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Clinical Trials in Nebraska

94 recruiting clinical trials across 7 cities in Nebraska (NE). Eligibility criteria explained in plain English.

Important: This information is not medical advice. Talk to your doctor about whether a clinical trial is right for you.
94
Total Trials
94
Recruiting Now
7
Cities
20
Conditions

Recruiting Trials in Nebraska

Clinical trial data sourced from ClinicalTrials.gov. Always consult your doctor before considering any clinical trial.

RECRUITINGNCT01535430

Assessment of Eloquent Function in Brain Tumor Patients

Purpose of the study: AIM 1: Prospectively collect pre-operative \[functional magnetic resonance imaging (fMRI), diffusion tensor imaging (DTI), magnetoencephalography (MEG)\]...

Sponsor: University of NebraskaEnrolling: 751 location
Primary Brain TumorMetastatic Brain Tumor
RECRUITINGPhase 1 / Phase 2NCT02343042

Selinexor and Backbone Treatments of Multiple Myeloma Patients

This study will independently assess the efficacy and safety of 11 combination therapies in 12 arms, in dose-escalation/-evaluation and expansion phases, for the treatment of...

Sponsor: Karyopharm Therapeutics INCEnrolling: 30020 locations
Multiple Myeloma
RECRUITINGPhase 4NCT02842424

Ramipril Treatment of Claudication: Oxidative Damage and Muscle Fibrosis

Peripheral artery disease (PAD) is a manifestation of atherosclerosis that produces progressive narrowing and occlusion of the arteries supplying the lower extremities. The most...

Sponsor: University of NebraskaEnrolling: 701 location
Peripheral Arterial Disease
RECRUITINGPhase 2NCT02932150

Study of Tenofovir Alafenamide (TAF) in Children and Teen Participants With Chronic Hepatitis B Virus Infection

The goals of this clinical study are to compare the effectiveness, safety and tolerability of study drug, tenofovir alafenamide (TAF), versus placebo in teens and children with...

Sponsor: Gilead SciencesEnrolling: 15020 locations
Chronic Hepatitis B
RECRUITINGPhase 1 / Phase 2NCT03104491

Inotuzumab Ozogamicin Post-Transplant For Acute Lymphocytic Leukemia

This study has two phases, Phase I and Phase II. The main goal of the Phase I portion of this research study is to see what doses post-transplant inotuzumab ozogamicin can safely...

Sponsor: Leland MethenyEnrolling: 447 locations
Acute Lymphocytic Leukemia
RECRUITINGNCT03192267

Early Rheumatoid Arthritis Lung Disease Study

Extra-articular (outside of joints) disease occurs in approximately 50% of rheumatoid arthritis (RA) patients, with the lung being a common site of involvement. The goals of this...

Sponsor: University of NebraskaEnrolling: 1001 location
Rheumatoid Arthritis
RECRUITINGPhase 3NCT03414502

Treatment of Rheumatoid Arthritis With DMARDs: Predictors of Response

Rheumatoid arthritis (RA) is a common disease with approximately 1% prevalence. RA is also a chronic, progressive disease with no cure. Current treatment goals are to minimize...

Sponsor: University of NebraskaEnrolling: 4001 location
Rheumatoid Arthritis
RECRUITINGPhase 3NCT03592472

A Study of Pazopanib With or Without Abexinostat in Patients With Locally Advanced or Metastatic Renal Cell Carcinoma...

This is a randomized, Phase 3, double-blind, placebo-controlled study of pazopanib plus abexinostat versus pazopanib plus placebo in patients with locally advanced unresectable or...

Sponsor: Xynomic Pharmaceuticals, INC.Enrolling: 41320 locations
Renal Cell Carcinoma
RECRUITINGNCT04855396

The Biomarkers in the Hyperbaric Oxygen Brain Injury Treatment Trial (BioHOBIT)

There are no therapeutic agents that have been shown to improve outcomes from severe traumatic brain injury (TBI). Critical barriers to progress in developing treatments for...

Sponsor: University of MichiganEnrolling: 15011 locations
Traumatic Brain Injury
RECRUITINGPhase 1 / Phase 2NCT04868604

64Cu-SAR-bisPSMA and 67Cu-SAR-bisPSMA for Identification and Treatment of PSMA-expressing Metastatic Castrate Resistant...

The aim of this study is to determine the safety and efficacy of 67Cu-SAR-bisPSMA in participants with PSMA-expressing metastatic castrate resistant prostate cancer.

Sponsor: Clarity Pharmaceuticals LtdEnrolling: 547 locations
Prostatic Neoplasms, Castration-Resistant
RECRUITINGPhase 1 / Phase 2NCT04938817

Safety and Efficacy Study of Investigational Agents as Monotherapy or in Combination With Pembrolizumab (MK-3475) for...

