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TrialFinder is for informational purposes only and does not provide medical advice. Always talk to your doctor.

Clinical Trials in South Dakota

20 recruiting clinical trials across 7 cities in South Dakota (SD). Eligibility criteria explained in plain English.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
20
Total Trials
20
Recruiting Now
7
Cities
20
Conditions

Recruiting Trials in South Dakota

Clinical trial data sourced from ClinicalTrials.gov. Always consult your doctor before considering any clinical trial.

RECRUITINGNCT01793168

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international...

Sponsor: Sanford HealthEnrolling: 200002 locations
Rare DisordersUndiagnosed DisordersDisorders of Unknown Prevalence+340
RECRUITINGPhase 1 / Phase 2NCT02332668

A Study of Pembrolizumab (MK-3475) in Pediatric Participants With an Advanced Solid Tumor or Lymphoma...

Researchers are looking for new ways to treat children with different types of melanoma (skin cancer), solid tumors, and lymphomas (blood cancers) that are any of these: *...

Sponsor: Merck Sharp & Dohme LLCEnrolling: 37017 locations
MelanomaLymphomaSolid Tumor+2
RECRUITINGNCT04477928

General Population Level Estimation for Type 1 Diabetes Risk in Children During Routine Care Delivery

In partnership with Helmsley Charitable Trust, the Sanford PLEDGE Study is a large-scale, observational, feasibility study of general population screening for T1D and celiac...

Sponsor: Sanford HealthEnrolling: 330004 locations
Type 1 DiabetesCeliac Disease
RECRUITINGPhase 1NCT04970901

A Study to Evaluate the Safety and Anti-cancer Activity of Loncastuximab Tesirine in Combination With Other Anti-cancer...

The primary objective of this study is to characterize the safety and tolerability of loncastuximab tesirine in combination with polatuzumab vedotin, glofitamab, or mosunetuzumab,...

Sponsor: Adc Therapeutics S.a.Enrolling: 20020 locations
B-Cell Non-Hodgkin LymphomaRelapsed B-Cell Non-Hodgkin LymphomaRefractory B-Cell Non-Hodgkin Lymphoma
RECRUITINGNCT05142033

Avera Cancer Sequencing and Analytics Protocol (ASAP)

The purpose of this study is to characterize the breadth of molecular features present in participants receiving care within a large, integrated, community-based healthcare...

Sponsor: Avera McKennan Hospital & University Health CenterEnrolling: 250006 locations
CancerCancer DiagnosisEarly Detection of Cancer+9
RECRUITINGPhase 1NCT05848739

A Phase 1-2 of ST316 With Selected Advanced Unresectable and Metastatic Solid Tumors

This is an open-label, two-part, phase 1-2 study designed to determine the safety, tolerability, PK, pharmacodynamics (PD), and proof-of-concept efficacy of ST316 administered IV...

Sponsor: Sapience TherapeuticsEnrolling: 13011 locations
Colon CancerMetastatic Colon Cancer
RECRUITINGNCT06227572

Cognition After OSA Treatment Among Native American People (CATNAP)

This research project will develop and implement a motivational interviewing and electronic messaging intervention to address obstructive sleep apnea (OSA), positive airway...

Sponsor: Washington State UniversityEnrolling: 1401 location
Obstructive Sleep ApneaCognitive Change
RECRUITINGPhase 3NCT06227910

A Study of Vedolizumab With and Without Upadacitinib in Adults With Crohn's Disease

The main aim of this study is to learn whether vedolizumab and upadacitinib given together (also called dual targeted therapy or DTT) reduces bowel inflammation and ulcers in the...

Sponsor: TakedaEnrolling: 39620 locations
Crohn's Disease
RECRUITINGPhase 1 / Phase 2NCT06324357

Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to...

This study is open to adults aged 18 years and older with different types of HER2+ cancer that has spread and cannot be removed by surgery. People can take part in this study if...

Sponsor: Boehringer IngelheimEnrolling: 76820 locations
Metastatic Breast CancerMetastatic Gastric AdenocarcinomaGastroesophageal Junction Adenocarcinoma+2
RECRUITINGPhase 3NCT06383273

A Study to Evaluate Efficacy and Safety of MELT-300 for Procedural Sedation in Subjects Undergoing Cataract Extraction...

The goal of this clinical trial is to learn if MELT-300 works on procedural sedation in adult participants undergoing cataract extraction with lens replacement (CELR). It will...

Sponsor: Melt PharmaceuticalsEnrolling: 52812 locations
Cataract
RECRUITINGPhase 1 / Phase 2NCT06395103

Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid...

Substudy 01A is part of a platform study. The purpose of this study is to assess the efficacy and safety of zilovertamab vedotin in pediatric participants with relapsed or...

Sponsor: Merck Sharp & Dohme LLCEnrolling: 9020 locations
B-cell Acute Lymphoblastic LeukemiaDiffuse Large B-cell LymphomaBurkitt Lymphoma+2
RECRUITINGPhase 2NCT06463028

Sapanisertib and Serabelisib (PIKTOR) With Paclitaxel and a Substudy With an Insulin-Suppressing Diet in Patients With...

