Clinical Trials in North Carolina

North Carolina has 417 clinical trials currently recruiting participants, ranking #13 among all states. The most-studied condition is Multiple Myeloma with 14 active trials.

417

Total Trials

417

Recruiting

#13

National Rank

Conditions

Trials by Phase

178

Not Applicable

Phase 1 / Phase 2

Early Phase 1

Phase 2 / Phase 3

Phase 1

Phase 2

Phase 3

Phase 4

Top Conditions in North Carolina

#	Condition	Trials
1	Multiple Myeloma	14
2	Rheumatoid Arthritis	7
3	Cancer	7
4	Stroke	6
5	Sickle Cell Disease	6
6	Obesity	6
7	Cystic Fibrosis	6
8	Asthma	5
9	Alzheimer Disease	5
10	Generalized Myasthenia Gravis	5
11	Migraine	5
12	Ulcerative Colitis	5
13	Systemic Lupus Erythematosus	4
14	Interstitial Lung Disease	4
15	Pompe Disease	4
16	Traumatic Brain Injury	4
17	Colorectal Cancer	4
18	Myasthenia Gravis	4
19	Depression	4
20	Breast Cancer	4

Top Sponsors in North Carolina

#	Sponsor	Trials
1	Duke University	39
2	Wake Forest University Health Sciences	21
3	University of North Carolina, Chapel Hill	16
4	UNC Lineberger Comprehensive Cancer Center	9
5	Janssen Research & Development, LLC	8
6	AbbVie	8
7	Bastiaan Driehuys	6
8	Eli Lilly and Company	6
9	GlaxoSmithKline	6
10	Pfizer	5
11	AstraZeneca	5
12	Massachusetts General Hospital	4
13	Bristol-Myers Squibb	4
14	Unc Lineberger Comprehensive Cancer Center	4
15	Amgen	4

Cities With Most Trials in North Carolina

#	City	Trials
1	Durham	151
2	Chapel Hill	108
3	Winston-Salem	65
4	Charlotte	56
5	Raleigh	18
6	Wilmington	14
7	Greenville	12
8	Asheville	9
9	Morehead City	7
10	Morrisville	5
11	Huntersville	4
12	Monroe	4
13	Wake Forest	4
14	Greensboro	4
15	Cary	4

Important: This information is for research purposes only. Always talk to your doctor about whether a clinical trial is right for you.

Frequently Asked Questions

North Carolina currently has 417 clinical trials actively recruiting participants, making it #13 nationally by total trial count.

The most-studied conditions in North Carolina are Multiple Myeloma (14 trials), Rheumatoid Arthritis (7 trials), Cancer (7 trials).

Browse the conditions listed on this page to find trials recruiting in North Carolina. Each condition page shows trial details, eligibility criteria in plain English, and contact information. Always talk to your doctor about whether a trial is right for you.

Sources: ClinicalTrials.gov

Trial counts reflect currently recruiting studies listed on ClinicalTrials.gov with locations in this state.

North Carolina Trial Details →All State Statistics →

The this entity category groups every U.S. clinical trials and research registries entity sharing this attribute. The list above is the data; the paragraphs below explain what the grouping means against the broader the NIH ClinicalTrials.gov registry distribution and how to read the relative rankings within the category.

For readers using this category as a starting point, the per-entity detail pages linked from the table above carry the underlying the NIH ClinicalTrials.gov registry data in full. The category-level view is the filter; the per-entity pages are the actual answer.

Source: ClinicalTrials.gov, 2026.