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Clinical Trials in Hawaii

25 recruiting clinical trials across 4 cities in Hawaii (HI). Eligibility criteria explained in plain English.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
25
Total Trials
25
Recruiting Now
4
Cities
20
Conditions

Recruiting Trials in Hawaii

Clinical trial data sourced from ClinicalTrials.gov. Always consult your doctor before considering any clinical trial.

RECRUITINGPhase 3NCT02901184

Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure With Preserved Ejection Fraction

Heart failure with preserved ejection fraction (HFPEF) is common and deadly but without therapy. Inconclusive studies such as TOPCAT (Treatment of Preserved Cardiac Function Heart...

Sponsor: Uppsala UniversityEnrolling: 200020 locations
Heart Failure With Preserved Ejection Fraction
RECRUITINGPhase 4NCT02915198

Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes

This research will help us to learn if the medicine called metformin reduces the risk of death, heart attacks, and/or strokes in Veterans who have pre-diabetes and heart or blood...

Sponsor: VA Office of Research and DevelopmentEnrolling: 741020 locations
Prediabetic StateAtherosclerosisMetformin
RECRUITINGNCT03754114

Brain Oxygen Optimization in Severe TBI, Phase 3

BOOST3 is a randomized clinical trial to determine the comparative effectiveness of two strategies for monitoring and treating patients with traumatic brain injury (TBI) in the...

Sponsor: University of MichiganEnrolling: 109420 locations
Brain Injuries, Traumatic
RECRUITINGNCT04180930

An Evaluation of Two PTSD Assessments in an Active Duty and Military Veteran Sample

Given the high prevalence of post-traumatic stress disorder (PTSD) in veterans and active duty military, the focus of this research study is to test the reliability of two new...

Sponsor: U.S. Army Medical Research and Development CommandEnrolling: 9503 locations
Stress Disorders, Post-Traumatic
RECRUITINGNCT04278404

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of...

The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults...

Sponsor: Duke UniversityEnrolling: 500020 locations
Coronavirus Infection (COVID-19)Pulmonary Arterial HypertensionUrinary Tract Infections in Children+22
RECRUITINGNCT04739072

Minimal Residual Disease Assessment in Patients With Colorectal Cancer, the MiRDA-C Study

This study investigates if circulating tumor DNA (ctDNA) and other tumor-related molecules/chemicals released in the blood can help doctors predict if colorectal cancer may come...

Sponsor: M.d. Anderson Cancer CenterEnrolling: 100010 locations
Colorectal AdenocarcinomaStage I Colorectal Cancer AJCC v8Stage II Colorectal Cancer AJCC v8+11
RECRUITINGPhase 3NCT04829539

Comparing Brief Behavioral Therapy (BBT-CI) and Healthy Eating Education Learning (HEAL) for Cancer-Related Sleep...

This phase III trial compares BBT-CI to HEAL for the reduction of insomnia in patients with stage I-IV cancer who are receiving cancer treatment. Cancer treatment can cause side...

Sponsor: University of Rochester NCORP Research BaseEnrolling: 40020 locations
Hematopoietic and Lymphoid Cell NeoplasmMalignant Solid Neoplasm
RECRUITINGNCT05297734

Comparative Effectiveness Trial of Two Supportive Cancer Care Delivery Models for Adults With Cancer

This cluster-randomized comparative effectiveness trial compares a technology-based supportive cancer care (SCC) approach with a redesigned team-based supportive cancer care (SCC)...

Sponsor: Stanford UniversityEnrolling: 299617 locations
End of LifeCancer
RECRUITINGPhase 2NCT05422612

Department of Defense PTSD Adaptive Platform Trial - Master Protocol

This is a Phase 2 randomized, double-blinded, placebo-controlled study that will evaluate multiple potential pharmacotherapeutic interventions for PTSD utilizing an adaptive...

Sponsor: Global Coalition for Adaptive ResearchEnrolling: 80010 locations
Post Traumatic Stress Disorder
RECRUITINGPhase 3NCT05667142

A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures

This is a Phase 3, multicenter, randomized, double-blind, placebo-controlled study to evaluate the clinical efficacy, safety, and tolerability of XEN1101 administered as...

Sponsor: Xenon Pharmaceuticals Inc.Enrolling: 16020 locations
Primary Generalized Tonic-Clonic Seizures
RECRUITINGPhase 2NCT06246110

A Phase 2 Study of EIK1001 in Combo With Pembrolizumab and Chemotherapy in Patients With Stage 4 NSCLC

This study is for patients with advanced/metastatic non-small cells lung cancer (NSCLC) who have not received any treatment through the vein for the advanced disease.

Sponsor: Eikon TherapeuticsEnrolling: 7020 locations
NSCLC
RECRUITINGPhase 2NCT06321302

A Study to Test Whether BI 764524 Helps People With an Eye Condition Called Diabetic Retinopathy

This study is open to adults with diabetic retinopathy. People who have non-proliferative diabetic retinopathy of moderate or high severity can join the study. The purpose of...

Sponsor: Boehringer IngelheimEnrolling: 17820 locations
Diabetic Retinopathy
RECRUITINGNCT06321575

The Golazo® Peripheral Atherectomy System for a Safe and Effective Atherectomy (GREAT Trial)

The objective of this study is to establish reasonable assurance of safety and effectiveness of the Golazo® Peripheral Atherectomy System when used as indicated in 159 subjects...

Sponsor: Avantec VascularEnrolling: 15920 locations
Peripheral Arterial Disease
RECRUITINGPhase 3NCT06350097

Phase III, Open-label Study of First-line Osimertinib With or Without Datopotamab Deruxtecan for EGFRm Locally Advanced...

