumab Ozogamicin Post-Transplant For Acute Lymphocytic Leukemia

This study has two phases, Phase I and Phase II. The main goal of the Phase I portion of this research study is to see what doses post-transplant inotuzumab ozogamicin can safely...

Sponsor: Leland MethenyEnrolling: 447 locations
Acute Lymphocytic Leukemia
RECRUITINGNCT03199651

Beating Lung Cancer in Ohio Protocol in Improving Survival in Patients With Stage IV Non-Small Cell Lung Cancer

This randomized clinical trial studies the Beating Lung Cancer in Ohio protocol in improving survival in patients with stage IV non-small cell lung cancer. The Beating Lung Cancer...

Sponsor: Ohio State University Comprehensive Cancer CenterEnrolling: 35841 location
Cigarette SmokerCurrent SmokerLung Adenocarcinoma+2
RECRUITINGNCT03224949

Comparison of ALD, NASH, and Healthy Control Patients

The availability of biological samples from individuals with alcoholic liver disease (ALD), as well as samples from appropriate heavy drinking, yet healthy controls and...

Sponsor: The Cleveland ClinicEnrolling: 5001 location
ALD - Alcoholic Liver Disease
RECRUITINGPhase 2NCT03383575

Azacitidine and Enasidenib in Treating Patients With IDH2-Mutant Myelodysplastic Syndrome

This phase II trial studies the side effects and how well azacitidine and enasidenib work in treating patients with IDH2-mutant myelodysplastic syndrome. Azacitidine and...

Sponsor: M.D. Anderson Cancer CenterEnrolling: 633 locations
Acute Myeloid LeukemiaBlasts 20-30 Percent of Bone Marrow Nucleated CellsChronic Myelomonocytic Leukemia+4

Showing 30 of 521 trials in Ohio. Search all trials

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Frequently Asked Questions

There are currently 521 clinical trials actively recruiting participants in Ohio. These span all phases from early-stage Phase 1 to late-stage Phase 3 trials, across 20+ conditions.

The top conditions with recruiting trials in Ohio include Ovarian Cancer, Sickle Cell Disease, Cystic Fibrosis, Colorectal Cancer, Endometrial Cancer. Each has multiple active trials across research centers in the state.

Major trial sites in Ohio include Cleveland, Columbus, Cincinnati, Canton, Akron. Most large academic medical centers and research hospitals serve as trial sites.

Review the trial listings on this page and check the eligibility criteria — we translate them into plain English. When you find a trial that fits, talk to your doctor about whether it's right for you, then contact the trial team directly using the information on the trial page.

Sources: ClinicalTrials.gov
Last updated:

Trial data sourced from the ClinicalTrials.gov API. Location data reflects registered trial sites. This site does not provide medical advice.