This is a Phase 2, multicenter, open-label, single-arm study to evaluate the efficacy and safety of sapanisertib and serabelisib (PIKTOR) with paclitaxel in participants with...

Sponsor: Faeth TherapeuticsEnrolling: 4018 locations
Endometrial Cancer
RECRUITINGPhase 3NCT06616194

A Study to Learn About the Study Medicine Called Rimegepant in Adolescents With Frequent Migraine

The purpose of this study is to learn about the effect of a study medicine called rimegepant in adolescents who have frequent migraine attacks. Rimegepant is a tablet that...

Sponsor: PfizerEnrolling: 20020 locations
Migraine
RECRUITINGPhase 2NCT06619561

A Study to Evaluate Vimseltinib in Adults With Active Chronic Graft-Versus-Host Disease (cGVHD)

The purpose of this study is to determine if vimseltinib is safe, tolerable and works effectively to treat adults with active moderate to severe cGVHD. Participants will be...

Sponsor: Deciphera Pharmaceuticals, LLCEnrolling: 4820 locations
Chronic Graft-Versus-Host Disease (cGVHD)
RECRUITINGPhase 2NCT06787612

Investigation of Ubamatamab Combination Therapy in Adult Participants With Platinum-Resistant Ovarian Cancer

This study is researching an experimental drug called ubamatamab, also referred to as "study drug". The study is focused on patients who have advanced ovarian cancer. The aim of...

Sponsor: Regeneron PharmaceuticalsEnrolling: 22020 locations
Ovarian CancerFallopian Tube CancerPrimary Peritoneal Cancer
RECRUITINGPhase 1 / Phase 2NCT06888921

A Clinical Trial to Evaluate the Safety and Efficacy of COM701 in Relapsed Platinum Sensitive Ovarian Cancer

The goal of this clinical trial is to learn if the experimental antibody COM701 delays the progression of ovarian cancer in participants with Relapsed Platinum Sensitive Ovarian...

Sponsor: Compugen LtdEnrolling: 6020 locations
Ovarian CancerOvarian Cancer Recurrent
RECRUITINGPhase 1NCT06898957

Study of Tarlatamab in Combination With YL201 With or Without Anti-programmed Death Ligand 1 (PD-L1) in Participants...

The primary objective of this study is to evaluate the safety and tolerability of tarlatamab in combination with YL201 with or without anti-PD-L1.

Sponsor: AmgenEnrolling: 20020 locations
Small Cell Lung Cancer
RECRUITINGPhase 3NCT06915025

Phase 3 Trial Evaluating the Safety & Efficacy of IMNN-001 Administered in Combination w/ Standard NACT & Adjuvant...

This is a randomized, adaptive, open label, multicenter trial to evaluate the safety and efficacy of intraperitoneal (IP) IMNN-001 plus chemotherapy compared to chemotherapy alone.

Sponsor: ImunonEnrolling: 5007 locations
Epithelial Ovarian CancerOvarian CancerFallopian Tube Cancer+1
RECRUITINGNCT07155057

Evaluating Crosslinked Hyaluronate Canalicular Gel for the Treatment of DED in Patients Undergoing Cataract Surgery

To review how patients report using a hyaluronate crosslinked canalicular gel placed before cataract surgery

Sponsor: Vance Thompson VisionEnrolling: 601 location
Dry Eye Disease (DED)
RECRUITINGPhase 4NCT07155070

Efficacy of Kera Sol Tears on Signs and Symptoms of Surgical Temporary Ocular Discomfort Syndrome (STODS) in Subjects...

Collecting data using Kera Sol tear usage during the initial two-week post-operative period after Laser-Assisted In Situ Keratomileusis (LASIK) has on the signs and symptoms of...

Sponsor: Vance Thompson VisionEnrolling: 601 location
Dry Eye

Browse Trials by State

Frequently Asked Questions

There are currently 20 clinical trials actively recruiting participants in South Dakota. These span all phases from early-stage Phase 1 to late-stage Phase 3 trials, across 20+ conditions.

The top conditions with recruiting trials in South Dakota include Ovarian Cancer, Colon Cancer, Endometrial Cancer, Fallopian Tube Cancer, Rare Disorders. Each has multiple active trials across research centers in the state.

Major trial sites in South Dakota include Sioux Falls, Aberdeen, Mitchell, Pierre, Yankton. Most large academic medical centers and research hospitals serve as trial sites.

Review the trial listings on this page and check the eligibility criteria — we translate them into plain English. When you find a trial that fits, talk to your doctor about whether it's right for you, then contact the trial team directly using the information on the trial page.

Sources: ClinicalTrials.gov
Last updated:

Trial data sourced from the ClinicalTrials.gov API. Location data reflects registered trial sites. This site does not provide medical advice.