This study is a rolling arm study of investigational agents as monotherapy or in combination with pembrolizumab in participants with anti-programmed cell death 1 (PD-1)/...

Sponsor: Merck Sharp & Dohme LLCEnrolling: 11020 locations
Small Cell Lung Carcinoma
RECRUITINGPhase 1NCT05005403

Study to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer, Head and...

Cancer is a condition where cells in a specific part of body grow and reproduce uncontrollably. Non-Small Cell Lung Cancer (NSCLC) is a solid tumor, a disease in which cancer...

Sponsor: AbbVieEnrolling: 69420 locations
Non-Small Cell Lung CancerHead and Neck Squamous Cell CarcinomaMicro Satellite Stable Colorectal Cancer+4
RECRUITINGPhase 3NCT05026749

Azithromycin Treatment for Respiratory Syncytial Virus-induced Respiratory Failure in Children

The overarching hypothesis of the ARRC trial is that administration of Azithromycin (AZM) during acute, Respiratory Syncytial Virus (RSV)-induced respiratory failure will be...

Sponsor: University of Alabama at BirminghamEnrolling: 37015 locations
Respiratory Syncytial Virus Infections
RECRUITINGNCT05135351

Study Using Prebiotics to Improve Gut Microbiome Diversity After Autologous Stem Cell Transplantation

Higher gut microbiome diversity has been associated with improved survival following autologous stem cell transplantation in multiple myeloma and lymphoma. This study hypothesises...

Sponsor: University of NebraskaEnrolling: 301 location
Multiple MyelomaLymphoma
RECRUITINGPhase 4NCT05191706

Evaluate the Safety of DEXYCU for the Treatment of Inflammation Following Ocular Surgery for Childhood Cataract

A Phase 3/4, Prospective, Randomized, Active Treatment-Controlled, Parallel-Design, Multicenter Study to Evaluate the Safety of DEXYCUfor the Treatment of Inflammation Following...

Sponsor: EyePoint Pharmaceuticals, Inc.Enrolling: 609 locations
Cataract
RECRUITINGPhase 3NCT05261139

EPIC-Peds: A Study to Learn About the Study Medicine Called PF-07321332 (Nirmatrelvir)/Ritonavir in Patients Under 18...

The purpose of this clinical trial is to learn about the safety, pharmacokinetics (pharmacokinetics helps us understand how the drug is changed and eliminated from your body after...

Sponsor: PfizerEnrolling: 16020 locations
COVID-19
RECRUITINGPhase 2NCT05268289

Study of Efficacy and Safety of LNP023 in Participants With Active Lupus Nephritis Class III-IV, +/- V

The overall purpose of this two-part study is to evaluate the efficacy, safety and tolerability of iptacopan (LNP023) in addition to standard of care treatment.

Sponsor: Novartis PharmaceuticalsEnrolling: 24020 locations
Lupus Nephritis
RECRUITINGPhase 3NCT05303064

Study to Evaluate Weight Gain as Assessed by Change in BMI Z-score in Pediatric Subjects With Schizophrenia or Bipolar...

To compare changes in body mass index (BMI) Z-score following treatment with OLZ/SAM vs olanzapine

Sponsor: Alkermes, INC.Enrolling: 22020 locations
SchizophreniaBipolar I Disorder
RECRUITINGPhase 4NCT05303636

LF111 or Drospirenone Chew vs Non-hormonal Contraceptive Methods on Bone Mineral Density in Adolescent and Adult Women

The primary objective of this study is to evaluate the impact of LF111 and drospirenone (DRSP) 3.5 mg chewable tablets on bone mineral density (BMD) at the lumbar spine after 12...

Sponsor: Insud PharmaEnrolling: 171020 locations
Change in Bone Mineral DensityBone Loss
RECRUITINGPhase 2 / Phase 3NCT05330182

LMN-201 for Prevention of C. Difficile Infection Recurrence

This is a multisite study to evaluate the safety, tolerability, and efficacy of LMN-201 in participants recently diagnosed with CDI who are scheduled to receive or are receiving...

Sponsor: Lumen Bioscience, Inc.Enrolling: 37516 locations
Clostridioides Difficile Infection
RECRUITINGNCT05349227

Comprehensive Outcomes for After Cancer Health

This study intends to explore feasibility, acceptability, and outcomes related to the use of a digital health coaching intervention for individuals who have completed primary...

Sponsor: Pack HealthEnrolling: 6257 locations
Ovarian CancerBreast CancerLung Cancer+8
RECRUITINGNCT05438732

Multicenter Clinical Study of the SING-IMT in Patients with Late-stage AMD

The objective of this study is to determine the safety and effectiveness of the smaller incision, new generation (SING), implantable miniature telescope (IMT) in patients with...