The purpose of this study is to evaluate efficacy and safety of osimertinib (tablet) in combination with Dato-DXd (i.v. infusion) compared with osimertinib (tablet) monotherapyas...

Sponsor: AstraZenecaEnrolling: 58220 locations
Non-small Cell Lung Cancer
RECRUITINGPhase 1 / Phase 2NCT06465199

Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas

The purpose of this study is to evaluate the investigational oral drug AMXT 1501 in combination with oral eflornithine (DFMO). An investigational drug is one that has not been...

Sponsor: Milton S. Hershey Medical CenterEnrolling: 2896 locations
Atypical Teratoid/Rhabdoid TumorEmbryonal Tumor With Multilayered RosettesEwing Sarcoma+3
RECRUITINGPhase 3NCT06517758

A Phase III Study to Investigate Efficacy, Safety and Tolerability of Iptacopan Compared With Placebo in Participants...

The study is a randomized, double-blind, placebo-controlled, multicenter, Phase III study, to evaluate efficacy, safety and tolerability of iptacopan in patients with AChR+ gMG...

Sponsor: Novartis PharmaceuticalsEnrolling: 14620 locations
Generalized Myasthenia Gravis
RECRUITINGNCT06855186

Symptom-Targeted Approach to Rehabilitation for Concussion (STAR-C)

Purpose: Investigators propose a three-arm RCT across two military treatment facilities:1) in-person STAR-C, 2) telehealth STAR-C, and 3) no treatment control. Outcomes will be...

Sponsor: Henry M. Jackson Foundation for the Advancement of Military MedicineEnrolling: 2222 locations
Mild Traumatic Brain Injury (mTBI)
RECRUITINGPhase 4NCT06909214

A Study to Evaluate the Clinical Outcomes of Efgartigimod PH20 SC in Adults With New-onset Generalized Myasthenia...

The main purpose of this study is to measure how well adults with new-onset gMG (which means they've had generalized disease signs and/or symptoms for less than 1 year) respond to...

Sponsor: argenxEnrolling: 3018 locations
New Onset Generalized Myasthenia Gravis (gMG)
RECRUITINGPhase 2NCT07002034

RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses

The purpose of this study is to determine if treatment with a single dose of RE104 for Injection reduces depressive symptoms or depressive symptoms mixed with anxiety symptoms in...

Sponsor: Reunion Neuroscience IncEnrolling: 10020 locations
Adjustment Disorder
RECRUITINGPhase 3NCT07018713

A Clinical Trial to Evaluate Efficacy and Safety of Xeomin® Injections for Preventing Chronic Migraine

In this clinical trial, participants with chronic migraine will receive injections with Xeomin or Placebo into muscles of the head and neck. The purpose is to measure the change...

Sponsor: Merz Therapeutics GmbHEnrolling: 78020 locations
Chronic Migraine
RECRUITINGPhase 2NCT07094516

A Clinical Trial to Learn About the Effects of VHB937 in People With Early Alzheimer's Disease

This is a multicentre, randomized, double-blind, placebo-controlled, parallel group Phase II study to evaluate the efficacy and safety of VHB937 in participants with early AD...

Sponsor: Novartis PharmaceuticalsEnrolling: 40720 locations
Alzheimer's Disease
RECRUITINGPhase 3NCT07174310

A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage...

The purpose of this study is to evaluate the efficacy, safety, and pharmacokinetics (PK) of prasinezumab compared with placebo in participants with early-stage Parkinson's disease...

Sponsor: Hoffmann-La RocheEnrolling: 90020 locations
Parkinson's Disease
RECRUITINGPhase 3NCT07207811

CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in...

This study will find out if a new medicine called NNC6019-0001 can help reduce the risk of heart-related death and illness in participants with a condition called transthyretin...

Sponsor: Novo Nordisk A/SEnrolling: 128020 locations
Transthyretin Amyloid Cardiomyopathy (ATTR CM)
RECRUITINGPhase 3NCT07321886

A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes

The purpose of this study is to evaluate the efficacy and safety of eloralintide in adults with obesity or overweight who do not have type 2 diabetes. The study has two phases: a...

Sponsor: Eli Lilly and CompanyEnrolling: 198020 locations
ObesityOverweight
RECRUITINGPhase 2NCT07431853

A Study to Learn About mRNA Vaccines Against Influenza in Adults

The purpose of this study is to learn about safety in participants taking the study vaccine (mRNA-based vaccine) and the ability of the study vaccine to trigger the body's immune...

Sponsor: PfizerEnrolling: 77015 locations
Healthy Adults

Browse Trials by State

Frequently Asked Questions

There are currently 25 clinical trials actively recruiting participants in Hawaii. These span all phases from early-stage Phase 1 to late-stage Phase 3 trials, across 20+ conditions.

The top conditions with recruiting trials in Hawaii include Heart Failure With Preserved Ejection Fraction, Prediabetic State, Atherosclerosis, Metformin, Brain Injuries, Traumatic. Each has multiple active trials across research centers in the state.

Major trial sites in Hawaii include Honolulu, ‘Aiea, Tripler AMC, Wahiawa. Most large academic medical centers and research hospitals serve as trial sites.

Review the trial listings on this page and check the eligibility criteria — we translate them into plain English. When you find a trial that fits, talk to your doctor about whether it's right for you, then contact the trial team directly using the information on the trial page.

Sources: ClinicalTrials.gov
Last updated:

Trial data sourced from the ClinicalTrials.gov API. Location data reflects registered trial sites. This site does not provide medical advice.