Sponsor: VisionCare, Inc.Enrolling: 12510 locations
Age-Related Macular DegenerationGeographic Atrophy
RECRUITINGPhase 1 / Phase 2NCT05636618

Targeted Alpha-Particle Therapy for Advanced Somatostatin Receptor Type 2 (SSTR2) Positive Neuroendocrine Tumors

This study is Phase I/IIa First-in-Human Study of \[212Pb\]VMT-α-NET Targeted Alpha-Particle Therapy for Advanced SSTR2 Positive Neuroendocrine Tumors

Sponsor: Perspective TherapeuticsEnrolling: 26017 locations
Neuroendocrine Tumors UnresectableNeuroendocrine Tumor MetastaticGastroenteropancreatic Neuroendocrine Tumor+3
RECRUITINGPhase 1 / Phase 2NCT05655182

A Study of BLB-201 RSV Vaccine in Infants and Children

This Phase 1/2a trial is a randomized, placebo-controlled trial to evaluate the safety, tolerability and immunogenicity of two ascending doses (10\^6 PFU and 10\^7 PFU) of...

Sponsor: Blue Lake Biotechnology Inc.Enrolling: 13711 locations
Respiratory Syncytial Virus Infections
RECRUITINGPhase 3NCT05669833

Guselkumab vs Golimumab in PsA TNF Inadequate Responder Patients

The trial is an open-label randomized study that will examine whether switching to a selective IL23 inhibitor (guselkumab) is more effective than switching to a second TNFi...

Sponsor: University of PennsylvaniaEnrolling: 6314 locations
Psoriatic Arthritis
RECRUITINGNCT05701254

Skeletal Effects of Type 1 Diabetes on Low-Trauma Fracture Risk

Patients with Type 1 Diabetes Mellitus (T1DM) have a higher risk of low-trauma (osteoporotic) fracture that is 7-12 times higher than non-diabetics. The bone density of people...

Sponsor: Creighton UniversityEnrolling: 801 location
Type 1 DiabetesOsteopeniaBone Loss+1
RECRUITINGPhase 3NCT05711394

A Study to Assess the Adverse Events and Change in Disease Activity of Oral Atogepant Tablets in Pediatric Participants...

A migraine is a moderate to severe headache on one side of the head. A migraine attack is a headache that may be accompanied by throbbing, nausea, vomiting, sensitivity to light...

Sponsor: AbbVieEnrolling: 45020 locations
Episodic Migraine
RECRUITINGNCT05864118

Comparison of Nasopharyngeal Swab v. Nasopharyngeal Saline Wash or Saliva Collection in Testing for Respiratory Viruses

Respiratory tract infections (RTIs) are prevalence community diseases and is the third leading cause of death worldwide. Rapid diagnosis of RTIs is essential as it drives decision...

Sponsor: University of NebraskaEnrolling: 10001 location
Respiratory Tract Infections
RECRUITINGPhase 1NCT05869955

A Study of CC-97540, CD-19-Targeted Nex-T CAR T Cells, in Participants With Severe, Refractory Autoimmune Diseases...

The purpose of this study is to establish the tolerability, preliminary efficacy, and pharmacokinetics of CC-97540 in participants with severe, refractory autoimmune diseases...

Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb CompanyEnrolling: 27020 locations
Systemic Lupus ErythematosusIdiopathic Inflammatory MyopathySystemic Sclerosis+1
RECRUITINGPhase 2NCT05947955

Rhu-pGSN for Acute Respiratory Distress Syndrome (ARDS)

BTI-203 is a randomized, double-blind, placebo-controlled, multicenter, Phase 2 proof-of-concept (POC) study to evaluate the efficacy and safety of rhu-pGSN plus standard of care...

Sponsor: BioAegis Therapeutics INC.Enrolling: 60020 locations
Acute Respiratory Distress SyndromeInfections

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Frequently Asked Questions

There are currently 94 clinical trials actively recruiting participants in Nebraska. These span all phases from early-stage Phase 1 to late-stage Phase 3 trials, across 20+ conditions.

The top conditions with recruiting trials in Nebraska include Peripheral Arterial Disease, Multiple Myeloma, Rheumatoid Arthritis, Respiratory Syncytial Virus Infections, Ovarian Cancer. Each has multiple active trials across research centers in the state.

Major trial sites in Nebraska include Omaha, Lincoln, Grand Island, Papillion, Bellevue. Most large academic medical centers and research hospitals serve as trial sites.

Review the trial listings on this page and check the eligibility criteria — we translate them into plain English. When you find a trial that fits, talk to your doctor about whether it's right for you, then contact the trial team directly using the information on the trial page.

Sources: ClinicalTrials.gov
Last updated:

Trial data sourced from the ClinicalTrials.gov API. Location data reflects registered trial sites. This site does not provide medical advice.